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Volumn 34, Issue 1, 1997, Pages 87-91

Synthesis of pyrroloazepines. Facile synthesis of 2-substituted pyrrole derivatives by the phosgene method

Author keywords

[No Author keywords available]

Indexed keywords

6,7 DIHYDRO 7 METHYL 1H,5H PYRROLO[2,3 C]AZEPINE 4,8 DIONE; ALDISIN; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0030888386     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570340115     Document Type: Article
Times cited : (20)

References (16)
  • 3
    • 84970548634 scopus 로고
    • F. J. Schmitz, S. P. Gunasekera, V. Lakshmi and L. M. V. Tillekeratne, J. Nat. Prod., 48, 47 (1985); R. H. Prager and C. Tsopelas, Aust. J. Chem., 43, 367 (1990); idem., ibid., 45, 1771 (1992).
    • (1990) Aust. J. Chem. , vol.43 , pp. 367
    • Prager, R.H.1    Tsopelas, C.2
  • 4
    • 0001448967 scopus 로고
    • F. J. Schmitz, S. P. Gunasekera, V. Lakshmi and L. M. V. Tillekeratne, J. Nat. Prod., 48, 47 (1985); R. H. Prager and C. Tsopelas, Aust. J. Chem., 43, 367 (1990); idem., ibid., 45, 1771 (1992).
    • (1992) Aust. J. Chem. , vol.45 , pp. 1771
    • Prager, R.H.1    Tsopelas, C.2
  • 6
    • 85036440645 scopus 로고
    • A. Mizuno, H. Cho, M. Miya, T. Tatsuoka and T. Ishihara, Japan Patent H2-26137 (1990); Chem. Abstr., 119, P160316m, (1993).
    • (1993) Chem. Abstr. , vol.119
  • 8
    • 1342313703 scopus 로고
    • D. M. Bailey, R. E. Johnson and N. F. Albertson, Org. Synth., 51, 100 (1971); J. W. Harbuck and H. Rapoport, J. Org. Chem., 37, 3618 (1972).
    • (1972) J. Org. Chem. , vol.37 , pp. 3618
    • Harbuck, J.W.1    Rapoport, H.2
  • 10
    • 85036445347 scopus 로고    scopus 로고
    • note
    • Pyrrole-2-carboxylic acid is a useful pharmaceutical building block that is commercially available but is very expensive. Therefore, it cannot be used on a large-scale.
  • 11
    • 85036439769 scopus 로고    scopus 로고
    • note
    • The reverse addition of pyrrole to phosgene solution was also found to give pyrrole-2-carbonyl chloride 5, because chemical conversion to compound 8a occurred with a similar yield.
  • 13
    • 85036443373 scopus 로고
    • K. Schloegl and R. Schloegl, Monatsh. Chem., 95, 922 (1964); Chem. Abstr., 61, 11995f (1964).
    • (1964) Chem. Abstr. , vol.61
  • 14
    • 85036448305 scopus 로고    scopus 로고
    • A commercially available reagent obtained from Hodogaya Chemical Co. Ltd., Tokyo
    • A commercially available reagent obtained from Hodogaya Chemical Co. Ltd., Tokyo.
  • 15
    • 85036439197 scopus 로고    scopus 로고
    • A commercially available reagent obtained from Aldrich Chemical Company, Inc., Milwaukee
    • A commercially available reagent obtained from Aldrich Chemical Company, Inc., Milwaukee.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.