Sensitive enzyme-linked immunosorbent assay for detection of PrP(Sc) in crude tissue extracts from scrapie-affected mice

Journal of Virological Methods

Volumn 64, Issue 2, 1997, Pages 205-216

  Grathwohl, Kai Uwe D ^a   Horiuchi, Motohiro ^a   Ishiguro, Naotaka ^a   Shinagawa, Morikazu ^a  

^a OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

Author keywords

diagnosis; ELISA; scrapie; screening test

Indexed keywords

PROTEINASE K;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN SPONGIOSIS; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; ENZYME LINKED IMMUNOSORBENT ASSAY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCRAPIE; SCRAPIE AGENT; SCREENING; SPLEEN;

ANIMALS; BLOTTING, WESTERN; BRAIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; MICE; MICE, INBRED ICR; PRPSC PROTEINS; SCRAPIE; SENSITIVITY AND SPECIFICITY; SPLEEN; TISSUE EXTRACTS;

ANIMALIA; SCRAPIE PRION;

EID: 0030892871     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-0934(97)02197-6     Document Type: Article

References (34)

1. Bolton, D.C., McKinley, M.P. and Prusiner, S.B. (1982) Identification of a protein that purifies with the scrapie prion. Science 218, 1309-1311.
2. Bolton, D.C., Bendheim, P.E., Marmorstein, A.D. and Potempska, A. (1987) Isolation and structural studies of the intact scrapie agent protein. Arch. Biochem. Biophys. 258, 579-590.
3. Bolton, D.C., Rudelli, R.D., Currie, J.R. and Bendheim, P.E. (1991) Copurification of Sp33-37 and scrapie agent from hamster brain prior to detectable histopathology and clinical disease. J. Gen. Virol. 72, 2905-2913.
4. Diringer, H., Gelderblom, H., Hilmert, H., Oezel, M., Edelblut, C. and Kimberlin, R.H. (1983) Scrapie infectivity, fibrils and low molecular weight protein. Nature 306, 476-478.
5. Diringer, H. (1995) Proposed link between transmissible spongiform encephalopathies of man and animals. Lancet 346, 1208-1210.
6. Doi, S., Ito, M., Shinagawa, M., Sato, G., Isomura, H. and Goto, H. (1988) Western blot detection of scrapie-associated fibril protein in tissues outside the central nervous system from preclinical scrapie-infected mice. J. Gen. Virol. 69. 955-960.
7. Fraser, H. (1976) The pathology of natural and experimental scrapie. In: R.H. Kimberlin (Ed.), Slow Virus Diseases of Animals and Man, Ch. 12, North-Holland, Amsterdam, pp. 267-305.
8. Fraser, H. and Foster, J.D. (1993) Transmission to mice, sheep and goats and bioassay of bovine tissues. In: Proceedings of a consultation on BSE with the Scientific Veterinary Committee of the Commission of the European Community. Brussels, European Commission.
9. Sc. Arch. Virol. 141, 1863-1874.
10. C) exists in many non-neuronal tissues of sheep. J. Gen. Virol. 76, 2583-2587.
11. Ikegami, Y., Ito, M., Isomura, H., Momotani, E., Sasaki, K., Muramatsu, Y., Ishiguro, N. and Shinagawa, M. (1991) Pre-clinical and clinical diagnosis of scrapie by detection of PrP protein in tissues of sheep. Vet. Rec. 128, 271-275.
12. Jendroska, K., Heinzel, F.P., Torchia, M., Stowring, L., Kretzschmar, H.A., Kon, A., Stern, A., Prusiner, S.B. and DeArmond, S.J. (1991) Proteinase-resistant prion protein accumulation in Syrian hamster brain correlates with regional pathology and scrapie infectivity. Neurology 41, 1482-1490.
13. Kascsak, R.J., Rubenstein, R., Merz, P.A., Tonna-DeMasi, M., Fersko, R., Carp, R.I., Wisniewski, H.M. and Diringer, H. (1987) Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins. J. Virol. 61, 3688-3693.
14. Kirkwood, J.K., Wells, G.A.H., Wilesmith, J.W., Cunningham, A.A. and Jackson, S.I. (1990) Spongiform encephalopathy in an Arabian Oryx (Oryx leucoryx) and a Greater Kudu (Tragelaphus strepsiceros). Vet. Rec. 127, 418.
15. Kirkwood, J.K., Cunningham, A.A., Wells, G.A.H., Wilesmith, J.W. and Barnett, J.E.F. (1993) Spongiform encephalopathy in a herd of Greater Kudu (Tragelaphus strepsiceros): epidemiological observations. Vet. Rec. 133, 360-364.
