Low doses of ionizing radiation induce nuclear activity in human tumour cell lines which catalyses homologous double-strand recombination

Radiation and Environmental Biophysics

Volumn 36, Issue 1, 1997, Pages 67-70

  Lehnert, Shirley ^a,b   Chow, Terry Y K ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DOUBLE STRANDED DNA;

ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; DNA RECOMBINATION; DNA REPAIR; ENZYME INDUCTION; HUMAN; HUMAN CELL; IONIZING RADIATION; RADIATION EXPOSURE;

ANTINEOPLASTIC AGENTS; CELL NUCLEUS; CELL SURVIVAL; CISPLATIN; COLONIC NEOPLASMS; DNA REPAIR; DNA, NEOPLASM; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; KINETICS; OVARIAN NEOPLASMS; PLASMIDS; RADIATION TOLERANCE; RADIATION, IONIZING; RECOMBINATION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0030888512     PISSN: 0301634X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004110050056     Document Type: Article

References (35)

1. Tartakovsky B, Goldstein O, Krautghamer R, Haran-Ghera N (1993) Low doses of radiation induce systemic production of cytokines: possible contribution to leukemogenesis. Int J Cancer 55: 269-274
2. Witte L, Fuks Z, Haimovitz-Freedman A, Vlodavsky I, Goodman DS, Eldor A (1990) Effects of irradiation on release of growth factor from cultured bovine, porcine and human endothelial cells. Cancer Res 49: 5066-5072
3. Weichselbaum RR, Hallahan DE, Sukhatme V, Dritschilo A, Sherman ML, Kufe DM (1991) Biological consequences of gene regulation after ionizing radiation exposure. J Natl Cancer Inst 83: 480-484
4. Wood RD, Coverley D (1991) DNA excision repair in mammalian cell extracts. Bioessays 13: 447-453
5. Lopez BS, Corteggiani E, Bertrand Mercat E, Coppey J (1992) Directional recombination is initiated at double strand breaks in human nuclear extracts. Nucleic Acids Res 20: 501-506
6. Kucherpalati RS, Spencer J, Moore PD (1985) Homologous recombination catalysed by human cell extracts. Mol Cell Biol 5: 714-720
7. Moore P, Song KY, Chekuri L, Wallace L, Kucherlapati RS (1986) Homologous recombination in a Chinese hamster x-ray sensitive mutant. Mutat Res 160: 149-155
8. Raleigh EA, Lech K, Brent R (1989) Unit 1.4. In: Asubel FM, et al (eds) Current protocols in molecular biology. Publishing Associates and Wiley Interscience, New York
9. Sherman ML, Datta R, Hallahan DE, Weichselbaum RR, Kufe D (1990) Ionizing radiation regulates expression of the c-jun protooncogene Proc Natl Acad Sci USA 87: 5663-5666
10. Woloschak G, Chang-Liu C-M, Jones PS, Jones CA (1990) Modulation of gene expression in Syrian hamster embryo cells following ionizing radiation. Cancer Res 50: 339-344
11. 2 block induced by ionizing radiation. Cancer Res 51: 5113-5117
12. Meyers M, Schea R, Seabury H, Petrowski A, McLaughlin WP, Lee I, Boothman DA (1992) In: Sugahara T, Sagan LA, Aoyama T (eds) Low dose irradiation and biological defence mechanisms. Elsevier, Amsterdam, pp 263-266
13. Lambert M, Borek C (1988) X-ray-induced changes in gene expression in normal and oncogene transformed rat cell lines. J Natl Cancer Inst 80: 1492-1497
14. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig R (1991) Participation of p53 protein in the cellular response to DNA damage. Cancer Res 51: 6304-6311
15. Martin M, Crechet F, Ramounet B, Lefaix J-L (1995) Activation of c-fos by low dose radiation: a mechanism of the adaptive response in skin cells? In: Gene induction and adaptive response in irradiated cells: mechanisms and clinical implications. Radiat Res 141: 118-119
