Conditioned media obtained from a human mastocytosis cell strain induce mast cells expressing chymase but not tryptase from human progenitors

International Archives of Allergy and Immunology

Volumn 113, Issue 1-3, 1997, Pages 289-290

  Li, Lixin ^a   Krilis, Steven A ^a  

^a ST GEORGE HOSPITAL   (Australia)

Author keywords

C kit ligand; Chymase; Mast cellsDrug allergy; Mastocytosis; Tryptase

Indexed keywords

CHYMASE; TRYPTASE;

BONE MARROW; CELL TYPE; CONFERENCE PAPER; CONTROLLED STUDY; CULTURE MEDIUM; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; MAST CELL; MASTOCYTOSIS; PRIORITY JOURNAL; UMBILICAL CORD BLOOD;

BONE MARROW CELLS; CELLS, CULTURED; CHYMASES; CULTURE MEDIA, CONDITIONED; FETAL BLOOD; HEMATOPOIETIC STEM CELLS; HUMANS; MAST CELLS; MASTOCYTOSIS; SERINE ENDOPEPTIDASES; STEM CELL FACTOR; TRYPTASES;

EID: 0030892860     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000237576     Document Type: Article

References (5)

1. Irani AA, Schechter NM, Craig SS, DeBlois G, Schwartz LB: Two types of human mast cells that have distinct neutral protease compositions, Proc Natl Acad Sci USA 1986:83:4464-4468.
2. Wcidner N, Austen KF: Heterogeneity of mast cells at multiple body sites, Fluorescent determination of avidin binding and immunofluorcs-cent determination of chymase, tryptase, and carboxypcptidasc content, Pathol Res Pract 1993:189:156-162.
3. Li L, Zhang XT, Krilis SA: Factors that affect human mast cell and basophil growth; in Razin E, Pccht I. Rivera J (eds): Signal Transduction in Mast Cells and Basophils, Austin, Landes, in press
4. Li L, Macphcrson JJ, Adclstein S, Bunn CL, Atkinson K, Phadke K, Krilis SA: Conditioned media from a cell strain derived from a patient with mastocytosis induces preferential development of cells that possess high affinity IgE receptors and the granule protease phenotype of mature cutaneous mast cells, J Biol Chem 1995; 270:2258-2263.
5. Eklund KK, Ghildyal N, Austen KF, Stevens RL: Induction by 1L-9 and suppression by IL-3 and IL-4 of the levels of chromosome 14-de-rived transcripts that encode late-expressed mouse mast cell protcases, J Immunol 1993: 151:4266-4273