Decreased sensitivity to adriamycin in cadmium-resistant human lung carcinoma A549 cells

Biochemical Pharmacology

Volumn 53, Issue 5, 1997, Pages 747-754

  Hatcher, Emiko L ^a   Alexander, Judith M ^a   Kang, Y James ^a,b  

^a UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

A549 cells; adriamycin; cadmium resistance; cross resistance; glutathione

Indexed keywords

BUTHIONINE SULFOXIMINE; CADMIUM; CATALASE; DOXORUBICIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; METALLOTHIONEIN; SUPEROXIDE DISMUTASE;

ARTICLE; CELL CULTURE; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; CROSS RESISTANCE; DRUG RESISTANCE; DRUG SENSITIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG CARCINOMA; PRIORITY JOURNAL;

ANTIBIOTICS, ANTINEOPLASTIC; BUTHIONINE SULFOXIMINE; CADMIUM; CARCINOGENS, ENVIRONMENTAL; DOXORUBICIN; DRUG RESISTANCE; GLUTATHIONE; HUMANS; LUNG NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0030888036     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(96)00811-8     Document Type: Article

References (36)

1. Volm M, Mattern J and Pommerenke EW, Time course of MDR gene amplification during in vivo selection for doxorubicin-resistance and during reversal in murine leukemia L 1210. Anticancer Res 11: 579-586, 1991.
2. Russo A and Mitchell JB, Potentiation and protection of doxorubicin cytotoxicity by cellular glutathione and modulation. Cancer Treat Rep 69: 1293-1296, 1985.
3. Dusre L, Mimnaugh EG, Myers CE and Sinha BK, Potentiation of doxorubicin cytotoxicity by buthionine sulfoximine in multidrug-resistant human breast tumor cells. Cancer Res 49: 511-515, 1989.
4. Benchekroun MN, Pourquier P, Schott B and Robert J, Doxorubicin-induced lipid peroxidation and glutathione peroxidase activity in tumor cells selected for resistance to doxorubicin. Eur J Biochem 211: 141-146, 1993.
5. Goyer RA, Toxic effects of metals. In: Casarett and Doull's Toxicology: The Basic Science of Poisons (Eds. Amdur MO, Doull J and Klaassen CD), 4th Edn, pp. 634-637. Pergamon Press, New York, 1991.
6. Singhal RK, Anderson ME and Meister A, Glutathione, a first line of defense against cadmium toxicity. FASEB J 1: 220-223, 1987.
7. Kang YJ and Enger MD, Glutathione is involved in the early cadmium cytotoxic response in human lung carcinoma cells. Toxicology 48: 93-101, 1988.
8. Kostic MM, Ognjanovic B, Dimitrijevic S, Zikic RV, Stajn A, Rosic GL and Zivkovic RV, Cadmium-induced changes of antioxidant and metabolic status in red blood cells of rats: In vivo effects. Eur J Haematol 51: 86-92, 1993.
9. Chin K-V, Tanaka S, Darlington G, Pastan I and Gottesman MM, Heat shock and arsenite increase expression of the multidrug resistance (MDR1) gene in human renal carcinoma cells. J Biol Chem 265: 221-226, 1990.
10. Scagliotti GV, Michelotto F, Kalikatzaros G, Leonardo E, Cappia S, Gubetta L, Borasio P and Pozzi E, Detection of multidrug resistance associated P-170 glycoprotein in previously untreated non-small cell lung cancer. Anticancer Res 11: 2207-2210, 1991.
11. Reeve JG, Rabbitts PH and Twentyman RR, Amplification and expression of mdr1 gene in a multidrug resistant variant of small cell lung cancer cell line NCI-H69. Br J Cancer 60: 339-342, 1989.
12. Satoh M, Cherian MG, Imura N and Shimizu H, Modulation of resistance to anticancer drugs by inhibition of metallothionein synthesis. Cancer Res 54: 5255-5257, 1994.
13. Richardson E and Siemann DW, Thiol-related mechanisms of resistance in a murine tumor model. Int J Radiat Oncol Biol Phys 29: 387-392, 1994.
