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Volumn 38, Issue 17, 1997, Pages 3093-3096

Synthesis of (S)- and (R)-tert leucine enabling direct coupling with α-amino acid esters via β-lactam-derived α-amino acid N-carboxy anhydrides

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SYNTHESIS; ARTICLE; CHIRALITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030890690     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00553-4     Document Type: Article
Times cited : (16)

References (15)
  • 8
    • 0028789812 scopus 로고
    • For a solution to this problem by using racemic α-(2,6-dichlorophenyl)ethyl amine, see: c) Hashimoto, Y; Kai, A.; Saigo, K. Tetrahedron Lett 1995, 36, 8821.
    • (1995) Tetrahedron Lett , vol.36 , pp. 8821
    • Hashimoto, Y.1    Kai, A.2    Saigo, K.3
  • 11
    • 84920294901 scopus 로고    scopus 로고
    • note
    • 3H).
  • 12
    • 84920294900 scopus 로고    scopus 로고
    • note
    • 4 position in 2b shows as a doublet at 3.41 ppm, while the corresponding one in 3b appears at 3.58 ppm.
  • 13
    • 84920294899 scopus 로고    scopus 로고
    • note
    • Preparative HPLC was performed on a Lichrosorβ-Si60 7μM column with flow rates of 10 ml/min. (EtOAc/Hex., 40:60) and using a UV detector (254 nm). Retention times: 4, 32.55 min. and 5, 38.74 min.
  • 14
    • 84920294898 scopus 로고    scopus 로고
    • note
    • The X-ray data have been deposited at Cambridged Crystallographic Data Center.
  • 15
    • 84920294897 scopus 로고    scopus 로고
    • note
    • 25= +0.7 (c=0.7, MeOH).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.