메뉴 건너뛰기




Volumn 75, Issue 2, 1997, Pages 127-135

Human cytokines suppress apoptosis of leukaemic CD5+ B cells and preserve expression of bcl-2

Author keywords

apoptosis; bcl 2; CD5+ B cells; CLL; cytokines

Indexed keywords

CD5 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA;

EID: 0030894009     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1038/icb.1997.17     Document Type: Article
Times cited : (53)

References (39)
  • 1
    • 0026038974 scopus 로고
    • B-cell chronic lymphocytic leukemia: Present status and future directions
    • Dighiero G, Travade P, Chevret S, Fenaux P, Chastang C, Binet JL, and the French Cooperative Group on CLL, B-cell chronic lymphocytic leukemia: Present status and future directions. Blood 1991; 78: 1901-14.
    • (1991) Blood , vol.78 , pp. 1901-1914
    • Dighiero, G.1    Travade, P.2    Chevret, S.3    Fenaux, P.4    Chastang, C.5    Binet, J.L.6
  • 2
    • 0018864596 scopus 로고
    • Discrimination of human leukemia subtypes by blow cytometric analysis of cellular DNA and RNA
    • Andreeff M, Darzynkiewicz Z, Sharpless T, Clarkson BD, Melamed MR. Discrimination of human leukemia subtypes by blow cytometric analysis of cellular DNA and RNA. Blood 1980; 55: 282-93.
    • (1980) Blood , vol.55 , pp. 282-293
    • Andreeff, M.1    Darzynkiewicz, Z.2    Sharpless, T.3    Clarkson, B.D.4    Melamed, M.R.5
  • 4
    • 0026696155 scopus 로고
    • Growth- and differentiation-associated expresion of bcl-2 in B-chronic lymphocytic leukemia cells
    • Schena M, Larsson LG, Gottardi D et al. Growth- and differentiation-associated expresion of bcl-2 in B-chronic lymphocytic leukemia cells. Blood 1992; 79: 2981-9.
    • (1992) Blood , vol.79 , pp. 2981-2989
    • Schena, M.1    Larsson, L.G.2    Gottardi, D.3
  • 6
    • 0027092054 scopus 로고
    • Responsiveness of chronic lymphocytic leukemia B cells activated via surface Igs or CD40 to B-cell tropic factors
    • Fluckiger AC, Rossi JF, Bussel A, Bryon P, Banchercau J, Defrance I. Responsiveness of chronic lymphocytic leukemia B cells activated via surface Igs or CD40 to B-cell tropic factors. Blood 1992; 80: 3173-81.
    • (1992) Blood , vol.80 , pp. 3173-3181
    • Fluckiger, A.C.1    Rossi, J.F.2    Bussel, A.3    Bryon, P.4    Banchercau, J.5    Defrance, I.6
  • 7
    • 0027440245 scopus 로고
    • Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukaemic B lymphocytes
    • Fluckiger AC, Garrone P, Durand I, Galizzi JP, Banchereau J. Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukaemic B lymphocytes. J. Exp. Med. 1993; 178: 1473-81.
    • (1993) J. Exp. Med. , vol.178 , pp. 1473-1481
    • Fluckiger, A.C.1    Garrone, P.2    Durand, I.3    Galizzi, J.P.4    Banchereau, J.5
  • 8
    • 0028043897 scopus 로고
    • IL-13 has only a subset of IL-4-like activities on B chronic lymphocytic leukemia cells
    • Fluckiger AC, Briere F, Zurawski G, Bridon JM, Banchereau J. IL-13 has only a subset of IL-4-like activities on B chronic lymphocytic leukemia cells. Immunology 1994; 83: 397-403.
    • (1994) Immunology , vol.83 , pp. 397-403
    • Fluckiger, A.C.1    Briere, F.2    Zurawski, G.3    Bridon, J.M.4    Banchereau, J.5
  • 9
    • 0027738824 scopus 로고
    • Cytokines and intracellular signals involved in the regulation of B-CLL proliferation
    • van Kooten C, Rensink I, Aarden L, van Oers R. Cytokines and intracellular signals involved in the regulation of B-CLL proliferation. Leuk. Lymphoma 1994; 12: 27-33.
    • (1994) Leuk. Lymphoma , vol.12 , pp. 27-33
    • Van Kooten, C.1    Rensink, I.2    Aarden, L.3    Van Oers, R.4
  • 10
    • 0022620860 scopus 로고
    • Chronic B-lymphocytic leukemia cells proliferate and differentiate following exposure to interferon in vitro
