Expression of estrogen receptor wild type and exon 5 splicing variant mRNAs in normal and endometriotic endometria during the menstrual cycle

Gynecological Endocrinology

Volumn 11, Issue 1, 1997, Pages 11-16

  Fujimoto, J ^a   Ichigo, S ^a   Hirose, R ^a   Sakaguchi, H ^a   Tamaya, T ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

Estrogen receptor exon 5 splicing variant mRNA; Estrogen receptor wild type mRNA; Normal uterine endometrium; Ovarian endometriosis menstrual cycle

Indexed keywords

ESTROGEN RECEPTOR; MESSENGER RNA; STEROID;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOMETRIOSIS; ENDOMETRIUM; EXON; FEMALE; HUMAN; MENSTRUAL CYCLE; METASTASIS POTENTIAL; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; RNA SPLICING;

EID: 0030891799     PISSN: 09513590     EISSN: None     Source Type: Journal    
DOI: 10.3109/09513599709152310     Document Type: Article

References (22)

1. Clark, J. H., Schrader, W. T. and O'Malley, B. W. (1992). Mechanism of action of steroid hormone. In Wilson, J. D. and Foster, D. W. (eds.) Williams Textbook of Endocrinology (8th edn.), pp. 35-90. (Philadelphia: W. B. Saunders)
2. Karnik, P. S., Kulkarni, S., Liu, X. P., Budd, G. T. and Bukowski, R. M. (1994). Estrogen receptor mutation in tamoxifen-resistant breast cancer. Cancer Res., 54, 349-53
3. Fujimoto, J., Hori, M., Ichigo, S., Nishigaki, M., Itoh, T. and Tamaya, T. (1994). Expression of aberrant estrogen receptor mRNA in endometrial cancers in comparison with normal endometria. Horm. Res., 42, 116-19
4. Lehrer, S., Sanchez, M., Song, H. K., Dalton, J., Levine, E., Savoretti, P., Thung, S. and Schachter, B. (1990). Oestrogen receptor B-region polymorphism and spontaneous abortion in women with breast cancer. Lancet, 335, 622-4
5. Taylor, J. A., Wilcox, A. J., Bowes, W. A., Lui, E. T. and You, M. (1993). Risk of miscarriage and a common variant of the estrogen receptor gene. Am. J. Epidemiol., 137, 1361-4
6. Schmutzler, R. K., Sanchez, M., Lehrer, S., Chaparro, C. A., Phillips, C., Rabin, J. and Schachter, B. (1994). Incidence of an estrogen receptor polymorphism in breast cancer patients. Breast Cancer Res. Treat., 19, 111-17
7. R-1 compared to the parental MCF-7 cell line. Mol. Cell Endocrinol., 109, 197-207
8. Wang, Y. and Miksicek, R. J. (1991). Identification of a dominant negative form of the human estrogen receptor. Mol. Endocrinol., 5, 1707-15
9. Miksicek, R. J., Lei, Y. and Wang, Y. (1993). Exon skipping gives rise to alternatively spliced forms of the estrogen receptor in breast tumor cells. Breast Cancer Res. Treat., 26, 163-74
10. Skipper, J. K., Young, L. J., Bergeron, J. M., Tetzlaff, M. T., Osborn, C. T. and Crews, D. (1993). Identification of an iso form of the estrogen receptor messenger RNA lacking exon four and present in the brain. Proc. Natl. Acad. Sci. USA, 90, 7172-5
11. Koehorst, S. G. A., Jacob, H. M., Thijssen, J. H. H. and Blankenstein, M. A. (1993). Wild type alternatively spliced estrogen receptor messenger RNA in human meningioma tissue and MCF-7 breast cancer cells. J. Steroid Biochem. Mol. Biol., 45, 227-33
12. Koehorst, S. G. A., Cox, J. J., Donker, G. H., Lopes da Silva, S., Burbach, J. P. H., Thijssen, J. H. H. and Blankenstein, M. A. (1994). Functional analysis of an alternatively spliced estrogen receptor lacking exon 4 isolated from MCF-7 breast cancer cells and meningioma tissue. Mol. Cell Endocrinol., 101, 237-45
13. Fuqua, S. A. W., Fitzgerald, S. D., Chamness, G. C., Tandon, A. K., McDonell, D. P., Nawaz, Z., O'Malley, B. W. and McGuire, W. L. (1991). Variant human breast tumor estrogen receptor with constitutive transcriptional activity. Cancer Res., 51, 105-9
14. Daffada, A. A. I., Johnston, S. R. D., Smith, I. E., Detre, S., King, N. and Dowsett, M. (1995). Exon 5 deletion variant estrogen receptor messenger RNA expression in relation to tamoxifen resistance and progesterone receptor/pS2 status in human breast cancer. Cancer Res., 55, 288-93
15. Fuqua, S. A. W., Fitzgerald, S. D., Allred, D. C., Elledge, R. M., Nawaz, Z., McDonell, D. P., O'Malley, B. W., Greene, G. L. and McGuire, W. L. (1992). Inhibition of estrogen receptor action by a naturally occurring variant in human breast tumors. Cancer Res., 52, 483-6
16. Gotteland, M., Desauty, G., Delarue, J. C., Liu, L. and May, E. (1995). Human estrogen receptor messenger RNA variants in both normal and tumor breast tissues. Mol. Cell Endocrinol., 112, 1-13
17. Fujimoto, J., Ichigo, S., Hirose, R., Hori, M. and Tamaya, T. (1996). Expression of estrogen receptor exon 5 splicing variant (ER E5SV) mRNA in gynecologic cancers. J. Steroid Biochem. Mol. Biol., in press
18. Noyes, R. W., Hertig, A. T. and Rock, J. (1950). Dating the endometrial biopsy. Fertil. Steril., 1, 3-5
19. Chomczynski, P. and Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-9
20. Arcari, P., Martinelli, R. and Salvatore, F. (1984). The complete sequences of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydro-genase: evidence for multiple mRNA species. Nucleic Acids Res., 12, 9179-89
21. Castles, C. G., Fuqua, S. A. W., Klotz, D. M. and Hill, S. M. (1993). Expression of a constitutively active estrogen receptor variant in the estrogen receptor-negative BT-20 human breast cancer cell line. Cancer Res., 53, 5934-9
22. Fuqua, S. A. W., Allred, D. C. and Auchus, R. J. (1993). Expression of estrogen receptor variants. J. Cell Biochem., 17G, 194-7