Identification of a profilin homologue in Trypanosoma brucei by complementation screening

Gene

Volumn 187, Issue 2, 1997, Pages 201-209

  Wilson, Williamina ^a   Seebeck, Thomas ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Actin; Adenylyl cyclase; CAP (cyclase associated protein); Phosphoinositide signalling; Saccharomyces cerevisiae

Indexed keywords

PROFILIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DELETION MUTANT; GENETIC COMPLEMENTATION; GENETIC SCREENING; MOLECULAR WEIGHT; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; TRYPANOSOMA BRUCEI;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CONTRACTILE PROTEINS; DNA, PROTOZOAN; GENE EXPRESSION; GENES, PROTOZOAN; GENETIC COMPLEMENTATION TEST; GENOME, PROTOZOAN; HUMANS; MICROFILAMENT PROTEINS; MOLECULAR SEQUENCE DATA; PHENOTYPE; PROFILINS; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; TEMPERATURE; TRYPANOSOMA BRUCEI BRUCEI;

INSECTA; MAMMALIA; SACCHAROMYCES CEREVISIAE; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

EID: 0030894453     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(96)00749-4     Document Type: Article

References (54)

1. Alexandre, S., Paindavoine, P., Tebabi, P., Pays, A., Halleux, S., Steinert, M. and Pays, E. (1990) Differential expression of a family of putative adenylate/guanylate cyclase genes in Trypanosoma brucei. Mol. Biochem. Parasitol. 43, 279-288.
2. Amberg, D.C., Basart, E. and Botstein, D. (1995) Defining protein interactions with yeast actin in vivo. Struct. Biol. 2, 28-35.
3. Angelopoulos, E. (1970) Pellicular microtubules in the family Trypanosomatidae. J. Protozool. 17, 39-51.
4. + gene encodes a profilin essential for cytokinesis. J. Cell Biol. 125, 1289-1301.
5. Ben Amar, M.F.A., Pays, A., Tebabi, P., Dero, B., Seebeck, T., Steinert, M. and Pays, E. (1988) Structure and transcription of the actin gene in Trypanosoma brucei. Mol. Cell. Biol. 8, 2166-2167.
6. Carruthers, V.B. and Cross, G.A.M. (1992) High efficiency clonal growth of bloodstream- and insect-form Trypanosoma brucei on agarose plates. Proc. Natl. Acad. Sci. USA 89, 8818-8821.
7. Cooley, L., Verheyen, E. and Ayers, K. (1992) chickadee encodes a profilin required for intercellular cytoplasm transport during Drosophila oogenesis. Cell 69, 173-184.
8. Cross, G.A.M. and Manning, J.C. (1973) Cultivation of Trypanosoma brucei ssp. in semi-defined and defined media. Parasitology 67, 315-331.
9. DeLange, T., Michels, P.A.M., Veerman, H.J.G., Cornelissen, A.W.C.A. and Borst, P. (1984) Many trypanosome messenger RNAs share a common 5′ terminal sequence. Nucleic Acids Res. 12, 3777-3790.
10. Edamatsu, M., Hirono, M. and Watanabe, Y. (1991) The primary structure of Tetrahymena profilin. Biochem. Biophys. Res. Commun. 170, 957-962.
11. El-Sayed, N.M.A., Alarcon, C.M., Beck, J.C., Sheffield, V.C. and Donelson, J.E. ( 1995) cDNA expressed sequence tags of Trypansoma brucei rhodesiense provide new insights into the biology of the parasite. Mol. Biochem. Parasitol. 73, 75-90.
12. Fedor-Chaiken, M., Dechenes, R. and Broach, J. (1990) SRV2, a gene required for RAS activation of adenylate cyclase in yeast. Cell 61, 329-340.
13. Fenger, U., Hofmann, Galliot, B. and Schaller, H.C. (1994) The role of the cAMP pathway in mediating the effect of head activator on nerve-cell determination and differentiation in hydra. Mechan. Devel. 47, 115-125.
14. Field, J., Vojtek, A., Ballester, R., Bolger, G., Colicelli, J., Ferguson, K., Gerst, J., Kataoka, T., Michaeli, T., Powers, S., Riggs, M., Rodgers, L., Wieland, I., Wheland, B. and Wigler, M. (1990) Cloning and characterization of CAP, the S. cerevisiae gene encoding the 70kD adenylyl cyclase associated protein. Cell 61, 319-327.
