Semi-automated radioassay for determination of dihydropyrimidine dehydrogenase (DPD) activity Screening cancer patients for DPD deficiency, a condition associated with 5-fluorouracil toxicity

Journal of Chromatography B: Biomedical Applications

Volumn 696, Issue 2, 1997, Pages 183-191

  Johnson, Martin R ^a   Yan, Jieming ^a   Shao, Lingning ^a   Albin, Nicolas ^a   Diasio, Robert B ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

5 Fluorouracil; Dihydropyrimidine dehydrogenase; Enzymes

Indexed keywords

DIHYDROPYRIMIDINE DEHYDROGENASE; FLUOROURACIL;

ARTICLE; AUTOMATION; CANCER PATIENT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME DEFICIENCY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; RADIOASSAY; SCINTILLATION; SCREENING; TECHNIQUE;

ANTIMETABOLITES, ANTINEOPLASTIC; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIHYDROURACIL DEHYDROGENASE (NADP); FLUOROURACIL; HUMANS; KINETICS; LYMPHOCYTES; OXIDOREDUCTASES; RADIOCHEMISTRY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0030885948     PISSN: 15726495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(97)00253-3     Document Type: Article

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