14. Enger MD, Hildebrand CE, Walters RA, Seagrave JC, Barham SS and Hoagland HC, Molecular and somatic cell genetic analysis of metal resistance mechanisms in mammalian cells. In: Molecular and Cellular Approaches to Understanding Mechanisms of Toxicity (Ed. Tasjjian AH), pp. 38-62. President and Fellows of Harvard College, Cambridge, 1984.
15. Hatcher EL, Chen Y and Kang YJ, Cadmium resistance in A549 cells correlates with elevated glutathione content but not antioxidant enzymatic activities. Free Radic Biol Med 19: 805-812, 1995.
16. Tietze F, Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues. Anal Biochem 27: 502-522, 1969.
17. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke MN, Olson BJ and Klenk DC, Measurement of protein using bicinchoninic acid. Anal Biochem 150: 76-85, 1985.
18. Aebi H, Catalase in vitro. Methods Enzymol 105: 121-126, 1984.
19. 2 solutions in the UV). Anal Biochem 49: 474-478, 1972.
20. Flohe L and Gunzler WA, Assays of glutathione peroxidase. Methods Enzymol 105: 114-121, 1984.
21. Carlberg I and Mannervik B, Glutathione reductase. Methods Enzymol 113: 484-490, 1985.
22. Sun Y, Oberley LW and Ying L, A simple method for clinical assay of superoxide dismutase. Clin Chem 34: 497-500, 1988.
23. Babig WH, Pabst MJ and Jakoby WB, Glutathione S-transferases. J Biol Chem 249: 7130-7139, 1974.
24. Church GM and Gilbert W, Genomic sequencing. Proc Natl Acad Sci USA 81: 1991-1995, 1984.
25. Feinberg AP and Vogelstein B, A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132: 6-13, 1983.
26. Kang YJ and Enger MD, Cadmium cytotoxicity correlates with the changes in glutathione content that occur during the logarithmic growth phase of A549-T27 cells. Toxicol Lett 51: 23-28, 1990.
27. Kang YJ and Enger MD, Effect of cellular glutathione depletion on cadmium-induced cytotoxicity in human lung carcinoma cells. Cell Biol Toxicol 3: 347-360, 1987.
28. Manca D, Richard AC, Trottier B and Chevalier G, Studies on lipid peroxidation in rat tissues following administration of low and moderate doses of cadmium chloride. Toxicology 67: 303-323, 1991.
29. Shiraishi N, Uno H and Waalkes MP, Effect of L-ascorbic acid pretreatment on cadmium toxicity in the male Fischer (F344/ NCr) rat. Toxicology 85: 85-100, 1993.
30. Meijer C, Mulder NH, Timmer-Bosscha H, Peters WHM and De Vries EGE, Combined in vitro modulation of adriamycin resistance. Int J Cancer 49: 582-586, 1991.
31. Waxman DJ, Glutathione-S-transferases: Role in alkylating agent resistance and possible target for modulation chemotherapy: A review. Cancer Res 50: 6449-6454, 1990.
32. Webber MM, Rehman SMM and James GT, Metallothionein induction and deinduction in human prostatic carcinoma cells: Relationship with resistance and sensitivity to Adriamycin. Cancer Res 48: 4503-4508, 1988.
33. Lai GM, Moscow JA, Alvarez MG, Fojo AT and Bates SE, Contribution of glutathione and glutathione-dependent enzymes in the reversal of adriamycin resistance in colon carcinoma cell lines. Int J Cancer 49: 688-695, 1991.
34. Lee FYF, Siemann DW and Sutherland RM, Changes in cellular glutathione content during adriamycin treatment in human ovarian cancer - A possible indicator of chemosensitivity. Br J Cancer 60: 291-298, 1989.
35. Edgren M and Revesz L, Compartmentalised depletion of glutathione in cells treated with buthionine sulphoximine. Br J Radiol 60: 723-724, 1987.
36. Jevtovic-Todorovic V and Guenthner TM, Depletion of a discrete nuclear glutathione pool by oxidative stress, but not by buthionine sulfoximine. Biochem Pharmacol 44: 1383-1393, 1992.