Triclabendazole treatment in experimental goat fasciolosis: Anthelmintic efficacy and influence in antibody response and pathophysiology of the disease

Veterinary Parasitology

Volumn 68, Issue 1-2, 1997, Pages 57-67

  Martinez Moreno A ^a   Jimenez V ^a   Martinez Cruz M S ^a   Martinez Moreno F J ^a   Becerra, C ^a   Hernandez S ^a  

^a UNIVERSITY OF CÓRDOBA   (Spain)

Author keywords

Fasciola hepatica; goat; immunology; pathalogy trematoda; triclabendazole

Indexed keywords

TRICLABENDAZOLE;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; FASCIOLA HEPATICA; FASCIOLIASIS; GOAT; NONHUMAN; PATHOPHYSIOLOGY; TRANSDERMAL DRUG ADMINISTRATION;

ANALYSIS OF VARIANCE; ANIMALS; ANTHELMINTICS; ANTIBODIES, HELMINTH; ANTIBODY FORMATION; ASPARTATE AMINOTRANSFERASES; BENZIMIDAZOLES; ENZYME-LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE COUNT; FASCIOLA HEPATICA; FASCIOLIASIS; GAMMA-GLUTAMYLTRANSFERASE; GOAT DISEASES; GOATS; HEMOGLOBINS; L-LACTATE DEHYDROGENASE; LEUKOCYTE COUNT; MALE; SERUM ALBUMIN; TIME FACTORS;

EID: 0030887387     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4017(96)01067-9     Document Type: Article

References (25)

1. Boray, J.C., Crowfoot, P.D., Strong, M.B., Allison, J.R., Schellenbaum, M., Orelli, M.V. and Sarasin, G., 1983. Treatment of immature and mature Fasciola hepatica infections in sheep with triclabendazole. Vet. Rec., 113, 315-317.
2. Bulgin, M.S., Anderson, B.C., Hall, R.F. and Lang, B.Z., 1984. Serum gamma glutamyl transpeptidase activity in cattle with induced fascioliasis. Res. Vet. Sci., 37: 167-171.
3. Chauvin, A., Bouvet, G. and Boulard, C., 1995. Humoral and cellular immune responses to Fasciola hepatica experimental primary and secondary infections in sheep. Int. J. Parasitol., 25: 1227-1241.
4. Dargie, J.D., 1987. The impact on production and mechanisms of pathogenesis of trematode infections in cattle and sheep. Int. J. Parasitol., 17: 453-463.
5. El Haroun, E.M., Elsanhouri, A.A. and Gameel, A.A., 1989. Response of goats to repeated infections with Fasciola gigantica. Vet. Parasitol., 30: 287-296.
6. Ferre, I, Barrio, J.P., Gonzalez-Gallego, J. and Rojo-Vazquez, F.A., 1994. Appetite depresion in sheep experimentally infected with Fasciola hepatica L. Vet. Parasitol., 55: 71-79.
7. Fetterer, R.H., Rew, R.S., Gasbarre, L.C. and Ostlind, D.A., 1985. Prophylactic efficacy of clorsulon agaisnt Fasciola hepatica in calves and sheep. Vet. Parasitol., 18: 21-27.
8. Foyret, W.J., 1988. Eficacy and safety of albendazole against experimentally induced Fasciola hepatica infections in goats. Vet. Parasitol., 26: 261-264.
9. Fuhui, S., Bangfa, L., Chenhui, Q., Ming, L., Mingbao, F., Jiliang, M., Wei, S., Siwen, S. and Xueliang, J., 1989. The efficacy of triclabendazole (Fasinex) against immature and adult Fasciola hepatica in experimentally infected cattle. Vet. Parasitol., 33: 117-124.
10. Hanna, R.E.B., Hughes, D.L. and Taylor, S.M., 1982. Fasciola hepatica: antibody levels in sheep serum before and after treatment with antihelmintic. Res. Vet. Sci., 33: 328-332.
11. Hawkins, C.D., 1984. The use of haemoglobin, packed-cell volume and serum sorbitol dehydrogenase as indicators of the development of fascioliasis in sheep. Vet. Parasitol., 15: 125-133.
12. Jemli, M.H., Braun, J.P., Dorchies, P., Romdhane, M.N. and Kilani, M., 1993. Exploration biochimique et hematologique chez l'agneau infeste experimentalement par Fasciola hepatica. Rec. Med. Vet., 169: 241-249.
13. Keegan, P.S. and Trudgett, A., 1992. Fasciola hepatica in the rat: immune responses associated with the development of resistance to infection. Parasite Immunol., 14: 657-669.
14. Kinabo, L.D.B. and Bogan, J.A., 1988. Pharmacokinetics and efficacy of triclabendazole in goats with induced fascioliasis. J. Vet. Pharmacol. Ther., 11: 254-259.
15. Leathers, C.W., Foyret, W.J., Fetcher, A. and Foyret, K.M., 1982. Clinical fasciolosis in domestic goats in Montana. J. Am. Vet. Med. Assoc., 180: 1451-1454.
16. Martínez A., Martínez-Cruz, M.S., Martínez, F.J., Gutierrez, P.N. and Hernândez, S., 1996. Detection of antibodies to Fasciola hepatica excretory-secretory antigens in experimentally infected goats by enzyme immunosorbent assay. Vet. Parasitol., 62: 247-252.
17. Poitou, I., Baeza, E. and Boulard, C., 1992. Humoral and cellular immune responses in rats during a primary infestation with Fasciola hepatica. Vet. Parasitol., 45: 59-71.
18. Rapic, D., Dzakula, N., Sakar, D. and Richards, R.J., 1988. Comparative efficacy of triclabendazole, nitroxynil and rafoxanide against immature and mature Fasciola hepatica in naturally infected cattle. Vet. Rec., 122: 59-62.
19. Richards R.J., Bowens, F.L., Essenwein, F., Steiger, R.F. and Büscher, G., 1990. The efficacy of triclabendazole and other anthelmintics against Fasciola hepatica in controlled studies in cattle. Vet. Rec., 126: 213-216.
20. Rowland, D.T. and Clampitt, R.B., 1979. Plasma enzyme levels in ruminats infected with Fasciola hepatica. Vet. Parasitol., 5: 155-175.
21. Symonds, H.V., Mather, D.L., Mallinson, C.B. and Hughes, D.L., 1983. Bile flow, bile salt secretion and the excretion of iron, cooper, zinc and manganese in the bile of calves infected with Fasciola hepatica. Res. Vet. Sci., 35: 69-74.
22. Turner, K., Armour, J. and Richards, R.J., 1984. Anthelmintic efficacy of triclabendazole against Fasciola hepatica in sheep. Vet. Rec., 114: 41-42.
23. Wang, P.Y., Jin, J.S., Cai, X.P., Duan, Z.Q. and Yuan, W.Z., 1987. A regional trail of the ELISA for diagnosis fasciolosis in sheeps and goats. Chin. J. Vet. Sci. Technol., 8: 3-7.
24. Wolff, K., Eckert, J., Schneiter, G. and Lutz, H., 1984. Efficacy of triclabendazole against Fasciola hepatica in sheep and goats.
25. Wood, I.B., Amaral, N.K., Bairden K., Duncan, J.L., Kassi, T., Malone, J.B., Pankavich, J.A., Reincke, R.K., Slocombe, O., Taylor, S.M. and Vercruysse, J., 1995. World Association for the Advancement of Veterinary Parasitology (WAAVP) second edition of guidelines for evaluating the efficacy of anthelmintics in ruminants (bovine, ovine, caprine). Vet. Parasitol., 58: 181-213.