Synthesis of 1,3-diamino-7,8,9,10-tetrahydropyrido[3,2-f]-quinazolines. Inhibitors of Candida albicans dihydrofolate reductase as potential antifungal agents

Journal of Heterocyclic Chemistry

Volumn 34, Issue 1, 1997, Pages 145-151

  Chan, J H ^a   Hong, J S ^a   Kuyper, L F ^a   Jones, M L ^a   Baccanari, D P ^a   Tansik, R L ^a   Boytos, C M ^a   Rudolph, S K ^a   Brown, A D ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 DIAMINO 7 BENZYL 7,8,9,10 TETRAHYDROPYRIDO[3,2 F]QUINAZOLINE; 1,3 DIAMINO 7,8,9,10 TETRAHYDROPYRIDO[3,2 F]QUINAZOLINE DERIVATIVE; ANTIFUNGAL AGENT; DIHYDROFOLATE REDUCTASE; DIHYDROFOLATE REDUCTASE INHIBITOR; FOLINIC ACID; SULFAMETHOXAZOLE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; IN VITRO STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; REACTION ANALYSIS; TUMOR CELL;

EID: 0030888387     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570340123     Document Type: Article

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