Electron microscopic localization of nitric oxide I synthase in the organ of Corti of the guinea pig

European Archives of Oto-Rhino-Laryngology

Volumn 254, Issue 8, 1997, Pages 396-400

  Heinrich, U R ^a   Maurer, J ^a   Gosepath, K ^a   Mann, W ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Electron microscopy; Guinea pig hair cells; Immunocytochemistry; Nitric oxide synthase; Sound transduction

Indexed keywords

NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CELL ULTRASTRUCTURE; COCHLEA; CONTROLLED STUDY; CORTI ORGAN; CYTOPLASM; ELECTRON MICROSCOPY; ENZYME LOCALIZATION; GUINEA PIG; HAIR CELL; IMMUNOREACTIVITY; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; GUINEA PIGS; HAIR CELLS; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MICROSCOPY, ELECTRON; NITRIC OXIDE SYNTHASE; ORGAN OF CORTI; PITCH DISCRIMINATION; REFERENCE VALUES; SIGNAL TRANSDUCTION;

EID: 0030884311     PISSN: 09374477     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01642558     Document Type: Article

References (38)

1. Ashmore JF, Meech RW (1986) Ionic basis of membrane potential in outer hair cells of guinea pig cochlea. Nature 322: 368-371
2. Assad JA, Corey DP (1992) An active motor for adaptation by vertebrate hair cells. J Neurosci 12:3291-3309
3. Dulon D, Zajic G, Schacht J (1990) Increasing intracellular free calcium induces circumferential contractions in isolated cochlear outer hair cells. J Neurosci 10:1388-1397
4. Fessenden JD, Coling DE, Schacht J (1994) Detection and characterization of nitric oxide synthase in the mammalian cochlea. Brain Res 668:9-15
5. Fischmeister R, Harzell HC (1987) Cyclic guanosine 3′5′-monophosphate regulates the calcium current in single cells from the frog ventricle. J Physiol 387:453-472
6. Flock Å, Flock B, Ulfendahl M (1986) Mechanics of movement in outer hair cells and a possible structural basis. Arch Otorhinolaryngol 243:83-90
7. Förstermann U, Schmidt HHHW, Pollock JS, Sheng H, Mitchell JA, Warner TD, Nakane M, Murad F (1991) Isoforms of nitric oxide synthase characterization and purification from different cell types. Biochem Pharmacol 42:1849-1857
8. Förstermann U, Gath I, Schwarz P, Closs EI, Kleinert H (1995) Isoforms of nitric oxide synthase - properties, cellular distribution and expressional control. Biochem Pharmacol 50:1321-1332
9. Gitter AH, Zenner H-P, Frömter E (1986) Membrane potential and ion channels in isolated outer hair cells of the guinea pig. ORL 48:68-75
10. Gitter AH, Frömter E, Zenner H-P (1992) C-type potassium channels in the lateral cell membrane of guinea pig outer hair cells. Hear Res 60:13-19
11. Gosepath K, Gath I, Maurer J, Pollock JS, Amedee R, Förstermann U, Mann W (1997) Characterization of NO synthase isoforms expressed in different structures of the guinea pig cochlea. Brain Res 747:26-33
12. Griffiths G (1993) Fine structure immunocytochemistry. Springer, Berlin Heidelberg, New York
13. Griffith OW, Stuehr DJ (1995) Nitric oxide synthases: properties and catalytic mechanism. Annu Rev Physiol 57:707-736
14. Heinrich U-R, Maurer, J Mann W (1997) Alteration of loosely bound calcium in the organ of Corti of the guinea pig after application of the calcium channel blocker Diltiazem. Eur Arch Otorhinolaryngol (in press)
15. Hudspeth AJ (1989) How the ear's works work. Nature 341: 397-404
16. Hudspeth AJ, Gillespie PG (1994) Pulling springs to tune transduction: adaptation by hair cell. Neuron 12:1-9
17. Ignarro LJ (1989) Endothelium-derived nitric oxide: actions and properties. FASEBJ 3:31-36
18. Jaramillo F, Hudspeth AJ (1993) Displacement-clamp measurements of the forces exerted by gating springs in the hair bundle. Proc Natl Acad Sci USA 90:1330-1334
19. Kemp MC, Kuonen DR, Sutton A, Roberts PJ (1988) Rat brain NADPH-dependent diaphorase. Biochem Pharmacol 37:3063-3070
20. Kimitzuki T, Ohmori H (1993) Dihydrostreptomycin modifies adaptation and blocks mechano-electric transducer in chick cochlear hair cells. Brain Res 624:143-150
21. Lenzi D, Roberts WM (1994) Calcium signalling in hair cells. Multiple roles in a compact cell. Curr Opin Neurobiol 4:496-502
22. Levine W, Giuditta A, England S, Strecker HJ (1960) Brain diaphorases. J Neurochem 6:28-36
23. Maurer J, Mann W, Heinrich U-R (1993) Morphologic damage and changes of intracellular calcium-binding sites after acute noise trauma in the organ of Corti of the guinea pig. ORL 55:7-12
24. Moncada S, Palmer RMJ, Higgs EA (1991) Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 43:109-142
25. 2+ current in guinea pig ventricular cells. J Physiol 443:387-404
26. Pollock JS, Förstermann U, Mitchell JA, Warner TD, Schmidt HH, Nakane M, Murad F (1991) Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured native bovine aortic endothelial cells. Proc Natl Acad Sci USA 88:10480-10484
27. Pollock JS, Nakane M, Buttery LDK, Martinez A, Springall D, Polak JM, Förstermann U, Murad F (1993) Characterization and localization of endothelial nitric oxide synthase using specific monoclonal antibodies. Am J Physiol 265:C1379-C1387
28. Pollock JS, Förstermann U, Tracey WR, Nakane M (1995) Nitric oxide synthase isozymes antibodies. Histochem J 27:738-744
29. Rand MJ, Li CG (1995) Nitric oxide as a neurotransmitter in peripheral nerves: Nature of Transmitter and Mechanism of Transmission. Annu Rev Physiol 57:659-682
30. Reimer L (1995) Energy-filtering transmission electron microscopy. (Springer Series in Optical Sciences, vol 71) Springer, Berlin Heidelberg, New York
31. 2+/calmodulin-regulated nitric oxide synthases. Cell Calcium 13:427-434
32. Schmidt HHHW, Gagne GD, Nakane M, Pollock JS, Miller MF, Murad F (1992) Mapping of neuronal nitric oxide synthase in the rat suggests frequent co-localization with NADPH diaphorase but not with soluble guanylyl cyclase, and novel paraneural functions for nitrinergic signal transduction. J Histochem Cytochem 40:1439-1456
33. Stuehr DJ, Cho HJ, Kwon NS, Weise MF, Nathan CF (1991) Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein. Proc Natl Acad Sci USA 88:7773-7777
34. Van den Abbeele T, Tran Ba Hay P, Teulon J (1994) A calcium-activated nonselective cationic channel in the basolateral membrane of outer hair cells of the guinea pig cochlea. Pflügers Arch 417:56-63
35. Whittle BJR (1995) Nitric oxide in physiology and pathology. Histochem J 27:727-737
36. Yau K-W (1994) Cyclic nucleotide-gated channels: an expanding new family of ion channels. Proc Natl Acad Sci USA 91:3481-3483
37. Zenner H-P (1986) Motile responses in outer hair cells. Hear Res 22:83-90
38. Zenner H-P, Zimmermann U, Schmitt U (1985) Reversible contraction of isolated mammalian cochlear hair cells. Hear Res 18:127-133