Expression of mucin-like carcinoma-associated antigen in the cyst fluid differentiates mucinous from nonmucinous pancreatic cysts

American Journal of Gastroenterology

Volumn 92, Issue 4, 1997, Pages 672-675

  Sperti, Cosimo ^a   Pasquali, Claudio ^b   Pedrazzoli, Sergio ^b   Guolo, Pietro ^b   Liessi, Guido ^b  

^a Ospedale Busonera   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; MUCIN LIKE CARCINOMA ASSOCIATED ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; CYST FLUID; CYSTADENOMA; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PANCREAS CYST; PREOPERATIVE EVALUATION; PRIORITY JOURNAL;

ANTIGENS, NEOPLASM; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; CA-15-3 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CYSTADENOMA, MUCINOUS; CYSTADENOMA, SEROUS; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; MALE; MUCINS; PANCREATIC CYST; PANCREATIC NEOPLASMS; PANCREATIC PSEUDOCYST; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL;

EID: 0030892174     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Yang EYT, Joehl RJ, Talamonti RS. Cystic neoplasms of the pancreas. J Am Coll Surg 1994;179:747-57.
2. Warshaw AL, Compton CC, Lewandrowski K, et al. Cystic tumors of the pancreas: New clinical, radiologic, and pathologic observations in 67 patients. Ann Surg 1990;212:432-45.
3. Sperti C, Cappellazzo F, Pasquali C, et al. Cystic neoplasms of the pancreas: Problems in differential diagnosis. Am Surg 1993;59:740-5.
4. De Calan L, Levard H, Hennet H, et al. Pancreatic cystadenoma and cystadenocarcinoma: Diagnostic value of preoperative morphological investigations. Eur J Surg 1995;161:35-40.
5. Sperti C, Pasquali C, Di Prima F, et al. Percutaneous CT-guided fine-needle aspiration cytology in the differential diagnosis of pancreatic lesions. Ital J Gastroenterol 1994;26:126-31.
6. Lewandrowski K, Lee J, Southern J, et al. Cyst fluid analysis in the differential diagnosis of pancreatic cysts: A new approach to the preoperative assessment of pancreatic cystic lesions. AJR 1995;164: 815-9.
7. Hammel P, Levy P, Voitot H, et al. Preoperative cyst fluid analysis is useful for the differential diagnosis of cystic lesions of the pancreas. Gastroenterology 1995;108:1230-5.
8. Lewandrowski K, Southern JF, Pins MR, et al. Cyst fluid analysis in the differential diagnosis of pancreatic cysts: A comparison of pseudocysts, serous cystadenomas, mucinous cystic neoplasms, and mucinous cystadenocarcinomas. Ann Surg 1993:217:41-7.
9. Rubin D, Warshaw AL, Southern JF, et al. Expression of CA 15-3 protein in the cyst contents distinguishes benign from malignant pancreatic mucinous cystic neoplasms. Surgery 1994;115:52-5.
10. Alles AJ, Warshaw AL, Southern JF, et al. Expression of CA 72-4 (TAG-72, in the fluid contents of pancreatic cysts: A new marker to distinguish malignant pancreatic cystic tumors from benign neoplasms and pseudocysts. Ann Surg 1994;219:131-4.
11. Sand JA, Hyoty MK, Mattila J, et al. Clinical assessment compared with cyst fluid analysis in the differential diagnosis of cystic lesions in the pancreas. Surgery 1996;119:275-80.
12. Sperti C, Pasquali C, Guolo P, et al. Evaluation of cyst fluid analysis in the diagnosis of pancreatic cysts. Ital J Gastroenterol 1995;27:479-83.
13. Sperti C, Pasquali C, Guolo P, et al. Serum tumor markers and cyst fluid analysis are useful for the diagnosis of pancreatic cystic tumors. Cancer 1996;78:237-43.
14. Laurence V, Forbes MA, Cooper EH. Use of mucin-like cancer-associated antigen (MCA) in the management of breast cancer. Br J Cancer 1991;63:1000-4.
15. Stahli C, Takacs B, Miggiano V, et al. Monoclonal antibodies against antigens on breast cancer cells. Experientia 1985;41:1377-80.
16. Stahli C, Caravatti M, Aeschbacher M, et al. Mucin-like carcinoma-associated antigen defined by three monoclonal antibodies against different epitopes. Cancer Res 1988;48:6799-802.
17. Hayes DF, Zurawski VR, Kufe DW. Comparison of circulating CA 15-3 and carcinoembryonic antigen levels in patients with breast cancer. J Clin Oncol 1986;4:1542-50.
18. Zenklusen HR, Stahli C, Gudat F, et al. The immunohistochemical reactivity of a new anti-epithelial monoclonal antibody (Mab b-12) against breast carcinoma and other normal and neoplastic human tissue. Virchows Arch A Pathol Anat Histopathol 1988:413:3-10.
19. Wagener C. Diagnostic sensitivity, diagnostic specificity and predictive value of the determination of tumor markers. J Clin Chem Clin Biochem 1984:22:969-79.
20. Centeno B, Lewandrowski K, Warshaw A, et al. Cyst fluid cytologic analysis in the differential diagnosis of pancreatic cystic tumors. Am J Clin Pathol 1994;101:483-7.
21. Ammon A, Eiffert H, Reil S, et al. Tumor-associated antigens in effusions of malignant and benign origin. Clin Investig 1993;71:437-44.
22. Yeo CJ, Bastidas JA, Lynch-Nyhan A, et al. The natural history of pancreatic pseudocysts documented by computed tomography. Surg Gynecol Obstet 1990;170:411-7.
23. Vitas GJ, Sarr MG. Selected management of pancreatic pseudocysts: Operative versus expectant management. Surgery 1992;111:123-30.
24. Freeny PC. Percutaneous management of pancreatic fluid collections. Bailliere's Clin Gastroenterol 1992:6:259-72.
25. Fernandez-del Castillo C, Warshaw AL. Cystic tumors of the pancreas. Surg Clin North Am 1995;75:1001-16.