메뉴 건너뛰기




Volumn 3, Issue 3, 1997, Pages 347-355

Induction of apoptosis in multidrug-resistant and radiation-resistant acute myeloid leukemia cells by a recombinant fusion toxin directed against the human granulocyte macrophage colony-stimulating factor receptor

Author keywords

[No Author keywords available]

Indexed keywords

DIPHTHERIA TOXIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GROWTH FACTOR RECEPTOR; HYBRID PROTEIN;

EID: 0030889068     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (30)

References (89)
  • 2
    • 0003378623 scopus 로고
    • Acute myeloid leukemia in adults
    • J. F. Holland, E. Frei, R. C. Bast, D. W. Kufe, D. L. Morton, and R. R. Weichselbaum (eds.). Philadelphia: Lea & Febiger
    • Schiffer, C. A. Acute myeloid leukemia in adults. In: J. F. Holland, E. Frei, R. C. Bast, D. W. Kufe, D. L. Morton, and R. R. Weichselbaum (eds.), Cancer Medicine, p. 1907-1933. Philadelphia: Lea & Febiger, 1993.
    • (1993) Cancer Medicine , pp. 1907-1933
    • Schiffer, C.A.1
  • 3
    • 0027474456 scopus 로고
    • How cancer cells evade chemotherapy: Sixteenth Richard and Hinda Rosenthal Foundation Award lecture
    • Gottesman, M. M. How cancer cells evade chemotherapy: Sixteenth Richard and Hinda Rosenthal Foundation Award lecture. Cancer Res., 53: 747-754, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 747-754
    • Gottesman, M.M.1
  • 7
    • 0026531732 scopus 로고
    • Protein toxin inhibitors of protein synthesis
    • Perentesis, J. P., Miller, S. P., and Bodley, J. W. Protein toxin inhibitors of protein synthesis. Biofactors, 3: 173-184, 1992.
    • (1992) Biofactors , vol.3 , pp. 173-184
    • Perentesis, J.P.1    Miller, S.P.2    Bodley, J.W.3
  • 8
    • 0019333247 scopus 로고
    • ADP-ribosylation of elongation factor 2 by diphtheria toxin. Isolation and properties of the novel ribosyl-amino acid and its hydrolysis products
    • Van Ness, B. G., Howard, J. B., and Bodley, J. W. ADP-ribosylation of elongation factor 2 by diphtheria toxin. Isolation and properties of the novel ribosyl-amino acid and its hydrolysis products. J. Biol. Chem. 255: 10717-10720, 1980.
    • (1980) J. Biol. Chem. , vol.255 , pp. 10717-10720
    • Van Ness, B.G.1    Howard, J.B.2    Bodley, J.W.3
  • 9
    • 0026747170 scopus 로고
    • Expression cloning of a diphtheria toxin receptor: Identity with a heparin-binding EGF-like growth factor precursor
    • Naglich, J. G., Metherall, J. E., Russell, D. W., and Eidels, L. Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor. Cell, 69: 1051-1061, 1992.
    • (1992) Cell , vol.69 , pp. 1051-1061
    • Naglich, J.G.1    Metherall, J.E.2    Russell, D.W.3    Eidels, L.4
  • 10
    • 0024152695 scopus 로고
    • Structure-activity relationships in diphtheria toxin and Pseudomonas aeruginosa exotoxin A
    • Collier, R. J. Structure-activity relationships in diphtheria toxin and Pseudomonas aeruginosa exotoxin A. Cancer Treat. Res., 37: 25-35, 1988.
    • (1988) Cancer Treat. Res. , vol.37 , pp. 25-35
    • Collier, R.J.1
  • 11
    • 0020641115 scopus 로고
    • Cloned fragment A of diphtheria toxin is expressed and secreted into the periplasmic space of Escherichia coli K12
    • Leong, D., Coleman, K. D., and Murphy, J. R. Cloned fragment A of diphtheria toxin is expressed and secreted into the periplasmic space of Escherichia coli K12. Science (Washington DC), 220: 515-517, 1983.
    • (1983) Science (Washington DC) , vol.220 , pp. 515-517
    • Leong, D.1    Coleman, K.D.2    Murphy, J.R.3
  • 13
    • 0021778908 scopus 로고
    • The diphtheria toxin structural gene
    • Murphy, J. R. The diphtheria toxin structural gene. Curr. Top, Microbiol. Immunol., 118: 235-251, 1985.
