Low mitochondrial glycerophosphate dehydrogenase activity in lymphocytes of women with gestational diabetes

Hormone and Metabolic Research

Volumn 29, Issue 2, 1997, Pages 60-62

  Vidal, J ^a   Corominola, H ^a   Cardona, F ^a   Levy, I ^a   Cararach, V ^a   Gomis, R ^a   Malaisse, W J ^b  

^a HOSPITAL CLÍNIC   (Spain)

^b FREE UNIVERSITY OF BRUSSELS   (Belgium)

Author keywords

gestational diabetes mellitus; mitochondrial glycerophosphate dehydrogenase

Indexed keywords

GLUTAMATE DEHYDROGENASE; GLYCEROL 3 PHOSPHATE DEHYDROGENASE;

ADULT; ARTICLE; CONTROLLED STUDY; CYTOCHEMISTRY; ENZYME ACTIVITY; FEMALE; HUMAN; LYMPHOCYTE; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL;

EID: 0030888454     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-978986     Document Type: Article

References (12)

1. Coustan DR: Diagnosis of gestational diabetes. Diabetes 40 (Suppl 2): 14-17 (1991).
2. Fernandez-Alvarez J, Conget I, Rasschaert J, Sener A, Gomis R, Malaisse WJ: Enzymatic, metabolic and secretory patterns in human islets of type 2 (non-insulin-dependent) diabetic patients. Diabetologia 37: 177-181 (1994).
3. Leclercq-Meyer V, Malaisse-Lagae F, Coulic V, Akkan AG, Marchand J, Malaisse WJ: Preservation of the anomeric specificity of glucose-induced insulin release in partially pancreatectomized rats. Diabetologia 35: 505-509 (1992).
4. Malaisse WJ: Is type 2 diabetes due to a deficiency of FAD-linked glycerophosphate dehydrogenase in pancreatic islets? Acta Diabetol 30: 1-5 (1993).
5. Malaisse WJ: Pancreatic B-cell FAD-glycerophosphate dehydrogenase deficiency in non-insulin-dependent diabetes: an updated review. In: Insulin Secretion and pancreatic B-Cell Research. Flatt PR and Lenzen S (eds). Smith-Gordon, London (1994), 445-452.
6. Malaisse WJ, Malaisse-Lagae F, Kukel S, Reinhold U, Sener A: Could non-insulin-dependent diabetes mellitus be attributable to a deficiency of FAD-linked glycerophosphate dehydrogenase? Biochem Med Metab Biol 50: 226-232 (1993).
7. Malaisse WJ, Zähner D, Malaisse-Lagae F, Sener A: Absence of FAD-glycerophosphate dehydrogenase deficiency in lymphocytes of insulin-dependent diabetic subjects. Med Sci Res 21: 269-270 (1993).
8. Pendergrass M, Fazioni E, DeFronzo RA: Non-insulin-dependent diabetes mellitus and gestational diabetes mellitus: same disease, another name? Diab Res 3: 566-583 (1995).
9. 2+-dependent activation of FAD-glycerophosphate dehydrogenase. Biochem J 278: 335-340 (1991).
10. Sener A, Malaisse WJ: A sensitive radioisotopic method for the measurement of NAD(P)H: its application to the assay of metabolites and enzymatic activities. Anal Biochem 186: 236-242 (1990).
11. Sener A, Malaisse-Lagae F, Malaisse WJ: Pancreatic islet FAD-linked glycerophosphate dehydrogenase activity in a model of β cell glucotoxicity. Med Sci Res 20: 701-703, 1992.
12. Vidai P, Rasschaert J, Sener A, Gomis R, Malaisse WJ: FAD-glycerophosphate dehydrogenase activity in lymphocytes of type-2 diabetic patients and their relatives. Diab Res Clin Prct 31: 17-25 (1996).