15. Freeman, N.L., Chen, Z., Horenstein, J., Weber, A. and Field, J. (1995) An actin monomer binding activity localizes to the carboxy-terminal half of the Saccharomyces cerevisiae cyclase-associated protein. J. Biol. Chem. 270, 5680-5685.
16. Freeman, N.L., Lila, T., Mintzer, K.A., Chen, Z., Pahk, A.J., Ren, R., Drubin, D.G. and Field, J. (1996) A conserved proline-rich region of the Saccharomyces cerevisiae cyclase-associated protein binds SH3 domains and modulates cytoskeletal localization. Mol. Cell. Biol. 16, 548-556.
17. Gerst, J.E., Ferguson, K., Vojtek, A., Wigler, M. and Field, J. (1991) CAP is a bifunctional component of the Saccharomyces cerevisiae adenylyl cyclase complex. Mol. Cell. Biol. 11, 1248-1257.
18. Gerst, J.E., Rodgers, L. Riggs, M. and Wigler, M. (1992) SNC1, a yeast homolog of the synaptic vesicle-associated membrane protein/ synaptobrevin gene family: genetic interactions with the RAS and CAP genes. Proc. Natl. Acad. Sci. USA 89, 4338-4342.
19. Gieselmann, R. and Mann, K. (1992) ASP-56, a new actin sequestering protein from pig platelets with homology to CAP, an adenylate cyclase-associated protein from yeast. FEBS Lett. 298, 149-153.
20. Gieselmann, R., Kwiatowski, D.J., Janmey, P.A. and Witke, W. (1995) Distinct biochemical characteristics of the two human profilin isoforms. Eur. J. Biochem. 229, 621-628.
21. 2 and inhibits its hydrolysis by phospholipase C. Science 247, 1575-1578.
22. Goldschmidt-Clermont, P.J., Kim, J.W., Machesky, L.M., Rhee, S.G. and Pollard, T.D. (1991) Regulation of phospholipase C-γ1 by profilin and tyrosine phosphorylation. Science 251, 1231-1233.
23. Gottwald, U., Brokamp, R., Karakesisoglou, I., Schleicher, M. and Noegel, A.A. (1996) Identification of a cyclase-associated protein (CAP) homologue in Dictyostelium discoideum and characterization of its interaction with actin. Mol. Biol. Cell 7, 261-272.
24. Haarer, B.K., Lillie, S.H., Adams, A.E.M., Magdolen, V., Bandlow, W. and Brown, S.S. (1990) Purification of profilin from Saccharomyces cerevisiae and analysis of profilin-deficient cells. J. Cell. Biol. 110, 105-114.
25. Haugwitz, M., Noegel, A.A., Karakesisoglou, J. and Schleicher, M. (1994) Dictyostelium amoebae that lack G-actin-sequestering profilins show defects in F-actin content, cytokinesis, and development. Cell 79, 303-314.
26. Hemphill, A., Lawson, D. and Seebeck, T. (1991) The cytoskeletal architecture of Trypanosoma brucei. J. Parasitol. 77, 603-612.
27. Honoré, B., Madsen, P., Andersen, A.H. and Leffers, H. (1993) Cloning and expression of a novel human profilin varient, profilin II. FEBS Lett. 330, 151-155.
28. Ito, H., Fukuda, Y., Murata, K. and Kimura, A. (1983) Transformation of yeast cells treated with alkali cations. J. Bacteriol. 153, 163-168.
29. Kawamukai, M., Gerst, J., Field, J., Riggs, M., Rodgers, L., Wigler, M. and Young, D. (1992) Genetic and biochemical analysis of the adenylyl cyclase associated protein, cap, in S. pombe. Mol. Cell. Biol. 3, 167-180.
30. Kwiatkowski, D.J. and Bruns, G.A.P. (1988) Human profilin. J. Biol. Chem. 263, 5910-5915.
31. Lassing, I. and Lindberg, U. (1985) Specific interaction between phosphatidylinositol 4,5-bisphosphate and the profilin: actin complex. Nature 314, 472-474.
32. Lassing, I. and Lindberg, U. (1988) Specificity of the interaction between phosphatidylinositol 4,5-bisphosphate and the profilin: actin complex. J. Cell. Biochem. 37, 255-267.
33. Mancini, P.E. and Patton, C.L. (1981) Cyclic 3′, 5′-adenosine monophosphate levels during the developmental cycle of Trypanosoma brucei brucei in the rat. Mol. Biochem. Parasitol. 3, 19-31.
