Gene expression in kidney using transgenic approaches

Experimental Nephrology

Volumn 5, Issue 2, 1997, Pages 157-167

  Kopp, Jeffrey B ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

focal segmental glomerulosclerosis; HIV associated nephropathy; kidney disease; transgenic animals

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; FOCAL GLOMERULOSCLEROSIS; GENETIC MANIPULATION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; KIDNEY DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW; TRANSGENIC ANIMAL;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANIMALS; CROSSES, GENETIC; GENE EXPRESSION; GENE THERAPY; GENES, VIRAL; GENETIC ENGINEERING; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HIV-1; HUMANS; KIDNEY DISEASES; MICE; MICE, TRANSGENIC; PHENOTYPE; REGULATORY SEQUENCES, NUCLEIC ACID;

EID: 0030890728     PISSN: 10187782     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (50)

1. Jaenisch R, Mintz B: Simian virus 40 DNA sequences in DNA of healthy adult mice derived from preimplantation blastocysts injected with viral DNA. Proc Natl Acad Sci USA 1974;71:1250-1254.
2. Striker LJ, Doi T, Striker GE: Transgenic mice in renal research. Adv Nephrol 1991;20:91-108.
3. Grandaliano G, Choudhury GG, Abboud HE: Transgenic animal models as a tool in the diagnosis of kidney diseases. Semin Nephrol 1995; 15:43-49.
4. Kopp JB, Klotman PE: Transgenic animal models of renal development and pathogenesis. Am J Physiol 1995;38:F601-F620.
5. Palmiter RD, Behringer RR, Quaife CJ, Maxwell R, Maxwell IH, Brinster RL: Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene. Cell 1987;50:435-443.
6. Hyink DP, St John PL, Abrahamson DR: Endogenous, not exogenous, origin of glomerular vasculature in fetal kidney grafts. J Am Soc Nephrol 1995;6:697.
7. Diamond LE, Oldham ER, Platt JL, Waldmann H, Tone M, Walsh LA, Logan JS: Cell-and tissue-specific expression of a human CD59 minigenc in transgenic mice. Transplant Proc 1994;26:1239.
8. Kagan D, Platt J, Logan J, Byrne GW: Expression of complement regulatory factors using heterologous promoters in transgenic mice. Transplant Proc 1994;26:1242.
9. IJzermans JNM, Schraa EO, Bonthuis F, Yannoutsos N, Marquet RL: In vivo evaluation of human membrane cofactor protein in transgenic mice. Transplant Proc 1996;28:671-672.
10. Palmiter RD, Sandgren EP, Koeller DM, Brinster RL: Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice. Mol Cell Biol 1993;13:5266-5275.
11. Palmiter RD, Norstedt G, Gelinas RE, Hammer RE, Brinster RL: Metallothionein-human GH fusion genes stimulate growth of mice. Science 1983;222:809-814.
12. Stewart TA, Hollingshead PG, Pitts SL: Multiple regulatory domains in the mouse mammary tumor virus long terminal repeat revealed by analysis effusion genes in transgenic mice. Mol Cell Biol 1988;8:473-479.
13. Wyborski DL, Short JM: Analysis of inducers of the E. coli lac repressor system in mammalian cells and whole animals. Nucleic Acids Res 1991;19:4647-4653.
14. Gossen M, Bujard H: Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 1992;89:5547-5551.
15. Furth PA, St. Onge L, Böger H, Gruss P, Gossen M, Kistner A, Bujard H, Henninghausen L: Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter. Proc Natl Acad Sci USA 1994;91:9302-9306.
16. Passman RS, Fishman GI: Regulated expression of foreign genes in vivo after germline transfer. J Clin Invest 1994;94:2421-2425.
