Biochemical mechanisms of NCS-chromophore-induced DNA cleavage and inhibition of protein kinase activity

Japanese Journal of Cancer and Chemotherapy

Volumn 24, Issue 4, 1997, Pages 443-453

  Ohtsuki, K ^a   Tanoue, S ^a   Karino, A ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Apoptosis; Base specific cleaveage; DNA cleavage; Enediyne antibiotic; Inhibition of protein kinase; Neocarzinostatin chromophore

Indexed keywords

ANTIBIOTIC C 1027; AUROMOMYCIN; CALICHEAMICIN GAMMA1; DYNEMICIN A; ESPERAMICIN A1; KEDARCIDIN; PROTEIN KINASE; ZINOSTATIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CHROMATOPHORE; CONFERENCE PAPER; DNA CLEAVAGE; DRUG DNA INTERACTION; DRUG MECHANISM; ENZYME INHIBITION;

ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; DNA FRAGMENTATION; ENEDIYNES; HUMANS; PHOSPHORYLATION; PROTEIN KINASES; TUMOR CELLS, CULTURED; ZINOSTATIN;

EID: 0030884201     PISSN: 03850684     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (35)