    • (1985) Curr. Top, Microbiol. Immunol. , vol.118 , pp. 235-251
    • Murphy, J.R.1
  • 15
    • 0008530328 scopus 로고
    • Genetic construction, expression, and melanoma-selective cytotoxicity of a diphtheria toxin-related α-melanocyte-stimulating hormone fusion protein
    • Murphy, J. R., Bishai, W., Borowski, M., Miyanohara, A., Boyd, J., and Nagle, S. Genetic construction, expression, and melanoma-selective cytotoxicity of a diphtheria toxin-related α-melanocyte-stimulating hormone fusion protein. Proc. Natl. Acad. Sci. USA, 83: 8258-8262, 1986.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 8258-8262
    • Murphy, J.R.1    Bishai, W.2    Borowski, M.3    Miyanohara, A.4    Boyd, J.5    Nagle, S.6
  • 16
    • 0023529699 scopus 로고
    • Diphtheria toxin receptor binding domain substitution with interleukin-2: Genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein
    • Williams, D. P., Parker, K., Bacha, P., Bishai, W., Borowski, M., Genbauffe, F., Strom, T. B., and Murphy, J. R. Diphtheria toxin receptor binding domain substitution with interleukin-2: genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein. Protein Eng., 7: 493-498, 1987.
    • (1987) Protein Eng. , vol.7 , pp. 493-498
    • Williams, D.P.1    Parker, K.2    Bacha, P.3    Bishai, W.4    Borowski, M.5    Genbauffe, F.6    Strom, T.B.7    Murphy, J.R.8
  • 17
    • 0026328791 scopus 로고
    • Diphtheria toxin receptor-binding domain substitution with interleukin 6: Genetic construction and interleukin 6 receptor-specific action of a diphtheria toxin-related interleukin 6 fusion protein
    • Jean, L. F., and Murphy, J. R. Diphtheria toxin receptor-binding domain substitution with interleukin 6: genetic construction and interleukin 6 receptor-specific action of a diphtheria toxin-related interleukin 6 fusion protein. Protein Eng., 4: 989-994, 1991.
    • (1991) Protein Eng. , vol.4 , pp. 989-994
    • Jean, L.F.1    Murphy, J.R.2
  • 18
    • 0025745412 scopus 로고
    • Interleukin 4 receptor targeted cytotoxicity: Genetic construction and in vivo immunosuppressive activity of a diphtheria toxin-related m urine interleukin 4 fusion protein
    • Lakkis, F., Steele, A., Pacheco-Silva, A., Rubin-Kelley, V., Strom, T. B., and Murphy, J. R. Interleukin 4 receptor targeted cytotoxicity: genetic construction and in vivo immunosuppressive activity of a diphtheria toxin-related m urine interleukin 4 fusion protein. Eur. J. Immunol., 21: 2253-2258, 1991.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2253-2258
    • Lakkis, F.1    Steele, A.2    Pacheco-Silva, A.3    Rubin-Kelley, V.4    Strom, T.B.5    Murphy, J.R.6
  • 20
    • 0028204771 scopus 로고
    • Domain swapping: Entangling alliances between proteins
    • Bennett, M. J., Choe, S., and Eisenberg, D. Domain swapping: entangling alliances between proteins. Proc. Natl. Acad. Sci. USA, 91: 3127-3131, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3127-3131
    • Bennett, M.J.1    Choe, S.2    Eisenberg, D.3
  • 21
    • 0026320870 scopus 로고
    • Novel fold and putative receptor binding site of granulocyte-macrophage colony-stimulating factor
    • Diederichs, K., Boone, T., and Karplus, P. A. Novel fold and putative receptor binding site of granulocyte-macrophage colony-stimulating factor. Science (Washington DC), 254: 1779-1782, 1991.
    • (1991) Science (Washington DC) , vol.254 , pp. 1779-1782
    • Diederichs, K.1    Boone, T.2    Karplus, P.A.3
  • 22
    • 0026520373 scopus 로고
    • Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor
    • Walter, M. R., Cook, W. J., Ealick, S. E., Nagabhushan, T. L., Trotta, P. P., and Bugg, C. E. Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor. J. Mol. Biol., 224: 1075-1085, 1992.
    • (1992) J. Mol. Biol. , vol.224 , pp. 1075-1085
    • Walter, M.R.1    Cook, W.J.2    Ealick, S.E.3    Nagabhushan, T.L.4    Trotta, P.P.5    Bugg, C.E.6
  • 23
    • 0025162844 scopus 로고
    • Structural design and molecular evolution of a cytokine receptor superfamily
    • Bazan, J. F. Structural design and molecular evolution of a cytokine receptor superfamily. Proc. Natl. Acad. Sci. USA, 87: 6934-6938, 1990.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 6934-6938
    • Bazan, J.F.1
  • 25
    • 0026059811 scopus 로고
    • Production of a pokeweed antiviral protein (PAP)-containing immunotoxin, B43-PAP, directed against the CD 19 human B lineage lymphoid differentiation antigen in highly purified form for human clinical trials
    • Myers, D. E., Irvin, J. D., Smith, R. S., Kuebelbeck, V. M., and Uckun, F. M. Production of a pokeweed antiviral protein (PAP)-containing immunotoxin, B43-PAP, directed against the CD 19 human B lineage lymphoid differentiation antigen in highly purified form for human clinical trials. J. Immunol. Methods, 136: 221-237, 1991.