17. Gossen M, Freundlib S, Bender G, Muller T, Hillen W, Bujard H: Transcriptional activation by tetracyclines in mammalian cells. Science 1995;268:1766-1769.
18. Hogan B, Beddington R, Costantini F, Lacy E: Manipulating the Mouse Embryo: A Laboratory Manual, ed 2. Cold Spring Harbor, Cold Spring Harbor Laboratory Press, 1994.
19. Wassarman PM, DePamphilis ML (eds): Guide to Techniques in Mouse Development. Methods in Enzymology. San Diego, Academic Press, 1993, vol 225.
20. Palmiter RD, Brinster RL: Germ-line transformation of mice. Annu Rev Genet 1986;20: 465-499.
21. Monastersky GM, Robl JM (eds): Strategies in Transgenic Animal Science. Washington, American Society of Microbiology, 1995.
22. Mann JR, McMahon AP: Factors influencing frequency production of transgenic mice. Methods Enzymol 1993;25:771-781.
23. Rappaport J, Kopp JB, Klotman PE: Host-virus interactions and the molecular regulation of HIV-1: Role in the pathogenesis of HIV-associated nephropathy. Kidney Int 1994;46: 16-27.
24. Kopp JB, Klotman PE: Animal models of lentivirus-associated renal disease; in Berns J, Kimmel P (eds): Renal and Urologie Aspects of HIV Infection. New York, Churchill Livingstone, 1995, pp 389-404.
25. Klotman PE, Rappaport J, Ray P, Kopp JB, Franks R, Bruggeman LA, Notkins AL: Transgenic models of HIV-1. AIDS 1995;9:313-324.
26. Leonard JM, Abramczuk JW, Pezen DS, Rutledge R, Belcher JH, Hakim F, Shearer G, Lamperth L, Travis W, Frederickson T, Notkins AL, Martin MA: Development of disease and virus recovery in transgenic mice containing HIV proviral DNA. Science 1988;242: 1665-1670.
27. Dickie P, Felser J, Eckhaus M, Bryant J, Silver J, Marines N, Notkins AL: HIV-associated nephropathy in transgenic mice expressing HIV-1 genes. Virology 1991;185:109-119.
28. Kopp JB, Klotman ME, Adler SH, Bruggeman LA, Dickie P, Marinos NJ, Eckhaus M, Bryant JL, Notkins AL, Klotman PE: Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type 1 genes. Proc Natl Acad Sci USA 1992;89:1577-1581.
29. MacKay K, Striker LJ, Pinkert CA, Brinster RL, Striker GE: Glomerulosclerosis and renal cysts in mice transgenic for the early region of SV40. Kidney Int 1987;32:827-837.
30. Godley LA, Kopp JB, Eckhaus M, Paglino JJ, Owens J, Varmus HE: Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys. Genes Dev 1996;10:836-850.
31. Kajiyama W, Klotman PE, Dickie P, Kopp JB: HIV-1 genes are expressed in glomerular and tubular epithelial cells in HIV-transgenic mouse kidney. AIDS Res Hum Retrovir 1995; 11(suppl 1):153.
32. Kimmel PL, Philips TM, Tinkle BT, Jay G: HIV accessory proteins and transforming growth factor-β1 are associated with nephropathy in a transgenic mouse model (abstract). J Invest Med 1996;44:321.
33. Mehtali M, Kieny MP: HIV-1 Tat and Revrelated pathologies in transgenic mice. AIDS Res Hum Retroviruses 1992;8:901.
34. Prakhash O, Harlan R, Chen I-L, Randeri H, Zhining D, Ren T, Coleman R: Transactivation of the HIV-1 LTR by tat in transgenic mice is influenced by the chromosomal site of the LTR integration. AIDS Res Hum Retroviruses 1994;10(suppl 3):139.
35. Lafond RE, Giammalvo JT, Norkin LC: Relationship between expression of epidermal growth factor and simian virus 40 T antigen in a line of transgenic mice. Transgenic Res 1995; 4:306-314.