    • Ostlund L, Einhorn S, Robert KH, Juliusson G, Biberfeld P. Chronic B-lymphocytic leukemia cells proliferate and differentiate following exposure to interferon in vitro. Blood 1986; 67: 152-9.
    • (1986) Blood , vol.67 , pp. 152-159
    • Ostlund, L.1    Einhorn, S.2    Robert, K.H.3    Juliusson, G.4    Biberfeld, P.5
  • 11
    • 0023579983 scopus 로고
    • Spontaneous production of interleukin 1 activity by chronic lymphocytic leukaemia cells
    • Uggla C, Aguilar-Santelises M, Rosen A, Mellstedt H, Jondal M. Spontaneous production of interleukin 1 activity by chronic lymphocytic leukaemia cells. Blood 1987; 70: 1851-7.
    • (1987) Blood , vol.70 , pp. 1851-1857
    • Uggla, C.1    Aguilar-Santelises, M.2    Rosen, A.3    Mellstedt, H.4    Jondal, M.5
  • 12
    • 0024522663 scopus 로고
    • Constitutive expression of the interleukin-6 gene in chronic lymphocytic leukemia
    • Biondi A, Rossi V, Bassan R et al. Constitutive expression of the interleukin-6 gene in chronic lymphocytic leukemia. Blood 1984; 73: 1279-84.
    • (1984) Blood , vol.73 , pp. 1279-1284
    • Biondi, A.1    Rossi, V.2    Bassan, R.3
  • 13
    • 0025361921 scopus 로고
    • Production of tumor necrosis factor-α by B cell chronic lymphocytic leukemia cells: A possible regulatory role of TNF in the progression of the disease
    • Foa R, Massaia M, Cardona S et al. Production of tumor necrosis factor-α by B cell chronic lymphocytic leukemia cells: A possible regulatory role of TNF in the progression of the disease. Blood 1990; 76: 393-400.
    • (1990) Blood , vol.76 , pp. 393-400
    • Foa, R.1    Massaia, M.2    Cardona, S.3
  • 14
    • 0026600455 scopus 로고
    • Molecular investigation of the cytokines produced by normal and malignant B lymphocytes
    • Schena M, Gaidano G, Gottardi D et al. Molecular investigation of the cytokines produced by normal and malignant B lymphocytes. Leukemia 1992; 6: 120-5.
    • (1992) Leukemia , vol.6 , pp. 120-125
    • Schena, M.1    Gaidano, G.2    Gottardi, D.3
  • 15
    • 0028114406 scopus 로고
    • Serum levels of tumor necrosis factor-α in patients with B-cell chronic lymphocytic leukemia
    • Adami F, Guarini A, Pini M et al. Serum levels of tumor necrosis factor-α in patients with B-cell chronic lymphocytic leukemia. Eur. J. Cancer 1994; 30A: 1259-63.
    • (1994) Eur. J. Cancer , vol.30 A , pp. 1259-1263
    • Adami, F.1    Guarini, A.2    Pini, M.3
  • 17
    • 0027588016 scopus 로고
    • Interleukin-4 and the two isoforms of CD23 antigen: Their possible contribution to the physiopathology of chronic lymphocytic leukemia
    • Sarfati M. Interleukin-4 and the two isoforms of CD23 antigen: Their possible contribution to the physiopathology of chronic lymphocytic leukemia. Nouv. Rev. Fr. Hematol. 1993; 35: 109-13.
    • (1993) Nouv. Rev. Fr. Hematol. , vol.35 , pp. 109-113
    • Sarfati, M.1
  • 18
    • 0024556599 scopus 로고
    • Spontaneous programmed death (apoptosis) of B-chronic lymphocytic leukemia cells following their culture in vitro
    • Collins RJ, Verschuer LA, Harmon BV, Prentice RL, Pope JH, Kerr JFR. Spontaneous programmed death (apoptosis) of B-chronic lymphocytic leukemia cells following their culture in vitro. Br. J. Haem. 1989; 71: 343-50.
    • (1989) Br. J. Haem. , vol.71 , pp. 343-350
    • Collins, R.J.1    Verschuer, L.A.2    Harmon, B.V.3    Prentice, R.L.4    Pope, J.H.5    Kerr, J.F.R.6
  • 19
    • 0029940595 scopus 로고    scopus 로고
    • + B cell apoptosis. Coincidence of cell death and DNA fragmentation with reduced bcl-2 expression
    • + B cell apoptosis. Coincidence of cell death and DNA fragmentation with reduced bcl-2 expression. Br. J. Haematol. 1996; 92: 950-3.
    • (1996) Br. J. Haematol. , vol.92 , pp. 950-953
