Synthesis of O-methylsulfonyl derivatives of D-glucose as potential alkylating agents for targeted drug delivery to the brain. Evaluation of their interaction with the human erythrocyte GLUT1 hexose transporter

Carbohydrate Research

Volumn 299, Issue 1-2, 1997, Pages 15-21

  Halmos, Thérèse ^a   Santarromana, Monique ^b   Antonakis, Kostas ^a   Scherman, Daniel ^b  

^a Lab de Chim Organique Biol   (France)

^b SANOFI   (France)

Author keywords

Blood brain barrier; Drug delivery; GKUT1 glucose transporter; Methylsulfonylglucose derivatives; Targeting; Tumor cells

Indexed keywords

ALKYLATING AGENT; GLUCOSE DERIVATIVE; GLUCOSE TRANSPORTER;

ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; DRUG PENETRATION; DRUG SYNTHESIS; ERYTHROCYTE; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, ALKYLATING; BLOOD-BRAIN BARRIER; BUSULFAN; ERYTHROCYTES; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; HUMANS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; MONOSACCHARIDE TRANSPORT PROTEINS; SULFONIC ACIDS;

EID: 0030891316     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6215(96)00328-X     Document Type: Article

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