The effects of age on continuous learning in the radial maze

Physiology and Behavior

Volumn 61, Issue 4, 1997, Pages 609-612

  Winter, J C ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Aging; Learning; Memory; Radial maze; Rat

Indexed keywords

AGING; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; LEARNING; MALE; MEMORY; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030894163     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(96)00512-4     Document Type: Article

References (29)

1. Ammassari-Teule M., Fagoili S., Rossi-Arnaud C. Radial maze performance and open-field behaviors in aged C57BL/6 mice: Further evidence for preserved cognitive abilities during senescence. Physiol. Behav. 55:1994;341-345.
2. Barnes C. A. Aging and the physiology of spatial memory. Neurobiol. Aging. 9:1988;563-568.
3. Barnes C. A. Animal models of age-related cognitive decline. Boller F., Grafman J. Handbook of neuropsychology. 4:1990;169-196 Elsevier, Amsterdam.
4. Barnes C. A., Nadel L., Honig W. K. Spatial memory deficit in senescent rats. Can. J. Psychol. 34:1980;29-39.
5. Beatty W. W. Preservation and loss of spatial memory in aged rats and humans: implications for the analysis of memory dysfunction in dementia. Neurobil. Aging. 9:1988;557-561.
6. Beatty W. W., Bierley R. A., Boyd J. G. Preservation of accurate spatial memory in aged rats. Neurobiol. Aging. 6:1985;219-225.
7. Bierley R. A., Rixen G. J., Troster A. I., Beatty W. W. Preserved spatial memory in old rats survives 10 months without training. Behav. Neural Biol. 45:1986;223-229.
8. Gallagher M., Bostock E., King R. Effects of opiate antagonists on spatial memory in young and aged rats. Behav. Neural Biol. 44:1985;374-385.
9. Gallagher M., Burwell R., Burchinal M. Severity of spatial learning impairment inaging: Development of a learning index for performance in the Morris water maze. Behav. Neurosci. 107:1993;618-626.
10. Gallagher M., Burwell R. D., Kodsi M. H., McKinney M., Southerland S., Vella-Roundtree L., Lewis M. H. Markers for biogenic amines in the aged rat brain: Relationship to decline in spatial learning ability. Neurobiol. Aging. 11:1990;507-514.
11. Heise G. A. Behavioral methods for measuring effects of drugs on learning and memory in animals. Med. Res. Rev. 4:1984;535-558.
12. Heise G. A. Facilitation of memory and cognition by drugs. Trends Pharmacol. Sci. 8:1987;65-68.
13. Ingram D. K., Jucker M., Spangler E. L. Behavioral manifestations of aging. Mohr U., Dungworth D. L., Capen C. C. Pathobiology of the aging rat. 2:1994;149-170 International Life Sciences Institute, Washington, DC.
14. Kubanis P., Zornetzer S. F. Age-related behavioral and neurobiological changes: a review with emphasis on memory. Behav. Neural Biol. 31:1981;115-172.
15. Lee J. M., Ross E. R., Gower A., Paris J. M., Martensson R., Lorens S. A. Spatial learning deficits in the aged rat: neuroanatomical and neurochemical correlates. Brain Res. Bull. 33:1994;489-500.
16. Morris R. G. M. Spatial localization does not require the presence of local cues. Learn. Motiv. 12:1981;239-260.
17. Morris R. G. M., Garrud P., Rawlins J. N. P., O'Keefe J. Place navigation impaired in rats with hippocampal lesions. Nature. 297:1982;681-683.
18. Olton D. S. Spatial memory. Sci. Am. 236:1977;82-93.
19. Olton D. S. Characteristics of spatial memory. Hulse S. H., Fowler H., Honig W. K. Cognitive processes in animal behavior. 1978;341-373 Lawrence Earlbaum, Hillsdale, NJ.
20. Olton D. S. Age-related behavioral impairments: benefits of multiple measures of performance. Neurobiol. Aging. 14:1993;637-638.
21. Olton D. S., Samuelson R. J. Remembrance of places past: Spatial memory in rats. J. Exp. Psychol. Anim. Behav. 2:1976;97-116.
22. Peele D. B., Baron S. P. Effects of scopolamine on repeated acquisition of radial-arm maze performance by rats. J. Exp. Anal. Behav. 49:1988;275-290.
23. Peele D. B., Vincent A. Strategies for assessing learning and memory; 1978-1987: A comparison of behavioral toxicology, psychopharmacology, and neurobiology. Neurosci. Biobehav. Rev. 13:1989;33-38.
24. Rapp P. R., Amaral D. G. Individual differences in the cognitive and neurobiological consequences of normal aging. Trends Neurosci. 15:1992;340-345.
25. Sarter M. Measurement of cognitive abilities in senescent animals. J. Neurosci. 32:1987;765-774.
26. van der Staay F. J., Blokland A. Repeated assessment of spatial discrimination performance of aged rats in the Morris water escape task. Neurobiol. Learn. Mem. 65:1996;99-102.
27. Wallace J. E., Krauter E. E., Campbell B. A. Animal models of declining memory in the aged: short-term and spatial memory in the aged rat. J. Gerontol. 35:1980;355-363.
28. Willig F., Palacios A., Monmaur P., M'Harzi M., Laurent J., Delacour J. Short-termmemory, exploration, and locomotor activity in aged rats. Neurobiol. Aging. 8:1987;393-402.
29. Winocur G. A neuropsychological analysis of memory loss with age. Neurobiol. Aging. 9:1988;487-494.