    • (1991) J. Immunol. Methods , vol.136 , pp. 221-237
    • Myers, D.E.1    Irvin, J.D.2    Smith, R.S.3    Kuebelbeck, V.M.4    Uckun, F.M.5
  • 26
    • 0023605430 scopus 로고
    • The HL-60 promyelocytic leukemia cell line: Proliferation, differentiation, and cellular oncogene expression
    • Collins, S. J. The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression. Blood, 70: 1233-1244, 1987.
    • (1987) Blood , vol.70 , pp. 1233-1244
    • Collins, S.J.1
  • 27
    • 0016640079 scopus 로고
    • Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome
    • Lozzio, C. B., Lozzio, B. B. Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. Blood, 45: 321-334, 1975.
    • (1975) Blood , vol.45 , pp. 321-334
    • Lozzio, C.B.1    Lozzio, B.B.2
  • 28
    • 0024415437 scopus 로고
    • Mechanisms of multidrug resistance in HL60 cells. Analysis of resistance associated membrane proteins and levels of mdr gene expression
    • McGrath, T., Latoud, C., Arnold, S. T., Safa, A. R., Felsted, R. L., and Center, M. S. Mechanisms of multidrug resistance in HL60 cells. Analysis of resistance associated membrane proteins and levels of mdr gene expression. Biochem. Pharmacol., 38: 3611-3619, 1989.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 3611-3619
    • McGrath, T.1    Latoud, C.2    Arnold, S.T.3    Safa, A.R.4    Felsted, R.L.5    Center, M.S.6
  • 29
    • 0022458951 scopus 로고
    • Isolation and characterization of adriamycin-resistam HL-60 cells which are not defective in the initial intracellular accumulation of drug
    • Marsh, W., Sicheri, D., and Center, M. S. Isolation and characterization of adriamycin-resistam HL-60 cells which are not defective in the initial intracellular accumulation of drug. Cancer Res., 46: 4053-4057, 1986.
    • (1986) Cancer Res. , vol.46 , pp. 4053-4057
    • Marsh, W.1    Sicheri, D.2    Center, M.S.3
  • 30
    • 0027249710 scopus 로고
    • The MRP gene associated with a non-P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein
    • Krishnamachary, N., and Center, M. S. The MRP gene associated with a non-P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein. Cancer Res., 53: 3658-3661, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 3658-3661
    • Krishnamachary, N.1    Center, M.S.2
  • 31
    • 0028178981 scopus 로고
    • A circularly permuted recombinant interleukin 4 toxin with increased activity
    • Kreitman, R. J., Puri, R. K., and Pastan, I. A circularly permuted recombinant interleukin 4 toxin with increased activity. Proc. Natl. Acad. Sci. USA, 91: 6889-6893, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6889-6893
    • Kreitman, R.J.1    Puri, R.K.2    Pastan, I.3
  • 33
    • 0029838226 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase as a mediator of radiation-induced apoptosis in B-lineage lymphoid cells
    • Uckun, F. M., Waddick, K. G., Mahajan, S., Jun, X., Takata, M., Bolen, J., and Kurosak, T. Bruton's tyrosine kinase as a mediator of radiation-induced apoptosis in B-lineage lymphoid cells. Science (Washington DC), 273: 1096-1100, 1996.
    • (1996) Science (Washington DC) , vol.273 , pp. 1096-1100
    • Uckun, F.M.1    Waddick, K.G.2    Mahajan, S.3    Jun, X.4    Takata, M.5    Bolen, J.6    Kurosak, T.7
  • 34
    • 0022443639 scopus 로고
    • Characterization of the cell surface receptor for human granulocyte/macrophage colonystimulating factor
    • Park, L. S., Friend, D., Gillis, S., and Urdal, D. L. Characterization of the cell surface receptor for human granulocyte/macrophage colonystimulating factor. J. Exp. Med., 164: 251-262, 1986.
    • (1986) J. Exp. Med. , vol.164 , pp. 251-262
    • Park, L.S.1    Friend, D.2    Gillis, S.3    Urdal, D.L.4
  • 35
    • 0027265538 scopus 로고
    • DNA fragmentation and cytolysis in U937 cells treated with diphtheria toxin or other inhibitors of protein synthesis
    • Kochi, S. K., and Collier, R. J. DNA fragmentation and cytolysis in U937 cells treated with diphtheria toxin or other inhibitors of protein synthesis. Exp. Cell Res, 208: 296-302, 1993.
