Inter- and intraspecies polymorphisms in the cholecystokinin-B/ gastrin receptor alter drug efficacy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 20, 1997, Pages 11043-11048

  Kopin, Alan S ^a   McBride, Edward W ^a   Gordon, Michelle C ^a   Quinn, Suzanne M ^a   Beinborn, Martin ^a  

^a Tupper Research Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [5 (3 AZABICYCLO[3.2.2]NON 3 YL) 2,3 DIHYDRO 1 METHYL 2 OXO 1H 1,4 BENZODIAZEPIN 3 YL] 3 (3 METHYLPHENYL)UREA; CHOLECYSTOKININ B RECEPTOR; GASTRIN RECEPTOR; PD 135158;

ANIMAL CELL; ARTICLE; DRUG EFFECT; DRUG EFFICACY; DRUG RECEPTOR BINDING; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE;

ANIMALS; BENZODIAZEPINONES; COS CELLS; DOGS; ENZYME ACTIVATION; HUMANS; INDOLES; MEGLUMINE; MICE; PHENYLUREA COMPOUNDS; PHOSPHOLIPASE C; POLYMORPHISM, GENETIC; RADIOLIGAND ASSAY; RECEPTORS, CHOLECYSTOKININ; RECOMBINANT PROTEINS; SPECIES SPECIFICITY;

ANIMALIA;

EID: 0030886725     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.20.11043     Document Type: Article

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