Beta-carotene did not work: Aftermath of the ATBC study

Cancer Letters

Volumn 114, Issue 1-2, 1997, Pages 235-236

  Rautalahti, Matti ^a   Albanes, Demetrius ^b   Virtamo, Jarmo ^a   Taylor, Philip R ^b   Huttunen, Jussi K ^a   Heinonen, Olli P ^a  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Cancer; Carotene; Epidemiology; Intervention; Smoking

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; BETA CAROTENE;

ADULT; AGED; CARCINOGENESIS; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; DOUBLE BLIND PROCEDURE; FOLLOW UP; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VITAMIN INTAKE;

AGED; BETA CAROTENE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASMS; SMOKING; VITAMIN E;

EID: 0030889563     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(97)04672-7     Document Type: Conference Paper

References (5)

1. The ATBC Cancer Prevention Study Group (1994) The alpha-tocopherol, beta-carotene lung cancer prevention study: design, methods, participant characteristics, and compliance. Ann. Epidemiol., 4, 1-9.
2. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study Group (1994) The effect of vitamin E and beta-carotene on the incidence of lung cancer and other cancers in male smokers. N. Engl. J. Med., 330, 1029.
3. Albanes, D., Heinonen, O.P., Taylor, P.R., Virtamo, J., Edwards, B.K., Rautalahti, M., Hartman, A.M., Palmgren, J., Freedman, L.S., Haapakoski, J., Barrett, M.J., Pietinen, P., Malila, N., Tala, E., Lippo, K., Salomaa, E.R., Tangrea, J.A., Teppo, L., Askin, F.B., Taskinen, E., Erozan, Y., Greenwald, P. and Huttunen, J.K. (1996) Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study: effects of base-line characteristics and study compliance, J. Natl. Cancer Inst., 88 (21), 1560-1570.
4. Omenn, G.S., Goodman, G.E., Thornquist, M.D., Balmes, J., Cullen, M.R., Glass, A., Keogh, J.P., Meyskens, F.L., Valanis, B., Williams, J.H., Barnhart, S. and Hammar, S. (1996) Effects of a combination of beta-carotene and vitamin A on lung cancer and cardiovascular disease, N. Engl. J. Med., 334 (18), 1150-1155.
5. Hennekens, C.H., Buring, J.E., Manson, J.E., Stampfer, M., Rosner, B., Cook, N.R., Belanger, C., LaMotte, F., Gaziano, J.M., Ridker, P.M., Willett, W. and Peto, R. (1996) Lack of effect of long-term supplementation with beta-carotene on the incidence of malignant neoplasms and cardiovascular disease, N. Engl. J. Med., 334 (18), 1145-1149.