    • (1993) Exp. Cell Res , vol.208 , pp. 296-302
    • Kochi, S.K.1    Collier, R.J.2
  • 36
    • 0025185463 scopus 로고
    • Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis
    • Martin, S. J, Lennon, S. V., Bonham, A. M., and Cotter, T. G. Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis. J. Immunol., 145: 1859-1867, 1990.
    • (1990) J. Immunol. , vol.145 , pp. 1859-1867
    • Martin, S.J.1    Lennon, S.V.2    Bonham, A.M.3    Cotter, T.G.4
  • 37
    • 0026669469 scopus 로고
    • P53 function and dysfunction
    • Vogelstein, B., Kinzler, K. W. p53 function and dysfunction. Cell, 70: 523-526, 1992.
    • (1992) Cell , vol.70 , pp. 523-526
    • Vogelstein, B.1    Kinzler, K.W.2
  • 38
    • 0027489384 scopus 로고
    • Clinical implications of the p53 tumor-suppressor gene
    • Harris, C. C., and Hollstein, M. Clinical implications of the p53 tumor-suppressor gene. New Engl. J. Med., 329: 1318-1327, 1993.
    • (1993) New Engl. J. Med. , vol.329 , pp. 1318-1327
    • Harris, C.C.1    Hollstein, M.2
  • 40
    • 0027263181 scopus 로고
    • Clinical significance of P-glycoprotein in multidrug resistance malignancies
    • Arceci, R. J. Clinical significance of P-glycoprotein in multidrug resistance malignancies. Blood, 81: 2215-2222, 1993.
    • (1993) Blood , vol.81 , pp. 2215-2222
    • Arceci, R.J.1
  • 41
    • 0028149617 scopus 로고
    • P-glycopro-tein-mediated multidrug resistance in normal and neoplastic hematopoietic cells
    • Licht, T., Pastan, I., Gottesman, M., and Herrmann, F. P-glycoprotein-mediated multidrug resistance in normal and neoplastic hematopoietic cells. Ann. Hematol., 69: 159-171, 1994.
    • (1994) Ann. Hematol. , vol.69 , pp. 159-171
    • Licht, T.1    Pastan, I.2    Gottesman, M.3    Herrmann, F.4
  • 42
    • 0024329881 scopus 로고
    • The biochemistry of P-glycoproteinmediated multidrug resistance
    • Endicott, J. A., and Ling, V. The biochemistry of P-glycoproteinmediated multidrug resistance. Annu. Rev. Biochem. 58: 137-171, 1989.
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 137-171
    • Endicott, J.A.1    Ling, V.2
  • 43
    • 0021952694 scopus 로고
    • Isolation and characterization of an anthracycline-resistant human leukemic cell line
    • Bhalla, K., Hindenburg, A., Taub. R. N., and Grant, S. Isolation and characterization of an anthracycline-resistant human leukemic cell line. Cancer Res., 45: 3657-3662, 1985.
    • (1985) Cancer Res. , vol.45 , pp. 3657-3662
    • Bhalla, K.1    Hindenburg, A.2    Taub, R.N.3    Grant, S.4
  • 45
    • 0026602155 scopus 로고
    • Clinical significance of multidrug resistance P-glycoprotein expression on acute nonlymphoblastic leukemia cells at diagnosis
    • Campos, L., Guyotat, D., Archimbaud, E., Calmard-Oriol, P., Tsuruo, T., Troncy, J., Treille, D. and Fiere, D. Clinical significance of multidrug resistance P-glycoprotein expression on acute nonlymphoblastic leukemia cells at diagnosis. Blood, 79: 473-476, 1992.
    • (1992) Blood , vol.79 , pp. 473-476
    • Campos, L.1    Guyotat, D.2    Archimbaud, E.3    Calmard-Oriol, P.4    Tsuruo, T.5    Troncy, J.6    Treille, D.7    Fiere, D.8
  • 46
    • 0026065655 scopus 로고
    • High risk of early resistant relapse for leukaemic patients with presence of multidrug resistance associated P-glycoprotein positive cells in complete remission
    • Musto, P., Melillo, L., Lombardi, G., Matera, R., di Giorgio, G., and Carotenuto, M. High risk of early resistant relapse for leukaemic patients with presence of multidrug resistance associated P-glycoprotein positive cells in complete remission. Br. J. Haematol., 77: 50-53, 1991.
    • (1991) Br. J. Haematol. , vol.77 , pp. 50-53
    • Musto, P.1    Melillo, L.2    Lombardi, G.3    Matera, R.4    Di Giorgio, G.5    Carotenuto, M.6
  • 48
    • 0025914062 scopus 로고
    • Multidrug resistance (mdr1) gene expression in adult acute leukemias: Correlations with treatment outcome and in vitro drug sensitivity
    • Marie, J. P., Zittoun, R., Sikic, B. I. Multidrug resistance (mdr1) gene expression in adult acute leukemias: correlations with treatment outcome and in vitro drug sensitivity. Blood, 78: 586-592, 1991.
