Effects of dietary broccoli on human drug metabolising activity

Cancer Letters

Volumn 114, Issue 1-2, 1997, Pages 169-170

  Kall, Morten A ^a   Vang, Ole ^b   Clausen, Jørgen ^b  

^a National Food Agency of Denmark   (Denmark)

^b ROSKILDE UNIVERSITY   (Denmark)

Author keywords

Broccoli; Cyp1A2; Cyp2E1; Glutathione S transferase; Indole 3 carbinol; Metabolising enzymes

Indexed keywords

CYTOCHROME P450 ISOENZYME; ESTRONE; ESTRONE DERIVATIVE;

CONFERENCE PAPER; DIETARY INTAKE; DRUG METABOLISM; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; PRIORITY JOURNAL; VEGETABLE;

ANTICARCINOGENIC AGENTS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP2E1; DIET; GLUTATHIONE TRANSFERASE; HUMANS; HYDROXYESTRONES; INTESTINES; LIVER; LYMPHOCYTES; VEGETABLES;

BRASSICA OLERACEA VAR. BOTRYTIS;

EID: 0030894074     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(97)04652-1     Document Type: Conference Paper

References (4)

1. Kall, M.A., Vang, O. and Clausen, J. (1996) Effects of dietary broccoli on human in vivo drug metabolising enzymes: evaluation of caffeine, estrone and chlorzoxazone metabolism, Carcinogenesis, 17, 793-799.
2. Szarka, C.E., Pfeiffer, G.R., Frucht, H., Goosenberg, E.B., Litwin, S., Engstrom, P.F. and Clapper, M.L. (1994) Glutathione S-transferase activity of blood lymphocytes as a marker of human colon glutathione S-transferase activity, Cancer Res., 35, 633.
3. Nijhoff, W.A., Grubben, M.J.A.L., Nagengast, F.M., Jansen, B.M.J., Verhagen, H., Van Poppel, G. and Peters, W.H.M. (1995) Effects of consumption of Brussels sprouts on intestinal and lymphocytic glutathione S-transferases in humans, Carcinogenesis, 16, 2125-2128.
4. Bogaards, J.J., Verhagen, H., Willems, M.I., van Poppel, G. and van Bladeren, P.J. (1994) Consumption of Brussels sprouts results in elevated alpha-class glutathione S-transferase levels in human blood plasma, Carcinogenesis, 15, 1073-1075.