34. Maniatis, T., Fritsch, E.F. and Sambrook, J. (1982) Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
35. Matviw, H., Yu, G. and Young, D. (1992) Identification of a human cDNA encoding a protein that is structurally and functionally related to the yeast adenylyl cyclase-associated CAP proteins. Mol. Cell. Biol. 12, 5033-5040.
36. Metzler, W.J., Farmer II, B.T., Constantine, K.L., Friedrichs, M.S., Lavoie, T. and Mueller, L. (1995) Refined solution structure of human profilin I. Protein Sci. 4, 450-459.
37. Mintzer, K.A. and Field, J. (1994) Interactions between adenylyl cyclase, CAP and RAS from Saccharomyces cerevisiae. Cell. Signall. 6, 681-694.
38. Ostrander, D.B., Gorman, J.A. and Carman, G.M. (1995) Regulation of profilin localization in Saccharomyces cerevisiae by phosphoinositide metabolism. J. Biol. Chem. 270, 27045-27050.
39. Paindavoine, P., Rolin, S., Van Assel, S., Geuskens, M., Jauniaux, J-C., Dinsart, C., Huet, G. and Pays, E. (1992) A gene from the variant surface glycoprotein expression site encodes one of several transmembrane adenylate cyclases located on the flagellum of Trypanosoma brucei. Mol. Cell. Biol. 12, 1218-1225.
40. Parsons, M., Nelson, R.G., Watkins, K.P. and Agabian, N. (1984) Trypanosome mRNAs share a common 5′ spliced leader sequence. Cell 38, 309-316.
41. Rose, M., Winston, F. and Hieter, P. (1990) Methods in Yeast Genetics: A Laboratory Course Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
42. Rothkegel, M., Mayboroda, O., Rhode, M., Wucherpfennig, C., Valenta, R. and Jockusch, B.M. (1996) Plant and animal profilins are functionally equivalent and stabilize microfilaments in living cells. J. Cell Sci. 109, 83-90.
43. Sanger, F., Nicklen, S. and Coulson, A.R. (1977) DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 9303-9307.
44. Sohn, R.H. and Goldschmidt-Clermont, P.J. (1994) Profilin: at the crossroads of signal transduction and the actin cytoskeleton. BioEssays 16, 465-472.
45. Staiger, C.J., Goodbody, K.C., Hussey, P.J., Valenta, R., Drøbak, B.K. and Lloyd, C.W. (1993) The profilin multigene family of maize: differential expression of three isoforms. Plant J. 4, 631-641.
46. Tanaka, M. and Shibata, H. (1985) Poly (L-proline)-binding proteins from chick embryos are a profilin and a profilactin. Eur. J. Biochem. 151, 291-297.
47. Tang, W-J. and Gilman, A.G. (1992) Adenylyl cyclases. Cell 70, 869-872.
48. Verheyen, E.M. and Cooley, L. (1994) Profilin mutations disrupt multiple actin-dependent processes during Drosophila development. Development 120, 717-728.
49. Vidali, L., Pérez, H.E., López, V.V., Noguez, R., Zamudio, F. and Sánchez, F. (1995) Purification, characterization and cDNA cloning of profilin from Phaseolus vulgaris. Plant Physiol. 108, 115-123.
50. 243 Vojtek, A.B. and Cooper, J.A. (1993) Identification and characterization of a cDNA encoding mouse CAP: a homolog of the yeast adenylyl cyclase associated protein. J. Cell Sci. 105, 777-785.
51. Vojtek, A., Haarer, B., Field, J., Gerst, J., Pollard, T.D., Brown, S. and Wigler, M. (1991) Evidence for a functional link between profilm and CAP in the yeast S. cerevisiae. Cell 66, 497-505.
52. Walter, R.D. and Opperdoes, F.R. (1982) Subcellular distribution of adenylate cyclase, cyclic-AMP phosphodiesterase, protein kinase and phosphoprotein phosphatase in Trypanosoma brucei. Mol. Biochem. Parasitol. 6, 287-295.
53. Witke, W., Sharpe, A.H. and Kwiatowski, D.J. (1993) Profilin deficient mice are not viable. Mol. Biol. Cell 4, 149a.
54. Zelicof, A. Gatica, J. and Gerst, J.E. (1993) Molecular cloning and characterization of a rat homolog of CAP, the adenylate cyclase-associated protein from Saccharomyces cerevisiae. J. Biol. Chem. 268, 13448-13453.