Neuro-psychiatric effects of antimalarials

European Journal of Clinical Pharmacology

Volumn 52, Issue 1, 1997, Pages 1-6

  Van Riemsdijk, M M ^a   Van Der Klauw, M M ^b   Van Heest, J A C ^b   Reedeker, F R ^c   Ligthelm, R J ^c   Herings, R M C ^d   Stricker, B H Ch ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b Drug Safety Unit   (Netherlands)

^c Travel Clinic   (Netherlands)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

antimalarial drugs; cohort study; mefloquine; proguanil; psychic adverse effects

Indexed keywords

ANTIMALARIAL AGENT; MEFLOQUINE; PROGUANIL;

ADULT; AGITATION; ANXIETY NEUROSIS; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HEART PALPITATION; HUMAN; INSOMNIA; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; MOUTH ULCER; NEUROTOXICITY; NIGHTMARE; PRIORITY JOURNAL; QUESTIONNAIRE; VERTIGO;

ADULT; AKATHISIA, DRUG-INDUCED; ANTIMALARIALS; ANXIETY; CHLOROGUANIDE; CONFUSION; DEPRESSION; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; MALE; MEFLOQUINE; NEUROPSYCHOLOGICAL TESTS; PROSPECTIVE STUDIES; QUESTIONNAIRES; SLEEP INITIATION AND MAINTENANCE DISORDERS;

EID: 0030889095     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050240     Document Type: Article

References (24)

1. Hennequin C, Bouree P, Bazin N, Bisaro F, Feline A (1994) Severe psychiatric side effects observed during prophylaxis and treatment with mefloquine. Arch Int Med 154: 2360-2362
2. Stuiver PC, Ligthelm RJ, Goud TJ, (1989) Acute psychosis after mefloquine. Lancet ii: 282
3. Bjoerkman A, (1989) Acute psychosis following mefloquine prophylaxis. Lancet ii: 865
4. Stuerchler D, Handschin J, Kaiser D, Kerr L. Mittelholzer ML, Reber R, Fernex M, (1990) Neuropsychiatric side effects of mefloquine. N Eng J Med 322: 1752-1753
5. De Gennes C, Colas C, Nollet D, Le Thi Huong Du, Cacoub P. Piette JC, Godeau P, (1991) Attaque de panique au decours d'un traitement curatif par mefloquine. Ann Med Intern 142: 631
6. Caillon E, Schmitt L, Moron P (1992) Acute depressive symptoms after mefloquine treatment. Am J Psych 149: 712
7. Bem JL, Kerr L, Stuerchler D (1992) Mefloquine prophylaxis: an overview of spontaneous reports of severe psychiatric reactions and convulsions. J Trop Med Hyg 95: 167-179
8. Folkerts H, Kuhs H (1992) Psychotische Episode infolge Malariaprophylaxe mit Mefloquin. Eine kasuistische Mitteilung. Nervenarzt 63: 300-302
9. Bernardo M, Parellada E (1994) Mefloquina y reaccion psiquiatrica grave. Med Clin 102: 596
10. Marsepoil T, Petithory J, Faucher JM, Ho P, Viriot E, Benaiche F (1993) Encephalopathie et troubles mnesiques au cours des traitements par la mefloquine. Rev Med Int 14: 788-791
11. Wittes RC, Saginur R, (1995) Adverse reaction to mefloquine associated with ethanol ingestion. Can Med Assoc J 152: 515-517
12. Hollweg M, Soyka M, Greil W (1995) Mefloquininduzierte Psychosen. Probleme der Kausalzuordnung anhand zweier kasuistischer Berichte. Psych Prax 22: 33-36
13. Sowunmi A (1994) Acute psychosis after mefloquine: a case report. East Afr Med J 71: 818-819
14. McNair DM, Lorr M, Droppelman LF. (1981) Manual for the Profile of Mood States. Educational and Industrial Science. San Diego
15. Kahn HA, Sempos CT, (1991) Statistical methods in epidemiology, 2nd ed. Oxford University Press
16. Weinke T, Trautmann M, Held T, Weber G, Eichenlaub D, Fleischer K, Kern W, Pohle H, (1991) Neuropsychiatric side effects after the use of mefloquine. Am J Trop Med Hyg 45: 86-91
17. Steffen R, Fuchs E, Schildknecht J, Naef U, Funk M, Schlagenhauf P, Philips-Howard P, Stürchler D, (1993) Mefloquine compared with other malaria chemoprophylactic regimens in tourists visiting East Africa. Lancet 341: 1299-1303
18. Boudreau E, Schuster B, Sanchez J, Novakowski W, Johnson R, Redmond D, Hanson R, Dausel L, (1993) Tolerability of prophylactic Lariam Regimens. Trop Med Parasit 44: 257-265.
19. Lim LY, Go ML, (1985) The anticholinesterase activity of mefloquine. Clin Exp Pharmacol Phys 12: 527-531
20. Ngiam TL, Go ML, (1987) Stereospecific inhibition of cholinesterases by mefloquine enantiomers. Chem Pharm Bull 35: 409-412
21. Hoover DB, (1994) Cholinesterases and cholinesterase inhibitors. In: Craig CR, Stitzel RE (eds) Human Pharmacology 4th edn. Little. Brown & Co. Boston, pp 161-168
22. Van Riemsdijk MM, van der Klauw MM; Pepplinkhuizen L, Stricker BHCh, Psychic effects to mefloquine. Submitted.
23. Palmer KJ, Holliday SM, Brogden RN, (1993) Meflfoquine. A review of its antimalarial activity, pharmacokinetic properties and therapeutic efficacy. Drugs 45;(3):430-475
24. Inspectorate for Health Care. New guidelines for malaria prophylaxis. Ned Tijdschr Geneeskd 1996; in press.