Pancreatic reg gene expression is inhibited during cellular differentiation

Annals of Surgery

Volumn 225, Issue 3, 1997, Pages 327-332

  Zenilman, Michael E ^a   Magnuson, Thomas H ^b   Perfetti, Riccardo ^c   Chen, Jan ^a   Shuldiner, Alan R ^c  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLECYSTOKININ; COMPLEMENTARY DNA; DEXAMETHASONE; ELASTASE; GASTRIN; GENE PRODUCT; GLUCAGON; MESSENGER RNA; POLYCLONAL ANTIBODY;

ACINAR CELL; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; RAT; TISSUE REGENERATION;

ANIMALS; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; GENES, REGULATOR; PANCREAS; RATS;

EID: 0030893136     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000658-199703000-00013     Document Type: Article

References (24)

1. Terazono K, Yamamoto H, Takasawa S, et al. A novel gene activated in regenerating islets. J Biol Chem 1988; 263:2111-2114.
2. Unno M, Yonekura H, Nakagawara K, et al. Structure, chromosomal localization and expression of mouse reg genes reg I and reg II. J Biol Chem 1993; 268:15974-15982.
3. Rouquier S, Verdier JM, Iovanna J, et al. Rat pancreatic stone protein in mRNA. J Biol Chem 1991; 266:786-791.
4. Watanabe T, Yonekura H, Terazono K, et al. Complete nucleolide sequence of human reg gene and its expression in normal and tumoral tissue. J Biol Chem 1990; 265:7422-7439.
5. Zenilman ME, Magnuson TH, Swinson K, et al. Pancreatic thread protein is mitogenic to pancreatic-derived cells in culture. Gastroenterology 1996; 110:1208-1214.
6. Logsdon CD, Moessner J, Williams JA, Goldfine ID. Glucocorticoids increase amylase mRNA levels, secretory organelles and secretion in pancreatic acinar AR42J cells. J Cell Biol 1985; 100:1200-1208.
7. Guthrie J, Williams JA, Logsdon CD. Growth and differentiation of pancreatic acinar cells: independent effects of glucocorticoids on AR42J cells. Pancreas 1991; 6:506-513.
8. Logsdon CD. Glucocorticoids increase cholecystokinin receptors and amylase secretion in pancreatic acinar AR42J cells. J Biol Chem 1986; 261:2096-2101.
9. Chomczynski P. A reagent for the single step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biotechniques 1993; 15:532-537.
10. Zenilman ME, Perfetti R, Swinson K, et al. Pancreatic regeneration (reg) gene expression in a rat model of islet hyperplasia. Surgery 1996; 119:576-584.
11. Iovanna J, Orelle B, Keim V, Dagorn JC. Messenger RNA sequence and expression of rat pancreatitis associated protein, a lectin related protein overexpressed during acute experimental pancreatitis. J Biol Chem 1991; 266:24664-24669.
12. Mat-Donald RJ, Swift GH, Quinto C, et al. Primary structure of two distinct rat pancreatic preproelastases determined by sequence analysis of the complete cloned messenger ribonucleic acid sequences. Biochem 1982; 21:1453-1463.
13. Gross, J, Carlson RI, Brauer AW, et al. Isolation, characterization, and distribution of an unusual pancreatic human secretory protein. J Clin Invest 1985; 76:2115-2126.
14. Bernard JP, Adrich Z, Montalto G, et al. Immunoreactive forms of pancreatic stone protein in six mammalian species. Pancreas 1991; 6:162-167.
15. Vinik AI, Pittenger G, Rafaeloff R, Rosenberg L. Factors controlling pancreatic islet neogenesis. Tumor Biol 1993; 14:184-200.
16. Perfetti R, Egan JM, Zenilman ME, Shuldiner AR. Expression of the regenerating gene in the pancreas of aging mice. Transp Proc 1994; 26:733.
17. Zenilman ME, Chen J, Magnuson TH, Shuldiner AR. Human PTP/ reg is mitogenic to primary culture of pancreatic ductal cells. Gas- troenterology 1995: 108:A402.
18. Smith, FE, Bonner-Weir S, Leahy JL, et al. Pancreatic reg/pancre- atic stone protein (PSP) gene expression does not correlate with beta cell growth and regeneration in the rat. Diabetologia 1994; 37:994-999.
19. Logsdon CD, Alves F, Rosewicz S. Role of polyamínes in glucocorticoid effects on pancreatic acinar AR42J cell growth and differentiation. Am J Physiol 1992; 262:G285-G290.
20. Miyashita H, Yonekura H, Unno M, et al. Characterization of the 5′-regulatory region of rat Regl. Biochem Biophys Acta 1219:241-243, 1994
21. Seva C, Scemama JL, Bastie MJ, et al. Lorglumide and loxiglumide inhibit gastrin-stimulated DNA synthesis in a rat tumoral acinar pancreatic cell line (AR42J). Cancer Res 1990; 50:5829-5833.
22. Rosewicz S, Riecken EO, Kaiser A. Transient stabilization of cholecystokinin A receptor mRNA by glucocorticoids in pancreatic AR42J cells. Am J Physiol 1994; 30:G772-G777.
23. Zho W, Povoski SP, Longnecker DS, Bell RH. Novel expression of gastrin (CCK-B) receptors in azaserine-imluced rat pancreatic carcinoma: Receptor determination and characterization. Cancer Res 1992; 52:6905-6911.
24. Scemama JL, Fourmy D, Zahidi A, et al. Characterization of gastrin receptors on a rat pancreatic acinar cell line (AR42J): a possible model for studying gastrin mediated cell growth and proliferation. Gut 1987; 28:S1:233-236.