36. Dalrymple SA, Beemon KL: BK virus T antigens induce kidney carcinomas and thymoproliferative disorders in transgenic mice. J Virol 1990;64:1182-1191.
37. Baskar JF, Smith PP, Nilaver G, Jupp RA, Hoffman S, Peffer NJ, Tenney DJ, Colberg-Poley AM, Ghazal P, Nelson JA: The enhancer domain of the human cytomegalovirus major immediate-early promoter determines cell type-specific expression in transgenic mice. J Virol 1996;70:3207-3214.
38. Choi Y, Henrard D, Lee I, Ross SR: The mouse mammary tumor virus long terminal repeat directs expression in epithelial and lymphoid cells in different tissues in transgenic mice. J Virol 1987;61:3013-3019.
39. Harats D, Kurihara H, Belloni P, Oakley H, Ziober A, Ackley D, Cain G, Kurihara Y, Lawn R, Sigal E: Targeting gene expression to the vascular wall in transgenic mice using the murine preproendothelin-1 promoter. J Clin Invest 1995;95:1335-1344.
40. Sigmund CD, Jones CA, Fabian JR, Mullins JJ, Gross KW: Tissue and cell specific expression of a renin promoter-reporter gene construct in transgenic mice. Biochem Biophys Res Commun 1990;170:344-350.
41. Vicart P, Schwartz B, Vandewalle A, Bens M, Delouis C, Panthier J-J, Pournin S, Babinet C, Paulin D: Immortalization of multiple cell types in transgenic mice using a transgene containing the vimentin promoter and a conditional oncogene. Exp Cell Res 1994;214:35-45.
42. Schaffner DL, Barrios R, Massey C, Banez EI, Ou CN, Rajagopalan S, Aguilar-Cordova E, Lebovitz RM, Overbeek PA, Lieberman MW: Targeting of the ras T24 oncogene to the proximal convoluted tubules in transgenic mice results in hyperplasia and polycystic kidneys. Am J Pathol 1993;142:1051-1060.
43. Lo D, Burkly LC, Widera G, Cowing C, Flavell RA, Palmiter RD, Brinster RL: Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells. Cell 1988;53:159-168.
44. Short MK, Clouthier DE, Schaefer IM, Hammer RE, Magnuson MA, Beale EG: Tissue-specific, developmental, hormonal, and dietary regulation of rat phosphoenolpyruvate carboxykinase-human growth hormone fusion genes in transgenic mice. Mol Cell Biol 1992; 12:1007-1020.
45. Thorey IS, Ceceña G, Reynolds W, Oshima RG: Alu sequence involvement in transcriptional insulation of the keratin 18 gene in transgenic gene in mice. Mol Cell Biol 1993;13: 6742-6751.
46. Blau S, Daly L, Fienberg A, Teitelman G, Ehrlich ME: DARPP-32 promoter directs transgene expression to renal thick ascending limb of loop of Henle. Am J Physiol 1995;38:F564-F570.
47. Maxwell PH, Osmond MK, Pugh CW, Heryet A, Nicholls LG, Tan CC, Doe BG, Ferguson DJ, Johnson MH, Ratcliffe PJ: Identification of the renal erythropoietin-producing cells using transgenic mice. Kidney Int 1993;44:1149-1162.
48. Hanaoka K, Hayasak M, Uetuski T, Fujisawa-Sehara A, Nabeshima Y-I: A stable cellular marker for the analysis of mouse chimeras: The bacterial chloramphenicol acctyltransferase gene driven by the human elongation factor 1α promoter. Differentiation 1991;48:183-189.
49. Gunning P, Leavitt J, Muscat G, Ng S-Y, Kedes L: A human beta-actin expression vector directs high level accumulation of antisense transcripts. Proc Natl Acad Sci USA 1987;46: 4831-4835.
50. Halmekytö M, Hyttinen J-M, Sinervirta R, Utrianinen M, Myöhänen S, Voipio H-M, Wahlfors J, Syrjänen K, Alhonen L, Jänne J: Transgenic mice aberrantly expressing human ornithine decarboxylase gene. J Biol Chem 1991;266:19746-19751.