A tandem array of Sp-1 sites and a reverse initiator element are both required for synergistic transcriptional activation of the T-cell-specific MAL gene

DNA and Cell Biology

Volumn 16, Issue 3, 1997, Pages 245-255

  Tugores, Antonio ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR FACTOR; PROTEOLIPID PROTEIN; RNA POLYMERASE II; TRANSCRIPTION FACTOR SP1;

ARTICLE; CELL DIFFERENTIATION; CONSENSUS SEQUENCE; DNA BINDING; DNA FLANKING REGION; GENE ACTIVATION; GENE STRUCTURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DNA INTERACTION; T LYMPHOCYTE; TATA BOX; TRANSACTIVATION; TRANSCRIPTION INITIATION;

EID: 0030888486     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.1997.16.245     Document Type: Article

References (4)

1. ALONSO, M.A., and WEISSMAN, S.M. (1987). cDNA cloning and sequence of MAL, a hydrophobic protein associated with human T-cell differentiation. Proc. Natl. Acad. Sci. USA 84, 1997-2001.
2. ALONSO, M.A., BARTON, D.E., and FRANCKE, U. (1988). Assignment of the T-cell differentiation gene MAL to human chromosome 2, region cen-q13. Immunogenetics 27, 91-95.
3. ANDERSON, G.M., and FREYTAG, S.O. (1991). Synergistic activation of a human promoter in vivo by transcription factor Sp1. Mol. Cell. Biol. 11, 1935-1943.
4. BEATO, M. (1989). Gene regulation by steroid hormones. Cell 56, 335-344.