16. Meyers M, McCaffrey J, Odegaard E, Boothman DA (1995) X-ray-inducible transcripts and altered cell cycle regulation are involved in adaptive survival responses in human cells. In: Gene induction and adaptive response in irradiated cells: mechanisms and clinical implications. Radiat Res 141: 119-120
17. Woloschak GE, Chang-Lui C-M (1990) Differential modulation of specific gene expression following high- and low-LET radiations. Radiat Res 124: 183-187
18. Marples B, Joiner MC (1993) The response of Chinese hamster V79 cells to low radiation doses: evidence of enhanced sensitivity of the whole cell population. Radiat Res 133: 41-51
19. Lambin P, Marples B, Fertil B, Malaise EP, Joiner MC (1993) Hypersensitivity of a human tumour cell line to very low dose irradiation. Int J Radiat Biol 63: 639-650
20. Wouters G, Skarsgaard LD (1994) The response of a human tumour cell line to low radiation doses: evidence of enhanced sensitivity. Radiat Res 138: S176-S180
21. Olivieri G, Bodycote J, Wolff S (1984) Adaptive response of human lymphocytes to low concentrations of radioactive thymidine. Science 223: 594-597
22. Shadley D, Wolff S (1987) Very low doses of x-rays can cause human lymphocytes to become less susceptible to ionizing radiation. Mutagenesis 2: 95-96
23. Wolff S, Afzal V, Wienke JK, Olivieri G, Michaeli A (1988) Human lymphocytes exposed to low doses of ionizing radiations become refractory to high doses of radiations as well as to chemical mutagens that induce double-strand breaks in DNA. Int J Radiat Biol 53: 39-48
24. Contopoulou R, Cook VE, Mortimer RK (1987) Analysis of double-strand breakage and repair using orthogonal field alternation gel electrophoresis. Yeast 3: 71-76
25. Haynes RH, Kuntz BA (1981) In: Strathearn JN, Jones EW, Broach JM (eds) The molecular biology of the yeast Saccharomyces cerevisiae: life cycle and inheritance. Cold Spring Harbor Lab Press, Plainview, NY, pp. 371-414
26. Emery HS, Schild D, Kellogg DE, Mortimer RK (1991) Sequence of RAD54, a Saccharomyces cerevisiae gene involved in recombination and repair. Gene 104: 103-106
27. Resnick MA (1976) Repair of double strand breaks in DNA: a model involving recombination. J Theoret Biol 59: 99-106
28. Hendrickson EA, Qin XE, Bump A, Schatz DG, Oettinger M, Weaver DT (1991) A link between double-strand break-related repair and V(D)J recombination: the scid mutation. Proc Natl Acad Sci USA 88: 4061-4065
29. Pergola FM, Zdzienicka MZ, Lieber MR (1993) V(D)J recombination in mammalian cell mutants defective in DNA double strand break repair. Mol Cell Biol 13: 3464-3471
30. Taccioli GE, Rathbun G, Oltz T, Stamato T, Jeggo PA, Alt FW (1993) Impairment of V(D)J recombination in double-strand break repair mutants. Science 260: 207-210
31. Lee SE, Pulaski CR, He DM, Benjamin DM, Voss MJ, Um J, Hendrickson EA (1995) Isolation of mammalian cell mutants that are x-ray sensitive, impaired in DNA double-strand break repair and defective for V(D)J rejoining. Mutat Res 336: 279-291
32. Amundson SA, Chen DJ, Story MD (1995) In: Hagen U, Jung H, Streffer C (eds) Proc. 10th International Congress of Radiation Research, Würzburg, Germany, p 204
33. Jeggo PA (1990) Studies on mammalian mutants deficient in rejoining double-strand breaks DNA. Mutat Res 239: 1-16
34. Danska JS, Pflumio F, Williams CJ, Huner O, Dick JE, Guidos CJ (1994) Rescue of T cell-specific V(D)J recombination in SCID mice by DNA damaging agents. Science 266: 450-455
35. Zhou H, Skov K (1992) Adaptive response of mutagenesis and DNA double-strand break repair in mouse cells induced by low doses of gamma rays In: Sugahara T, et al (eds) Low dose irradiation and biological defense mechanisms. Elsevier, Amsterdam, p 271