Synthesis and DNA binding properties of bis-9-acridinyl derivatives containing mono-, di- and tetra-viologen units as a connector of bis-intercalators

Journal of Heterocyclic Chemistry

Volumn 34, Issue 1, 1997, Pages 123-127

  Takenaka, Shigeori ^a   Sato, Hirotaka ^a   Ihara, Toshihiro ^a   Takagi, Makoto ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACRIDINE DERIVATIVE;

ARTICLE; DNA BINDING; DRUG SYNTHESIS; IN VITRO STUDY; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

EID: 0030888495     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570340120     Document Type: Article

References (14)

1. W. D. Wilson and R. L. Jones, Intercalator Chemistry, M. S. Whittingham and A. J. Jacobson, eds, Academic Press, New York, 1932, p 445.
2. W. D. Wilson, Nucleic Acids in Chemistry and Biology, G. M. Blackburn and M. J. Gait, eds, IRL Press, New York, 1990, p 296.
3. L. P. G. Wakelin, Med. Res. Rev., 6, 275 (1986).
4. J. Barbet, B. P. Roques, S. Combrisson and J.-B. LePecq, Biochemistry, 15, 2642 (1976).
5. N. Capelle, J. Barbet, P. Dessen, S. Blanquet, B. P. Roques and J.-B. LePecq, Biochemisry 18, 3354 (1979).
6. M. Cory, D. D. McKee, J. Kagan, D. W. Henry and J. A. Miller, J. Am. Chem. Soc., 107, 2528 (1985).
7. G. D. Jaycox, G. W. Gribble and M. P. Hacker, J. Hetercoyclic Chem., 24, 1405, (1987).
8. S. Takenaka, T. Ihara and M. Takagi, J. Chem. Soc., Chem. Commun., 1485 (1990).
9. S. Takenaka, T. Ihara and M. Takagi, J. Chem. Letters, 1 (1992).
10. J. D. McGhee and P. H. von Hippel, J. Mol. Biol., 86, 469 (1974)
11. B. F. Cain, B. C. Baguley and W. A. Denny, J. Med. Chem., 21, 658, (1978).
12. D. Wilson, Y. H. Wang, C. R. Krishnamoorthy and J. C. Smith, Biochemistry, 24, 3991 (1985).
13. W. D. Wilson, C. R. Krishnamoorthy, Y.-H. Wang and J. C. Smith, Biopolymers., 24, 1941 (1985).
14. D. J. Dupre and F. A. Robinson, J. Chem. Soc., 549 (1945).