    • Tangye, S.G.1    Raison, R.L.2
  • 20
    • 0026754538 scopus 로고
    • Interleukin-4 protects chronic lymphocytic leukemia cells from death by apoptosis and upregulates bcl-2 expression
    • Dancescu M, Rubio-Trujillo M, Biron G et al. Interleukin-4 protects chronic lymphocytic leukemia cells from death by apoptosis and upregulates bcl-2 expression. J. Exp. Med. 1992; 176: 1319-26.
    • (1992) J. Exp. Med. , vol.176 , pp. 1319-1326
    • Dancescu, M.1    Rubio-Trujillo, M.2    Biron, G.3
  • 21
    • 0027379859 scopus 로고
    • Interleukin-4 inhibits apoptotic cell death and loss of the bcl-2 protein in B-chronic lymphocytic leukemia cells in vitro
    • Panayiotidis P, Ganeshaguru K, Jabbar SA, Hoffbrand AV. Interleukin-4 inhibits apoptotic cell death and loss of the bcl-2 protein in B-chronic lymphocytic leukemia cells in vitro. Br. J. Haematol. 1993; 85: 439-45.
    • (1993) Br. J. Haematol. , vol.85 , pp. 439-445
    • Panayiotidis, P.1    Ganeshaguru, K.2    Jabbar, S.A.3    Hoffbrand, A.V.4
  • 22
    • 0028174176 scopus 로고
    • Alpha-interferon (α-IFN) protects B-chronic lymphocytic leukemia cells from apoptotic cell death in vitro
    • Panayiotidis P, Ganeshaguru K, Jabbar SAB, Hoffbrand AV, Alpha-interferon (α-IFN) protects B-chronic lymphocytic leukemia cells from apoptotic cell death in vitro. Br. J. Haematol. 1994; 86: 169-73.
    • (1994) Br. J. Haematol. , vol.86 , pp. 169-173
    • Panayiotidis, P.1    Ganeshaguru, K.2    Jabbar, S.A.B.3    Hoffbrand, A.V.4
  • 23
    • 0028105132 scopus 로고
    • Interferon-alpha up-regulates bcl-2 expression and protects B-CLL cells from apoptosis in vitro and in vivo
    • Jewell AP, Worman CP, Lydyard PM, Yong KL, Giles FJ, Goldstone AH. Interferon-alpha up-regulates bcl-2 expression and protects B-CLL cells from apoptosis in vitro and in vivo. Br. J. Haematol. 1994; 88: 268-74.
    • (1994) Br. J. Haematol. , vol.88 , pp. 268-274
    • Jewell, A.P.1    Worman, C.P.2    Lydyard, P.M.3    Yong, K.L.4    Giles, F.J.5    Goldstone, A.H.6
  • 24
    • 0028171854 scopus 로고
    • Interferon-α-mediated prevention of in vitro apoptosis of chronic lymphocytic leukemia B cells: Role of bcl-2 and c-myc
    • Chaouchi N, Wallon C, Taieb J et al. Interferon-α-mediated prevention of in vitro apoptosis of chronic lymphocytic leukemia B cells: Role of bcl-2 and c-myc. Clin. Immunol. Immunother. 1994; 73: 197-204.
    • (1994) Clin. Immunol. Immunother. , vol.73 , pp. 197-204
    • Chaouchi, N.1    Wallon, C.2    Taieb, J.3
  • 25
    • 0027955125 scopus 로고
    • Interleukin 10 induces apoptotic cell death of B-chronic lymphocytic leukemia cells
    • Fluckiger AC, Durand I, Banchereau J. Interleukin 10 induces apoptotic cell death of B-chronic lymphocytic leukemia cells. J. Exp. Med. 1994; 179: 91-9.
    • (1994) J. Exp. Med. , vol.179 , pp. 91-99
    • Fluckiger, A.C.1    Durand, I.2    Banchereau, J.3
  • 26
    • 0029114152 scopus 로고
    • Growth factors can protect B-chronic lymphocytic leukemia cells against programmed cell death without stimulating proliferation
    • Jewell AP, Lydyard PM, Worman CP, Giles FJ, Goldstone AH. Growth factors can protect B-chronic lymphocytic leukemia cells against programmed cell death without stimulating proliferation. Leuk. Lymphoma 1995; 18: 159-62.
    • (1995) Leuk. Lymphoma , vol.18 , pp. 159-162
    • Jewell, A.P.1    Lydyard, P.M.2    Worman, C.P.3    Giles, F.J.4    Goldstone, A.H.5
  • 27
    • 13344282080 scopus 로고    scopus 로고
    • Interleukin-13 inhibits interleukin-2-induced proliferation and protects leukemia B cells from in vitro apoptosis
    • Chaouchi N, Wallon C, Goujard C et al. Interleukin-13 inhibits interleukin-2-induced proliferation and protects leukemia B cells from in vitro apoptosis. Blood 1996; 87: 1022-9.