    • (1991) Blood , vol.78 , pp. 586-592
    • Marie, J.P.1    Zittoun, R.2    Sikic, B.I.3
  • 51
    • 0028794758 scopus 로고
    • Increased expression of the multidrug resistance-associated protein gene in relapsed acute leukemia
    • Schneider, E., Cowan, K. H., Bader, H., Toomey, S., Schwanz, G. N., Karp, J. E., Burke, P. J., Kaufmann, S. H. Increased expression of the multidrug resistance-associated protein gene in relapsed acute leukemia. Blood, 85: 186-193, 1995.
    • (1995) Blood , vol.85 , pp. 186-193
    • Schneider, E.1    Cowan, K.H.2    Bader, H.3    Toomey, S.4    Schwanz, G.N.5    Karp, J.E.6    Burke, P.J.7    Kaufmann, S.H.8
  • 52
    • 0028081258 scopus 로고
    • Expression of the multidrug resistance associated protein and P-glycoprotein in doxorubicin-selected human myeloid leukemia cells
    • Slapak, C. A., Mizunuma, N., and Kufe, D. W. Expression of the multidrug resistance associated protein and P-glycoprotein in doxorubicin-selected human myeloid leukemia cells. Blood, 84: 3113-3121, 1994.
    • (1994) Blood , vol.84 , pp. 3113-3121
    • Slapak, C.A.1    Mizunuma, N.2    Kufe, D.W.3
  • 53
    • 0027518576 scopus 로고
    • Autonomous proliferation of leukemic cells in vitro as a determinant of prognosis in adult acute myeloid leukemia
    • Lowenberg, B., van Putten, W. L., Touw, I. P., Deiwel, R., and Santini, V. Autonomous proliferation of leukemic cells in vitro as a determinant of prognosis in adult acute myeloid leukemia. New Engl. J. Med., 328: 614-619, 1993.
    • (1993) New Engl. J. Med. , vol.328 , pp. 614-619
    • Lowenberg, B.1    Van Putten, W.L.2    Touw, I.P.3    Deiwel, R.4    Santini, V.5
  • 54
    • 0027185541 scopus 로고
    • Autonomous growth of blast cells is associated with reduced survival in acute myeloblastic leukemia
    • Hunter, A. E., Rogers, S. Y., Roberts, I. A., Barrett, A. J., and Russell, N. Autonomous growth of blast cells is associated with reduced survival in acute myeloblastic leukemia. Blood, 82: 899-903, 1993.
    • (1993) Blood , vol.82 , pp. 899-903
    • Hunter, A.E.1    Rogers, S.Y.2    Roberts, I.A.3    Barrett, A.J.4    Russell, N.5
  • 55
    • 0022811277 scopus 로고
    • Autocrine secretion of GM-CSF in acute myeloblastic leukemia
    • Young, D. C., and Griffin, J. D. Autocrine secretion of GM-CSF in acute myeloblastic leukemia. Blood, 68: 1178-1181, 1986.
    • (1986) Blood , vol.68 , pp. 1178-1181
    • Young, D.C.1    Griffin, J.D.2
  • 56
    • 0023108264 scopus 로고
    • Constitutive expression of the granulocyte-macrophage colony-stimulating factor gene in acute myeloblastic leukemia
    • Young, D. C., Wagner, K., and Griffin, J. D. Constitutive expression of the granulocyte-macrophage colony-stimulating factor gene in acute myeloblastic leukemia. J. Clin. Invest., 79: 100-106, 1987.
    • (1987) J. Clin. Invest. , vol.79 , pp. 100-106
    • Young, D.C.1    Wagner, K.2    Griffin, J.D.3
  • 57
    • 0026673959 scopus 로고
    • Autocrine growth factors and leukaemic haemopoiesis
    • Russell, N. H. Autocrine growth factors and leukaemic haemopoiesis. Blood Rev., 6: 149-156, 1992.
    • (1992) Blood Rev. , vol.6 , pp. 149-156
    • Russell, N.H.1
  • 58
    • 0023626214 scopus 로고
    • Secretion of interleukin-1 by acute myeloblastic leukemia cells in vitro induces endothelial cells to secrete colony stimulating factors
    • Griffin, J. D., Rambaldi, A., Vellenga, E., Young, D. C., Ostapovicz, D., and Cannistra, S. A. Secretion of interleukin-1 by acute myeloblastic leukemia cells in vitro induces endothelial cells to secrete colony stimulating factors. Blood, 70: 1218-1221, 1987.
