Endothelin-1 potently stimulates chloride secretion and inhibits Na+-glucose absorption in human intestine in vitro

Journal of Physiology

Volumn 499, Issue 2, 1997, Pages 391-402

  Kuhn, Michaela ^a   Fuchs, Martin ^a   Beck, Franz X ^b   Martin, Silke ^a   Jähne, Joachim ^c   Klempnauer, Jürgen ^c   Kaever, Volkhard ^c   Rechkemmer, Gerhard ^d   Forssmann, Wolf Georg ^a  

^a IPF PHARMACEUTICALS GMBH   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BUMETANIDE; CHLORIDE ION; ENDOTHELIN 1; GLUCOSE; PHLORIZIN; SODIUM ION;

ARTICLE; CHLORIDE TRANSPORT; CLINICAL ARTICLE; COLON MUCOSA; CONTROLLED STUDY; ELECTRON PROBE MICROANALYSIS; EPITHELIUM CELL; GLUCOSE ABSORPTION; GLUCOSE TRANSPORT; HUMAN; HUMAN TISSUE; INTESTINE ABSORPTION; INTESTINE INNERVATION; INTESTINE VILLUS; JEJUNUM MUCOSA; PRIORITY JOURNAL; SODIUM CELL LEVEL; SODIUM TRANSPORT;

EID: 0030889806     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.1997.sp021936     Document Type: Article

References (25)

1. BECK, F. X., SCHMOLKE, M., GUDER, W. G., DÖRGE, A. & THURAU, K. (1992). Osmolytes in renal medulla during rapid changes in papillary tonicity. American Journal of Physiology 262, F849-856.
2. BROWN, M. A. & SMITH, P. L. (1991). Endothelin: a potent stimulator of intestinal ion secretion in vitro. Regulatory Peptides 36, 1-19.
3. EHRENREICH, H., ANDERSON, R. W. & FOX, C. H. (1990). Endothelins, peptides with potent vasoactive properties, are produced by human macrophages. Journal of Experimental Medicine 17, 1741-1748.
4. FURUYA, K., FURUYA, S. & YAMAGISHI, S. (1994). Intracellular calcium responses and shape conversions induced by endothelin in cultured subepithelial fibroblasts of rat duodenal villi. Pflügers Archiv 428, 97-104.
5. +/glucose cotransporter expression by protein kinases in Xenopus laevis oocytes. Journal of Biological Chemistry 271, 14740-14746.
6. INAGAKI, H., BISHOP, A. E., ESCRIG, C., WHARTON, J., ALLENMERSH, T. G. & POLAK, J. M. (1991). Localization of endothelin like immunoreactivity and endothelin binding sites in human colon. Gastroenterohgy 101, 47-54.
7. INOUE, A., YANAGISAWA, M., KIMRA, S., KASUYA, Y., MIYAUCHI, T., GOTO, K. & MASAKI, T. (1989). The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by separate genes. Proceedings of the National Academy of Sciences of the USA 86, 2863-2867.
8. ISHIDA, N., TSUJIOKA, K., TOMOI, M., SAIDA, K. & MITSUI, Y. (1989). Differential activities of two distinct endothelin family peptides on ileum and coronary artery. FEBS Letters 247, 337-340.
9. KIMMICH, G. A. (1981). Intestinal absorption of sugar. In Physiology of the Gastrointestinal Tract, ed. JOHNSON, L. R., pp. 1035-1061. Raven Press, New York.
10. KIYOHARA, T., OKUNO, M., NAKANISHI, T., SHINOMURA, Y. & MATSUZAWA, Y. (1993). Effect of endothelin 1 on ion transport in isolated rat colon. Gastroenterology 104, 1328-1336.
11. - secretion in human gut. Journal of Physiology 479, 433-440.
12. MACCUMBER, M., ROSS, C. A., GLASER, B. M. & SNYDER, S. H. (1989). Endothelin: visualization of mRNAs by in situ hybridization provides evidence for local action. Proceedings of the National Academy of Sciences of the USA 86, 7285-7289.
13. MADARA, J. L. & PAPPENHEIMER, J. R. (1987). Structural basis for physiological regulation of paracellular pathways in intestinal epithelia. Journal of Membrane Biology 100, 149-164.
14. MOUMMI, C., XIE, Y., KACHUR, J. F. & GAGINELLA, T. S. (1992). Endothelin-1 stimulates contraction and ion transport in the rat colon: different mechanisms of action. Journal of Pharmacology and Experimental Therapeutics 262, 409-414.
15. MURCH, S. H., BRAEGGER, C. P., SESSA, W. C. & MACDONALD, T. T. (1992). High endothelin-1 immunoreactivity in Crohn's disease and ulcerative colitis. Lancet 339, 381-385.
16. O'LOUGHLIN, E. V., HUNT, D. M., BOSTROM, T. E., HUNTER, D., GASKIN, K. J., GYÖRY, A. & COCKAYNE, D. J. H. (1996). X-ray microanalysis of cell elements in normal and cystic fibrosis jejunum: evidence for chloride secretion in villi. Gastroenterology 110, 411-418.
17. RODEN, M., PLASS, H., VIERHAPPER, H. & TURNHEIM, K. (1992). Endothelin-1 stimulates chloride and potassium secretion in rabbit descending colon. Pflügers Archiv 421, 163-167.
18. RUBANYI, G. M. & POLOKOFF, M. A. (1994). Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacological Reviews 46, 325-415.
19. SCHULTZ, S. G. & ZALUSKY, R. (1964). Ion transport in isolated rabbit ileum. Journal of General Physiology 47, 567-584.
20. SESSA, W. C., KAW, S., HECKER, M. & VANE, J. R. (1991). The biosynthesis of endothelin-1 by human polymorphonuclear leucocytes. Biochemical and Biophysical Research Communications 174, 613-618.
21. SUGIURA, M., INAGAMI, T. & KON, V. (1989). Endotoxin stimulates endothelin-release in vivo and in vitro as determined by radioimmunoassay. Biochemical and Biophysical Research Communications 161, 1220-1227.
22. TAKAHASHI, K., JONES, P. M., KANSE, S. M., LAM, H.-C., SPOKES, R. A., GHATEI, M. A. & BLOOM, S. R. (1990). Endothelin in the gastrointestinal tract: Presence of endothelin-like immunoreactivity, endothelin-1 messengerRNA, endothelin receptors, and pharmacological effect. Gastroenterology 99, 1660-1667.
23. +/glucose cotransporter. Annual Review of Physiology 55, 575-589.
24. YANAGISAVVA, M., KURIHARA, M., KIMURA, S., TOMOBE, Y., KOBAYASHI, M., MITSUI, Y., YAZAKI, Y. & GOTO, M. (1988). A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332, 411-415.
25. YOSHIZUMI, M., KURIHARA, H., MIRITA, T., YAMASHITA, T., OH-HASHI, Y., SUGIYAMA, T., TAKAKU, F., YANAGISAWA, M., MASAKI, T. & YAZAKI, Y. (1990). Interleukin-1 increases the production of endothelin-1 by cultured endothelial cells. Biochemical and Biophysical Research Communications 166, 324-329.