α-Adrenoceptor-mediated prejunctional effects of chloroethylclonidine in the canine saphenous vein

Journal of Pharmacology and Experimental Therapeutics

Volumn 282, Issue 3, 1997, Pages 1326-1330

  Guimarães, Serafim ^a   Paiva, Maria Q ^a   Pereira, Oduvaldo ^a,b  

^a Inst of Pharmacol and Therapeutics   (Portugal)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; BRIMONIDINE; CHLOROETHYLCLONIDINE; TRITIUM; YOHIMBINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; DRUG EFFECT; DRUG MECHANISM; ELECTROSTIMULATION THERAPY; EVOKED RESPONSE; FEMALE; MALE; NEUROTRANSMISSION; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; SAPHENOUS VEIN;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; AUTORECEPTORS; CLONIDINE; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MALE; PRAZOSIN; QUINOXALINES; RECEPTORS, ADRENERGIC, ALPHA-2; SAPHENOUS VEIN; YOHIMBINE;

EID: 0030886329     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. AHLQUIST, R. P.: A study of the adrenotropic receptors. Am. J. Physiol. 153: 586-600, 1948.
2. 2-Adrenoceptors blocking profile of SK&F 104078: further evidence for receptor subtypes. Br. J. Pharmacol. 102: 943-949, 1991.
3. 2-adrenoceptors in rat vas deferens. Br. J. Pharmacol. 108: 336-341, 1993.
4. 2-subtype. Pharmacologist 32: 144, 1990.
5. DALE, H. H.: On some physiological actions of ergot. J. Physiol. (Lond) 34: 163-206, 1906.
6. 1-Adrenoceptor subclassification in vascular smooth muscle. Trends Pharmacol. Sci. 7: 347-349, 1986.
7. 2-adrenoceptor activation increases from the distal to the proximal part of the vein of canine limbs. Br. J. Pharmacol. 101: 387-393, 1990.
8. GUIMARÃES, S. AND PAIVA, M. Q.: Two distinct adrenoceptor-biophases in the vasculature: one for α-and the other for β-agonists. Naunyn-Schmiedeberg's Arch. Pharmacol. 316: 195-199, 1981a.
9. GUIMARÃES, S. AND PAIVA M. Q.: Two different biophases for adrenaline released by electrical stimulation or tyramine from the sympathetic nerve endings of the dog saphenous vein. Naunyn-Schmiedeberg's Arch. Pharmacol. 316: 200-204, 1981b.
10. GUIMARÃES, S. AND PAIVA, M. Q: Two different kinds of prejunctional α-adrenoceptors in the canine saphenous vein. J. Auton. Pharmacol. 14: 19, 1994.
11. GUIMARÃES, S., BRANDÃO, F. AND PAIVA, M. Q.: A study of the adrenoceptor-mediated feedback mechanisms by using adrenaline as a false transmitter. Naunyn-Schmiedeberg's Arch. Pharmacol. 305: 185-188, 1978.
12. 1-adrenoceptors. Naunyn-Schmiedeberg's Arch. Pharmacol. 335: 397-402, 1987.
13. 1-adrenoceptors in rat blood vessels. Eur. J. Pharmacol. 190: 97-104, 1987.
14. LECLERC, G., ROUOT, B., SCHWARTZ, J., VELLY, J. AND WERMUTH, C. G.: Studies on some para-substituted clonidine derivatives that exhibit an α-adrenoceptor stimulant activity. Br. J. Pharmacol. 71: 5-9, 1980.
15. LOW, A. M., BOWDISH, D. M., PRASHAD, T. R. AND GASPAR, V.: Interactions of chloroethylclonidine with rauwolscine-and prazosin-sensitive adrenoceptors in dog saphenous vein. Br. J. Pharmacol. 113: 1263-1268, 1994.
16. 1-adrenergic receptor subtypes distinguished by chloroethylclonidine and WB 4101. Mol. Pharmacol. 33: 509-514, 1988.
17. 2-autoreceptors in the rabbit pulmonary artery and human saphenous vein. Naunyn-Schmiedeberg's Arch. Pharmacol. 352: 483-490, 1995.
18. 2-adrenoceptors on the sympathetic nerve fibres of the human saphenous vein: no evidence for involvement in adrenaline-mediated positive feedback loop regulating noradrenergic neurotransmission. Naunyn-Schmiedeberg's Arch. Pharmacol. 337: 408-414, 1988.
19. NUNES, J. P. AND GUIMARÃES, S.: Chloroethylclonidine is an agonist in the dog saphenous vein. In Abstracts of the 7th International Catecholamine Symposium, Amsterdam 1992, p.237. Amsterdam: Stichting 7th Catecholamine Symposium.
20. 2-adrenoceptors in the dog saphenous vein. Naunyn-Schmiedeberg's Arch Pharmacol. 348: 264-268, 1993.
21. ORIOWO, M. A., HIEBLE, J. P. AND RUFFOLO, R. R.: Evidence for heterogeneity of prejunctional alpha-2 adrenoceptors. Pharmacology 43: 1-130, 1991.
22. VARGAS, H. M., ZHOU, L. AND GORMAN, A. J.: Role of vascular alpha-1 adrenoceptor subtypes in the pressor response to sympathetic nerve stimulation in the pithed rat. J. Pharmacol. Exp. Ther. 271: 748-754, 1994.