    • (1987) Blood , vol.70 , pp. 1218-1221
    • Griffin, J.D.1    Rambaldi, A.2    Vellenga, E.3    Young, D.C.4    Ostapovicz, D.5    Cannistra, S.A.6
  • 59
    • 0026635199 scopus 로고
    • Role of autocrine and paracrine production of granulocyte-macrophage colony-stimulating factor and interleukin-1 beta in the autonomous growth of acute myeloblastic leukaemia cells-studies using purified CD34-positive cells
    • Bradbury, D., Rogers, S., Reilly, I. A., Kozlowski, R., and Russell, N. H. Role of autocrine and paracrine production of granulocyte-macrophage colony-stimulating factor and interleukin-1 beta in the autonomous growth of acute myeloblastic leukaemia cells-studies using purified CD34-positive cells. Leukemia (Baltimore), 6: 562-566, 1992.
    • (1992) Leukemia (Baltimore) , vol.6 , pp. 562-566
    • Bradbury, D.1    Rogers, S.2    Reilly, I.A.3    Kozlowski, R.4    Russell, N.H.5
  • 60
    • 0025162089 scopus 로고
    • Endogenous interleukin-1 can regulate the autonomous growth of the blast cells of acute myeloblastic leukemia by inducing autocrine secretion of GM-CSF
    • Bradbury, D., Bowen, G., Kozlowski, R., Reilly, I., and Russell, N. Endogenous interleukin-1 can regulate the autonomous growth of the blast cells of acute myeloblastic leukemia by inducing autocrine secretion of GM-CSF. Leukemia (Baltimore), 4: 44-47, 1990.
    • (1990) Leukemia (Baltimore) , vol.4 , pp. 44-47
    • Bradbury, D.1    Bowen, G.2    Kozlowski, R.3    Reilly, I.4    Russell, N.5
  • 61
    • 0027983682 scopus 로고
    • Evidence for internal autocrine regulation of growth in acute myeloblastic leukemia cells
    • Rogers, S. Y., Bradbury, D., Kozlowski, R., and Russell, N. H. Evidence for internal autocrine regulation of growth in acute myeloblastic leukemia cells. Exp. Hematol., 22: 593-598, 1994.
    • (1994) Exp. Hematol. , vol.22 , pp. 593-598
    • Rogers, S.Y.1    Bradbury, D.2    Kozlowski, R.3    Russell, N.H.4
  • 62
    • 0024360582 scopus 로고
    • Interleukin-3 and granulocyte-monocyte colony-stimulating factor receptors on human acute myelocytic leukemia cells and relationship to the proliferative response
    • Budel, L. M., Touw, I. P., Delwel, R., Clark, S. C., and Lowenberg, B. Interleukin-3 and granulocyte-monocyte colony-stimulating factor receptors on human acute myelocytic leukemia cells and relationship to the proliferative response. Blood, 74: 565-571, 1989.
    • (1989) Blood , vol.74 , pp. 565-571
    • Budel, L.M.1    Touw, I.P.2    Delwel, R.3    Clark, S.C.4    Lowenberg, B.5
  • 63
    • 0024333958 scopus 로고
    • Interleukin-3, GM-CSF, and G-CSF receptor expression on cell lines and primary leukemia cells: Receptor heterogeneity and relationship to growth factor responsiveness
    • Park, L. S., Waldron, P. E., Friend, D., Sassenfeld, H. M., Price, V., Anderson, D., Cosman, D., Andrews, R. G., Bernstein, I. D., and Urdal, D. L. Interleukin-3, GM-CSF, and G-CSF receptor expression on cell lines and primary leukemia cells: receptor heterogeneity and relationship to growth factor responsiveness. Blood, 74: 56-65, 1989.
    • (1989) Blood , vol.74 , pp. 56-65
    • Park, L.S.1    Waldron, P.E.2    Friend, D.3    Sassenfeld, H.M.4    Price, V.5    Anderson, D.6    Cosman, D.7    Andrews, R.G.8    Bernstein, I.D.9    Urdal, D.L.10
  • 64
    • 0025291990 scopus 로고
    • IL-3 inhibits the binding of GM-CSF to AML blasts, but the two cytokines act synergistically in supporting blast proliferation
    • Onetto-Pothier, N., Aumont, N., Haman, A., Park, L., Clark, S. C., De Lean, A., and Hoang, T. IL-3 inhibits the binding of GM-CSF to AML blasts, but the two cytokines act synergistically in supporting blast proliferation. Leukemia, 4: 329-336, 1990.
