Antiphospholipid syndrome without antiphospholipid antibodies at the time of the thrombotic event: Transient 'seronegative' antiphospholipid syndrome?

Clinical and Experimental Rheumatology

Volumn 15, Issue 5, 1997, Pages 541-544

  Miret, C ^a   Cervera, R ^a   Reverter, J C ^a   Garcia Carrasco M ^a   Ramos, M ^a   Molla M ^a   Font, J ^a   Ingelmo, M ^a  

^a HOSPITAL CLÍNIC   (Spain)

Author keywords

Anticardiolipin antibody; Antiphospholipid syndrome; Lupus anticoagulant; Systemic lupus erythematosus

Indexed keywords

CARDIOLIPIN ANTIBODY; LUPUS ANTICOAGULANT; PHOSPHOLIPID ANTIBODY;

ADULT; ANTIBODY TITER; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; CASE REPORT; FEMALE; FETUS WASTAGE; HUMAN; MICROTHROMBUS; PRIORITY JOURNAL; SERODIAGNOSIS; SYSTEMIC LUPUS ERYTHEMATOSUS; THROMBOCYTOPENIA;

ADULT; ANTIBODIES, ANTICARDIOLIPIN; ANTIPHOSPHOLIPID SYNDROME; BIOLOGICAL MARKERS; FEMALE; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LUPUS ERYTHEMATOSUS, SYSTEMIC; THROMBOCYTOPENIA; THROMBOSIS;

EID: 0030885477     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. ASHERSON RA, CERVERA R: Antiphospholipid syndrome. J Invest Dermatol 1993; 100: 21S-7S.
2. JOSEPH J, SCOPELITIS E: Seronegative antiphospholipid syndrome associated with plasminogen activator inhibitor. Lupus 1994; 3: 201-3.
3. SABBAGA J, NETO JF, CHADDAD R, CECCONELLO I, DEOLIVEIRA RM: A 'primary' thrombotic syndrome: absence of anti-phospholipid antibodies. Clin Rheumatol 1991; 10: 81-3.
4. BRANDT JT, TRIPLETT DA, ALVING B, SCHARRER S: Criteria for the diagnosis of lupus anticoagulants: an update. Thromb Haemost 1995; 74: 1185-90.
5. GHARAVI AE, HARRIS EN, ASHERSON RA, HUGHES GRV: Anticardiolipin antibodies: isotype distribution and phospholipid specifity. Ann Rheum Dis 1987; 46: 1-6.
6. CERVERA R, FONT J, LOPEZ-SOTO A, et al.: Isotype distribution of anticardiolipin antibodies in systemic lupus erythematosus. Prospective analysis of a series of 100 patients. Ann Rheum Dis 1990; 49: 109-13.
7. 2-glycoprotein I in the antiphospholipid syndrome: prevalence and isotype distribution. Br J Rheumatol 1996; 35: 523-8.
8. FRANCÈS C, PIETTE JC, SAADA V, PAPO T, WECHSLER B, COSIDOW O, GODEAU P: Multiple subungual splinter hemorrhages in the antiphospholipid syndrome: a report of five cases and review of the literature. Lupus 1994; 3: 123-8.
9. MUJIC F, LLOYD M, CUADRADO MJ, KHAMASHTA MA, HUGHES GRV: Prevalence and clinical significance of subungual splinter haemorrhages in patients with the antiphosholipid syndrome. Clin Exp Rheumatol 1995; 13: 327-31.
10. KARMOCHKINE M, CACOUB P, PIETTE JC, GODEAU P, BOFFA MC: Antiphosphatidylethanolamine antibody as the sole antiphospholipid antibody in systemic lupus erythematosus with thrombosis. Clin Exp Rheumatol 1992; 10: 603-5.
11. ROUBEY RA: Immunology of the antiphospholipid antibody syndrome. Arthritis Rheum 1996; 39: 1444-54.
12. PÉREZ-VÁZQUEZ ME, CABIEDES J, CABRAL AR, ALARCÓN-SEGOVIA D: Decrease in serum antiphospholipid antibody levels upon development of nephrotic syndrome in patients with systemic lupus erythematosus: relationship to urinary loss of IgG and other factors. Am J Med 1992; 92: 357-62.
13. SILVEIRA LH, JARA LJ, ESPINOZA LR: Transient disappearance of serum antiphospholipid antibodies can also be due to prednisone therapy. Clin Exp Rheumatol 1996; 14: 217-26.
14. DRENKARD C, SANCHEZ-GUERRERO J, ALARCÓN-SEGOVIA D. Fall in antiphospholipid antibody at time of thromboocclusive episodes in systemic lupus erythematosus. J Rheumatol 1989; 16: 614-7.