Effect of high glucose on synthesis and gene expression of collagen and fibronectin in cultured vascular smooth muscle cells

Experimental and Molecular Medicine

Volumn 29, Issue 1, 1997, Pages 59-64

  Ha, Sung Woo ^a   Seo, Ye Kyung ^a   Kim, Jung Guk ^a   Kim, In San ^a   Sohn, Kun Young ^a   Lee, Byung Heon ^b   Kim, Bo Wan ^a  

^a Kyungpook National University School of Medicine   (South Korea)

^b Dongguk University College of Medicine   (South Korea)

Author keywords

Atherosclerosis; Collagen; Diabetes mellitus; Fibronectin; High glucose; Vascular smooth muscle cell

Indexed keywords

COLLAGEN; FIBRONECTIN; GLUCOSE; MESSENGER RNA; PROCOLLAGEN;

ANIMAL CELL; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; GENE EXPRESSION REGULATION; MUSCLE FIBER CULTURE; NONHUMAN; PROTEIN SYNTHESIS REGULATION; RAT; VASCULAR SMOOTH MUSCLE;

ANIMALIA;

EID: 0030888693     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.1997.9     Document Type: Article

References (4)

1. Ayo, S. H., Radnik, R. A., Garoni, J. A., Glass II, W. F. and Kreisberg, J. I. (1990) High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells. Am. J. Pathol. 136: 1339-1348
2. Ayo, S. H., Radnik, R. A., Glass II, W. F., Garoni, J. A., Rampt, E. R., Appling, D. R. and Kreisberg, J. I. (1991) Increased extracellular matrix synthesis and mRNA in mesangial cells grown in high-glucose medium. Am. J. Physiol. 260: F185-F191
3. Barnes, M. J. (1988) Collagens of normal and diseased blood vessel wall. In Collagen (Nimni, M. E., ed.), Vol. I, pp. 275-290, CRC Press, Boca Raton
4. Chamley-Campbell, J. H. and Campbell, G. R. (1981) What controls smooth muscle phenotype? Atherosclerosis 40:347-357