    • (1990) Leukemia , vol.4 , pp. 329-336
    • Onetto-Pothier, N.1    Aumont, N.2    Haman, A.3    Park, L.4    Clark, S.C.5    De Lean, A.6    Hoang, T.7
  • 65
    • 0025092244 scopus 로고
    • Characterization of granulocyte-macrophage colony-stimulating factor receptor on the blast cells of acute myeloblastic leukemia
    • Onetto-Pothier, N., Aumont, N., Haman, A., Bigras, C., Wong, G. G., Clark, S. C., De Lean, A., and Hoang, T. Characterization of granulocyte-macrophage colony-stimulating factor receptor on the blast cells of acute myeloblastic leukemia. Blood, 75: 59-66, 1990.
    • (1990) Blood , vol.75 , pp. 59-66
    • Onetto-Pothier, N.1    Aumont, N.2    Haman, A.3    Bigras, C.4    Wong, G.G.5    Clark, S.C.6    De Lean, A.7    Hoang, T.8
  • 67
    • 0027059340 scopus 로고
    • Treatment of de novo acute myelogenous leukemia with recombinant granulocyte macrophage-colony-stimulating factor in combination with standard induction chemotherapy: Effect of granulocyte macrophage-colony-stimulating factor on white blood cell counts
    • Valent, P., Sillaber, C., Geissler, K., Andreeff, M., Tafuri, A., Vieder, L., Schulz, G., Lechner, K., and Bettelheim, P. Treatment of de novo acute myelogenous leukemia with recombinant granulocyte macrophage-colony-stimulating factor in combination with standard induction chemotherapy: effect of granulocyte macrophage-colony-stimulating factor on white blood cell counts. Med. Pediatr. Oncoi., 2 (Suppl.): 18-22, 1992.
    • (1992) Med. Pediatr. Oncoi. , vol.2 , Issue.SUPPL. , pp. 18-22
    • Valent, P.1    Sillaber, C.2    Geissler, K.3    Andreeff, M.4    Tafuri, A.5    Vieder, L.6    Schulz, G.7    Lechner, K.8    Bettelheim, P.9
  • 69
    • 0024600738 scopus 로고
    • Granulocytemacrophage colony-stimulating factor enhances the cytotoxic effects of cytosine arabinoside in acute myeloblastic leukemia and in the myeloid blast crisis phase of chronic myeloid leukemia
    • Cannistra, S. A., Groshek, P., and Griffin, J. D. Granulocytemacrophage colony-stimulating factor enhances the cytotoxic effects of cytosine arabinoside in acute myeloblastic leukemia and in the myeloid blast crisis phase of chronic myeloid leukemia. Leukemia (Baltimore), 3: 328-334, 1989.
    • (1989) Leukemia (Baltimore) , vol.3 , pp. 328-334
    • Cannistra, S.A.1    Groshek, P.2    Griffin, J.D.3
  • 70
    • 0025893903 scopus 로고
    • Simultaneous administration of gran ulocyte-macrophage colony-stimulating factor and cytosine arabinoside for the treatment of relapsed acute myeloid leukemia
    • Cannistra, S. A., DiCarlo, J., Groshek, P., Kanakura, Y., Berg, D., Mayer, R. J., and Griffin, J. D. Simultaneous administration of gran ulocyte-macrophage colony-stimulating factor and cytosine arabinoside for the treatment of relapsed acute myeloid leukemia. Leukemia (Baltimore), 5: 230-238, 1991.
    • (1991) Leukemia (Baltimore) , vol.5 , pp. 230-238
    • Cannistra, S.A.1    DiCarlo, J.2    Groshek, P.3    Kanakura, Y.4    Berg, D.5    Mayer, R.J.6    Griffin, J.D.7
  • 71
    • 0026716934 scopus 로고
    • Treatment of newly diagnosed acute myelogenous leukemia with granulocyte-macrophage colony-stimulating factor (GM-CSF) before and during continuous-infusion high-dose ara-C + daunorubicin: Comparison to patients treated without GM-CSF
    • Estey, E., Thall, P. F., Kantarjian, H., O'Brien, S., Koller, C. A., Beran, M., Gutterman, J., Deisseroth, A., and Keating, M. Treatment of newly diagnosed acute myelogenous leukemia with granulocyte-macrophage colony-stimulating factor (GM-CSF) before and during continuous-infusion high-dose ara-C + daunorubicin: comparison to patients treated without GM-CSF. Blood, 79: 2246-2255, 1992.
    • (1992) Blood , vol.79 , pp. 2246-2255
    • Estey, E.1    Thall, P.F.2    Kantarjian, H.3    O'Brien, S.4    Koller, C.A.5    Beran, M.6    Gutterman, J.7    Deisseroth, A.8    Keating, M.9
  • 72
    • 0029383661 scopus 로고
    • Targeting Pseudomonas exotoxin to hematologic malignancies
    • Kreitman, R. J., and Pastan, I. Targeting Pseudomonas exotoxin to hematologic malignancies. Semin. Cancer Biol., 6: 297-306, 1995.