16. Lasmézas, C.I., Cesbron, J.-Y., Deslys, J.-P., Demaimay, R., Adjou, K.T., Rioux, R., Lemaire, C., Locht, C. and Dormont, D. (1996a) Immune system-dependent and -independent replication of the scrapie agent. J. Virol. 70, 1292-1295.
17. Lasmézas, C.I., Deslys, J.-P., Demaimay, R., Adjou, K.T., Hauw, J.-J. and Dormont, D. (1996b) Strain specific and common pathogenic events in murine models of scrapie and bovine spongiform encephalopathy. J. Gen. Virol. 77, 1601-1609.
18. Meyer, R.K., McKinley, M.P., Bowman, K.A., Braunfeld, M.B., Barry, R.A. and Prusiner, S.B. (1986) Separation and properties of cellular and scrapie prion proteins. Proc. Natl. Acad. Sci. USA 83, 2310-2314.
19. Sc in sheep at the preclinical stage of scrapie and its significance for diagnosis of insidious infection. Arch. Virol. 134, 427-432.
20. Race, R., Ernst, D., Jenny, A., Taylor, W., Sutton, D. and Caughey, B. (1992a) Diagnostic implications of detection of proteinase K-resistant protein in spleen, lymph nodes and brain of sheep. Am. J. Vet. Res. 53, 883-889.
21. Race, R. and Ernst, D. (1992b) Detection of proteinase K-resistant prion protein and infectivity in mouse spleen by 2 weeks after scrapie agent inoculation. J. Gen. Virol. 73, 3319-3323.
22. Rubenstein, R., Merz, P.A., Kascsak, R.J., Scalici, C.L., Papini, M.C., Carp, R.I. and Kimberlin, R.H. (1991) Scrapie-infected spleens: analysis of infectivity, scrapie-associated fibrils, and protease-resistant proteins. J. Infect. Dis. 164, 29-35.
23. Safar, J., Ceroni, M., Piccardo, P., Gajdusek, D.C. and Gibbs, C.J. Jr. (1990) Scrapie-associated precursor proteins: antigenic relationship between species and immunocytochemical localization in normal, scrapie, and Creutzfeldt-Jakob disease brains. Neurology 40, 513-517.
24. Sakaguchi, S., Katamine, S., Yamanouchi, K., Kishikawa, M., Moriuchi, R., Yasukawa, N., Doi, T. and Miyamoto, T. (1993) Kinetics of infectivity are dissociated from PrP accumulation in salivary glands of Creutzfeldt-Jakob disease agent-inoculated mice. J. Gen. Virol. 74, 2117-2123.
25. Schreuder, B.E.C., van Keulen, L.J.M., Vromans, M.E.W., Langeveld, J.P.M. and Smits, M.A. (1996) Preclinical test for prion diseases. Nature 381, 563.
26. Serban, D., Taraboulos, A., DeArmond, S.J. and Prusiner, S.B. (1990) Rapid detection of Creutzfeldt-Jakob disease and scrapie prion proteins. Neurology 40, 110-117.
27. Shinagawa, M., Takahashi, K., Sasaki, S., Doi, S., Goto, H. and Sato, G. (1985) Characterization of scrapie agent isolated from sheep in Japan. Microbiol. Immunol. 29, 543-551.
28. van Keulen, L.J.M., Schreuder, B.E.C., Meloen, R.H., Mooij-Harkes, G., Vromans, M.E.W. and Langeveld, J.P.M. (1996) Immunohistochemical detection of prion protein in lymphoreticular tissues of sheep with natural scrapie. J. Clin. Microbiol. 34, 1228-1231.
29. Wells, G.A.H., Scott, A.C., Johnson, C.T., Gunning, R.F., Hancock, R.D., Jeffrey, M., Dawson, M., Dawson, M. and Bradley, R. (1987) A novel progressive spongiform encephalopathy in cattle. Vet. Rec. 121, 419-420.
30. Wilesmith, J.W., Ryan, J.B.M. and Atkinson, M.J. (1991) Bovine spongiform encephalopathy: epidemiological studies on the origin. Vet. Rec. 128, 199-203.
31. Will, R.G., Ironside, J.W., Zeidler, M., Cousens, S.N., Estibeiro, K., Alperovitch, A., Poser, S., Pocchiari, M., Hofman, A. and Smith, P.G. (1996) A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 347, 921-925.
32. Willoughby, K., Kelly, D.F., Lyon, D.G. and Wells, G.A.H. (1992) Spongiform encephalopathy in a captive puma (Felis concolor). Vet. Rec. 131, 431-434.
33. Wyatt, J.M., Pearson, G.R., Smerdon, T.N., Gruffydd-Jones, T.J., Wells, G.A.H. and Wilesmith, J.W. (1991) Naturally occurring scrapie-like spongiform encephalopathy in five domestic cats. Vet. Rec. 129, 233-236.
34. Zhou, H., Fisher, R.J. and Papas, T.S. (1993) Universal immuno-PCR for ultra-sensitive target protein detection. Nucleic Acid. Res. 21, 6038-6039.