Altered accessory cell function of alveolar macrophages: A possible mechanism for induction of Th2 secretory profile in idiopathic pulmonary fibrosis

European Respiratory Journal

Volumn 10, Issue 4, 1997, Pages 787-794

  Furuie, H ^a   Yamasaki, H ^a   Suga, M ^a   Ando, M ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Accessory cell function; Alveolar macrophages; Idiopathic pulmonary fibrosis; Interleukin 10; Type 2 T helper

Indexed keywords

INTERLEUKIN 10; MONOCLONAL ANTIBODY;

ACCESSORY CELL; ARTICLE; CELL FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HELPER CELL; HUMAN; IDIOPATHIC DISEASE; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROSIS; LUNG LAVAGE; PNEUMONIA; PRIORITY JOURNAL;

ADULT; AGED; ANTIGEN-PRESENTING CELLS; BRONCHOALVEOLAR LAVAGE FLUID; CELL CULTURE TECHNIQUES; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMANS; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-2; INTERLEUKIN-4; MACROPHAGES, ALVEOLAR; MALE; MIDDLE AGED; PULMONARY FIBROSIS; REFERENCE VALUES; SMOKING; T-LYMPHOCYTES; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0030890919     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Campbell DA, Poulter LW, Janossy G, Dubois RM. Immunohistological analysis of lung tissue from patients with cryptogenic fibrosing alveolitis suggesting local expression of immune hypersensitivity. Thorax 1985; 40: 405-411.
2. Haslam PL. Evaluation of alveolitis by studies of lung biopsies. Lung 1990; 168 (Suppl.): 984-991.
3. Cherniack RM, Banks DE, and the BAL Co-operative Group Steering Committee. Bronchoalveolar lavage constituents in healthy individuals, idiopathic pulmonary fibrosis, and selected comparison groups. Am Rev Respir Dis 1990; 141: S169-S202.
4. Haslam PL, Turton CWG, Heard B, et al. Bronchoalveolar lavage in pulmonary fibrosis: comparison of cells obtained with lung biopsy and clinical features. Thorax 1989; 44: 280-288.
5. Mosmann TR, Subash S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 1996; 17: 138-147.
6. Wallace WA, Ramage EA, Lamb D, Howie SE. A type-2 (Th2-like) pattern of immune response predominates in the pulmonary interstitium of patients with cryptogenic fibrosing alveolitis (CFA). Clin Exp Immunol 1995; 101: 436-441.
7. Doherty TM. T-cell regulation of macrophage function. Curr Opin Immunol 1995; 7: 400-404.
8. Lenschow DJ, Ho SC, Satter H, et al. Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse. J Exp Med 1995; 181: 1145-1155.
9. Kuchroo VK, Das MP, Brown JA, et al. B7-1 and B7-2 co-stimulatory molecules activate differentially the Th1/ Th2 developmental pathways: application to autoimmune disease therapy. Cell 1995; 80: 707-718.
10. 2 determine the IFN-γ level of activated human CD4+ T-cells. J Immunol 1996; 156: 1722-1727.
11. Gant V, Cluzel M, Shakoor Z, Rees PJ, Lee TH, Hamblin AS. Alveolar macrophage accessory cell function in bronchial asthma. Am Rev Respir Dis 1992; 146: 900-904.
12. Fiorentino DF, Zlotnik A, Vieira P, et al. IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J Immunol 1991; 146: 3444-3451.
13. Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T-helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 1989; 170: 2081-2095.
14. Ding L, Shevach EM. IL-10 inhibits mitogen-induced T-cell proliferation by selectively inhibiting macrophage co-stimulatory function. J Immunol 1992; 148: 3133-3139.
15. Sugimoto M, Nakashima H, Matsumoto M, Uyama E, Ando M, Araki S, Pulmonary involvement in patients with HTLV-1 associated myelopathy: increased soluble IL-2 receptors in bronchoalveolar lavage fluid. Am Rev Respir Dis 1989; 139: 1329-1335.
16. Yamasaki H, Kinoshita T, Ohmura T, et al. Lowered responsiveness of bronchoalveolar lavage T-lymphocytes in hypersensitivity pneumonitis. Am J Respir Cell Mol Biol 1991; 4: 417-425.
17. Meuer SC, Acuto O, Hussey RE, et al. Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor. Nature 1983; 303: 808-810.
18. Hogg N, MacDonald S, Slusarenko M, Beverley PC. Monoclonal antibodies specific for human monocytes, granulocytes and endothelium. Immunology 1984; 53: 753-767.
19. Selvara JP, Carpen O, Hibbs ML, Springer TA. Natural killer cell and granulocyte Fc gamma receptor III (CD16) differ in membrane anchor and signal transduction. J Immunol 1989; 143: 3283-3288.
20. Abrams JS, Roncarolo MG, Andersson U, Gleich GJ, Silver JE. Strategies of anticytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples, Immunol Rev 1992; 127: 5-24.
21. Liu MC, Proud D, Schleimer RP, Plaut M. Human lung macrophages enhance and inhibit lymphocyte proliferation. J Immunol 1984; 132: 2895-2903.
22. Laing TJ, Weiss A. Evidence for IL-2 independent proliferation in human T-cells. J Immunol 1988; 140: 1056-1062.
23. Del Prete GF, De Carli M, Romagnani S, et al. Allergen exposure induces the activation of allergen-specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders. Eur Immunol 1993; 23: 1445-1449.
24. Maggi E, Giudizi MG, Romagnani S, et al. Th2-like CD8+ T-cells showing B-cell helper function and reduced cytolytic activity in human immunodeficiency virus type-1 infection. J Exp Med 1994; 180: 489-495.
25. McMenamin C, Holt PG. The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T-cell-mediated but MHC class H-restricted CD4+ T-cell-dependent immune deviation resulting in selective suppression of immunoglobulin E production. J Exp Med 1993; 178: 889-899.
26. Prior C, Haslam PL. In vivo and in vitro production of interferon-gamma in fibrosing interstitial lung diseases. Clin Exp Immunol 1992; 88: 280-287.
27. Duncan MR, Berman B. Gamma-interferon is the lymphokine and β-interferon is the monokine responsible for the inhibition of fibroblast collagen production and late but not early fibroblast proliferation. J Exp Med 1985; 112: 516-527.
28. Pfeffer LM, Murphy JS, Tamm I. Interferon effects on the growth and division of human fibroblasts. Exp Cell Res 1979; 121: 111-120.
29. Sempowski GD, Beckmann MP, Derdak S, Phipps RP. Subsets of murine lung fibroblasts express membranebound and soluble IL-4 receptors. J Immunol 1994; 152: 3606-3614.
30. Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T-cell clones. 1. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136: 2348-2357.
31. Campbell DA, Poulter LW, Janossy G, du Bois RM. Immunological analysis of lung tissue from patients with cryptogenic fibrosing alveolitis suggests local expression of immune hypersensitivity. Thorax 1985; 40: 405-411.
32. Hoogsteden HC, van Hal PTW, Wijkhuijs JM, Hop W, Hilvering C. Differences in expression of monocyte/ macrophage surface antigens in peripheral blood and bronchoalveolar lavage cells in interstitial lung disease. Lung 1993; 171: 149-160.