    • (1995) Semin. Cancer Biol. , vol.6 , pp. 297-306
    • Kreitman, R.J.1    Pastan, I.2
  • 73
    • 0027218841 scopus 로고
    • Pseudomonas exotoxin and recombinant immunotoxins derived from it
    • Fitzgerald, D., and Pastan, I. Pseudomonas exotoxin and recombinant immunotoxins derived from it. Ann. NY Acad. Sci., 685: 740-145, 1993.
    • (1993) Ann. NY Acad. Sci. , vol.685 , pp. 740-1145
    • Fitzgerald, D.1    Pastan, I.2
  • 75
    • 0028025563 scopus 로고
    • Apoptosis in cancer therapy: Crossing the threshold
    • Fisher, D. E. Apoptosis in cancer therapy: crossing the threshold. Cell, 78: 539-542, 1994.
    • (1994) Cell , vol.78 , pp. 539-542
    • Fisher, D.E.1
  • 76
    • 0027479796 scopus 로고
    • Apoptosis (the 1992 Frank Rose Memorial Lecture)
    • Wyllie, A. H. Apoptosis (the 1992 Frank Rose Memorial Lecture). Br. J. Cancer, 67: 205-208, 1993.
    • (1993) Br. J. Cancer , vol.67 , pp. 205-208
    • Wyllie, A.H.1
  • 77
    • 0028939862 scopus 로고
    • The genetic regulation of apoptosis
    • Wyllie, A. H. The genetic regulation of apoptosis. Curr. Opin. Genet. & Dev., 5: 97-104, 1995.
    • (1995) Curr. Opin. Genet. & Dev. , vol.5 , pp. 97-104
    • Wyllie, A.H.1
  • 78
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson, C. B. Apoptosis in the pathogenesis and treatment of disease. Science (Washington DC), 267: 1456-1462, 1995.
    • (1995) Science (Washington DC) , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 79
    • 0027196547 scopus 로고
    • Control of programmed cell death in normal and leukemic cells: New implications for therapy
    • Sachs, L., and Lotem, J. Control of programmed cell death in normal and leukemic cells: new implications for therapy. Blood, 82: 15-21, 1993.
    • (1993) Blood , vol.82 , pp. 15-21
    • Sachs, L.1    Lotem, J.2
  • 80
    • 0025880971 scopus 로고
    • Drug-target interactions: Only the first step in the commitment lo a programmed cell death?
    • Dive, C., and Hickman, J. A. Drug-target interactions: only the first step in the commitment lo a programmed cell death? Br. J. Cancer, 64: 192-196, 1991.
    • (1991) Br. J. Cancer , vol.64 , pp. 192-196
    • Dive, C.1    Hickman, J.A.2
  • 81
    • 0028329172 scopus 로고
    • Apoptosis. Its significance in cancer and cancer therapy
    • Kerr, J. F., Wimerford, C. M., and Harmon, B. V. Apoptosis. Its significance in cancer and cancer therapy. Cancer (Phila.), 73: 2013-2026, 1994.
    • (1994) Cancer (Phila.) , vol.73 , pp. 2013-2026
    • Kerr, J.F.1    Wimerford, C.M.2    Harmon, B.V.3
  • 85
    • 0028955358 scopus 로고
    • P53 gene mutations in lymphoid diseases and their possible relevance to drug resistance
    • Newcomb, E. W. P53 gene mutations in lymphoid diseases and their possible relevance to drug resistance. Leuk. & Lymphoma, 17: 211-221, 1995.
    • (1995) Leuk. & Lymphoma , vol.17 , pp. 211-221
    • Newcomb, E.W.1
  • 86
    • 0028172868 scopus 로고
    • P53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies
    • Wattel, E., Preudhomme, C., Hecquet, B., Vanrumbeke, M., Quesnel, B., Dervite, I., Morel, P., and Fenaux, P. p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood, 84: 3148-3157, 1994.
    • (1994) Blood , vol.84 , pp. 3148-3157
    • Wattel, E.1    Preudhomme, C.2    Hecquet, B.3    Vanrumbeke, M.4    Quesnel, B.5    Dervite, I.6    Morel, P.7    Fenaux, P.8
  • 88
    • 0025201329 scopus 로고
    • Does diphtheria toxin have nuclease activity?
    • Johnson, V. G. Does diphtheria toxin have nuclease activity? Science (Washington DC), 250: 832-833, 1990.
    • (1990) Science (Washington DC) , vol.250 , pp. 832-833
    • Johnson, V.G.1
  • 89
    • 1842282749 scopus 로고
    • Does diphtheria toxin have nucleate activity?
    • Bodley, J. W. Does diphtheria toxin have nucleate activity? Science (Washington DC), 250: 833-834, 1990.
    • (1990) Science (Washington DC) , vol.250 , pp. 833-834
    • Bodley, J.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.