    • (1996) Blood , vol.87 , pp. 1022-1029
    • Chaouchi, N.1    Wallon, C.2    Goujard, C.3
  • 28
    • 0027936671 scopus 로고
    • Interleukin-5 (IL-5) increases spontaneous apoptosis of B-cell chronic lymphocytic leukemia cells in vitro independently of bcl-2 expression, and is inhibited by IL-4
    • Mainou-Fowler T, Craig VA, Copplestone JA, Hamon MD, Prentice AG. Interleukin-5 (IL-5) increases spontaneous apoptosis of B-cell chronic lymphocytic leukemia cells in vitro independently of bcl-2 expression, and is inhibited by IL-4. Blood 1994; 84: 2297-304.
    • (1994) Blood , vol.84 , pp. 2297-2304
    • Mainou-Fowler, T.1    Craig, V.A.2    Copplestone, J.A.3    Hamon, M.D.4    Prentice, A.G.5
  • 31
    • 0028176655 scopus 로고
    • Interleukin-13, an interleukin-4-like cytokine that acts on monocytes and B-cells, but not on T cells
    • Zurawski G, de Vries JE . Interleukin-13, an interleukin-4-like cytokine that acts on monocytes and B-cells, but not on T cells. Immunol. Today. 1994; 15: 19-26.
    • (1994) Immunol. Today , vol.15 , pp. 19-26
    • Zurawski, G.1    De Vries, J.E..2
  • 32
    • 0025837444 scopus 로고
    • Antiproliferative effect of interleukin-4 in B chronic lymphocytic leukemia
    • Luo H, Rubio M, Biron G, Delespesse G, Sarfati M. Antiproliferative effect of interleukin-4 in B chronic lymphocytic leukemia. J. Immunother. 1991; 10: 418-25.
    • (1991) J. Immunother. , vol.10 , pp. 418-425
    • Luo, H.1    Rubio, M.2    Biron, G.3    Delespesse, G.4    Sarfati, M.5
  • 33
    • 0027528694 scopus 로고
    • Interleukin-6 inhibits the proliferation of B-chronic lymphocytic leukemia cells that is induced by tumor necrosis factor-α or -β
    • Aderka D, Maor Y, Novick D et al. Interleukin-6 inhibits the proliferation of B-chronic lymphocytic leukemia cells that is induced by tumor necrosis factor-α or -β. Blood 1993; 81: 2076-84.
    • (1993) Blood , vol.81 , pp. 2076-2084
    • Aderka, D.1    Maor, Y.2    Novick, D.3
  • 34
    • 0028038171 scopus 로고
    • Interleukin-4 (IL-4) inhibits proliferation and spontaneous cytokine release by chronic lymphocytic leukemia cells
    • Reittic JE, Hoffbrand AV. Interleukin-4 (IL-4) inhibits proliferation and spontaneous cytokine release by chronic lymphocytic leukemia cells. Leuk. Res. 1994; 18: 55-60.
    • (1994) Leuk. Res. , vol.18 , pp. 55-60
    • Reittic, J.E.1    Hoffbrand, A.V.2
  • 35
    • 0027483580 scopus 로고
    • α2-interferon in B-cell chronic lymphocytic leukemia: Clinical response, serum cytokine levels, and immunophenotype modulation
    • Morabito F, Callea V, Oliva B et al. α2-interferon in B-cell chronic lymphocytic leukemia: Clinical response, serum cytokine levels, and immunophenotype modulation. Leukemia 1993; 7: 366-71.
    • (1993) Leukemia , vol.7 , pp. 366-371
    • Morabito, F.1    Callea, V.2    Oliva, B.3
  • 36
    • 0025673975 scopus 로고
    • Effects of interferon-α on autocrine growth factor loops in B lymphoproliferative disorders
    • Heslop HE, Bianchi A, Cordingley FT et al. Effects of interferon-α on autocrine growth factor loops in B lymphoproliferative disorders. J. Exp. Med. 1990; 172: 1729-34.
    • (1990) J. Exp. Med. , vol.172 , pp. 1729-1734
    • Heslop, H.E.1    Bianchi, A.2    Cordingley, F.T.3
  • 37
    • 0023937119 scopus 로고
    • Tumor necrosis factor as an autocrine tumor growth factor for chronic B-cell malignancies
    • Cordingley FT, Bianchi A, Hoffbrand AV, et al. Tumor necrosis factor as an autocrine tumor growth factor for chronic B-cell malignancies. Lancet 1988; 2: 969-71.
    • (1988) Lancet , vol.2 , pp. 969-971
    • Cordingley, F.T.1    Bianchi, A.2    Hoffbrand, A.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.