Effect of cimetidine on basal and postprandial plasma concentrations of cholecystokinin and gastrin in humans

Acta Physiologica Scandinavica

Volumn 159, Issue 4, 1997, Pages 321-325

  Stoa Birketvedt G ^a,d   Waldum, H L ^b   Vonen, B ^c   Florholmen, J ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

^b Physiological Laboratory   (Norway)

^c UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

H2 receptor antagonist; Satiety

Indexed keywords

CHOLECYSTOKININ; CIMETIDINE; GASTRIN; UNCLASSIFIED DRUG;

ADULT; APPETITE; ARTICLE; BODY WEIGHT; CHOLECYSTOKININ BLOOD LEVEL; CONTROLLED STUDY; FEMALE; FOOD INTAKE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RADIOIMMUNOASSAY; STOMACH ACID SECRETION;

EID: 0030893780     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.1997.00122.x     Document Type: Article

References (25)

1. Bank, S., Barbezat, G.O., Vini, A.I., Halter, F. & Helman, C. A. 1977. Cimetidine and serum gastrin levels in man. In: W.L. Burland, M.A. Simkins (eds.) Cimetidine, pp. 155-162. Excerpta Medica, Amsterdam.
2. 2-receptor blockade with metiamide on serum gastrin levels in man. Gut 16, 186-187.
3. Burhol, P.G., Jenssen, T.G., Lygren, I., Schulz, T.B., Jorde, R. & Waldum, H.L. 1982. Iodination with iodogen and radioimmunoassay of cholecystokinin (CCK) in acidified plasma, CCK release, and molecular CCK components in man. Digestion 23, 156-168.
4. Burhol, P.G., Jenssen, T.J., Schulz, T.B., Lygren, I. & Jorde, R. 1985. Production and evaluation of rabbit cholecystokinin (CCK). Materia Med Polona 53, 34-38.
5. Carter, R.F., Bitar, K.N., Zfass, A.M. & Makhlouf, G.M. 1978. Inhibition of VIP-stimulated intestinal secretion and cyclic-AMP production by somatostatin in the rat. Gastroenterology 74, 726-730.
6. Debas, H., Farooq, O. & Grossman, M. 1975. Inhibition of gastric emptying is a physiological action of cholecystokinin. Gastroenterology 68, 1211-1217.
7. Drewe, J., Gadien, A., Rovati, L.C. & Beglinger, C. 1992. Role of circulating cholecystokinin in control of fat-induced inhibition of food intake in humans. Gastroenterology 102, 654-1659.
8. Gibbs, J., Young, R.C. & Smith, G.P. 1973. Cholecystokinin decreases food intake in rats. J Com Physiol 84, 488-495.
9. Kissileff, H.R., Pi-Sunyer, X., Thornton, J. & Smith, G.P. 1981. C-terminal octapeptide of cholecystokinin decreases intake of solid food in man. Am J Clin Nutr 34, 154-160.
10. 125I-gastrin, using Iodogen as oxidizing agent, and the use of this tracer in receptor studies. Scand J Gastroenterol 20, 569-576.
11. Konturek, J.W., Bilski, J. & Cieszkowski, M. 1992. Role of cholecystokinin in the intestinal fat- and acid-induced inhibition of gastric secretion. Reg Pept 42, 97-109.
12. Konturek, J.W., Konturek, S.J. & Domschke, W. 1995. Cholecystokinin in the control of gastric acid secretion and gastrin release in response to a meal at low and high pH in healthy subjects and duodenal ulcer patients. Scand J Gastroenterol 30, 738-744.
13. Lieverse, R.J., Jansen, J.B.M.J., Masclee, A.A.M. & Lamers, C.B.H.W. 1994. Satiety effects of cholecystokinin. Gastroenterology 106, 1451-1454.
14. Mac Gregor, I.L., Wiley, Z.D. & Martin, P.M. 1978. Effect of pentagastrin infusion on gastric emptying rate of solid food in man. Am J Dig Dis 23, 72-75.
15. Moran, T.H., Shnayder, L., Hostetler, A.M. & McHugh, P.R. 1988. Pylorectomy reduces the satiety action of cholecystokinin. Am J Physiol 255, R1059-R1063.
16. Read, N., French, C. & Cunningham, K. 1994. The role of the gut in regulating food intake in man. Nutrition Rer 52, 1-10.
17. 2-receptor antagonist on meal-stimulated acid secretion, serum gastrin and gastric emptying in patients with duodenal ulcer. Gastroenterology 71, 19-23.
18. Schmidt, W.E., Schenk, S., Nustede, R., Holst, J.J., Fölsch, U.R. & Creutzfeldt, W. 1994. Cholecystokinin is a negative regulator of gastric acid secretion and postprandial release of gastrin in humans. Gastroenterology 107, 1610-1620.
19. Smith, G., Jerome, C., Cushin, B., Eterno, R. & Simansky, K. 1981. Abdominal vagotomi blocks the satiety effect of cholecystokinin. Science 213, 1036-1037.
20. Soil, A.H., Amirian, D.A., Thomas, L.P., Reedy, T.J. & Elashoff, J.D. 1984. Gastrin receptors on isolated canine parietal cells. J Clin Invest 73, 1434-1437.
21. Sjödin, L. 1972. Influence of secretin and cholecystokinin on canine gastric secretion elicited by food and by exogenous gastrin. Acta Physiol Scand 85, 110-117.
22. Stein, L.J. & Woods, S.C. Gastrin releasing peptide reduces meal size in rats. 1982. Peptides 3, 833-836.
23. Støa-Birketvedt, G. 1993. Effect of cimetidine suspension on appetite and weight in overweight subjects. Brit Med J 306, 1091-1093.
24. Wolkowitz, O.M., Gertz, B., Weingartner, H., Beccaria, L., Thompson, K. & Liddle, R.A. 1990. Hunger in humans induced by MK-329, a specific peripheral-type cholecystokinin receptor antagonist. Biol Psychiatry 28, 169-173.
25. Zhang, DM., Bula, W. & Stellar, E. 1986. Brain cholecystokinin as a satiety peptide. Physiol Behav 36, 1183-1186.