The importance of growth hormone in the regulation of erythropoiesis, red cell mass, and plasma volume in adults with growth hormone deficiency

Journal of Clinical Endocrinology and Metabolism

Volumn 82, Issue 9, 1997, Pages 2985-2990

  Christ, E R ^a   Cummings, M H ^a   Westwood, N B ^a   Sawyer, B M ^a   Pearson, T C ^a   Sonksen P H ^a   Russell Jones, D L ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; GROWTH HORMONE; HUMAN GROWTH HORMONE; PLACEBO; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ADULT; AGED; ARTICLE; BODY MASS; BODY WATER; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; ERYTHROPOIESIS; EXERCISE; FEMALE; GROWTH HORMONE DEFICIENCY; HEMATOCRIT; HUMAN; HYPOPHYSIS ADENOMA; MALE; PLASMA VOLUME; PRIORITY JOURNAL;

ADULT; AGED; BLOOD VOLUME; BODY COMPOSITION; DOUBLE-BLIND METHOD; ERYTHROCYTE VOLUME; ERYTHROPOIESIS; FEMALE; FERRITINS; FOLIC ACID; HUMAN GROWTH HORMONE; HUMANS; MALE; MIDDLE AGED; PLASMA VOLUME; VITAMIN B 12;

ANIMALIA; TULIP BREAKING VIRUS;

EID: 0030884172     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.82.9.2985     Document Type: Article

References (35)

1. De Boer H, Blok GJ, Van der Veen EA. 1995 Clinical aspects of growth hormone deficiency in adults. Endocr Rev. 16:63-85.
2. Salomon F, Cuneo RC, Hesp RS, Sönksen PH. 1989 The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl J Med. 321:1797-1803.
3. Jorgensen JOL, Pedersen SA, Thuesen L, et al. 1989 Beneficial effects of growth hormone treatment in GH-deficient adults. Lancet. 1:1221-1225.
4. De Boer H, Blok GJ, Voerman HJ, De Vries PMJM, van der Veen EA. 1992 Body composition in adult growth hormone deficient men, assessed by anthropometry and bioimpedance analysis. J Clin Endocrinol Metab. 75:833-837.
5. Binnerts A, Swart GR, Wilson JH, et al. 1992 The effect of growth hormone administration in growth hormone deficient adults on bone, protein, carbohydrate and lipid homeostasis, as well as on body composition. Clin Endocrinol (Oxf). 37:79-87.
6. Kushner RF. 1992 Bioelectrical impedance analysis: a review of principles and applications. J Am Coll Nutr. 11:199-209.
7. Moller J, Jorgensen JOL, Moller N, Hansen KW, Pedersen EB, Christiansen JS. 1991 Expansion of extracellular volume and suppression of atrial natriuretic peptide after growth hormone administration in normal man. J Clin Endocrinol Metab. 72:768-772.
8. Hoffman DM, Crampton L, Sernia C, Nguyen TV, Ho KKY. 1996 Short term growth hormone (GH) treatment of GH-deficient adults increases body sodium and extracellular water, but not blood pressure. J Clin Endocrinol Metab. 81:1123-1128.
9. Bengtsson BA, Brummer RJM, Eden S, Bosaeus I. 1989 Body composition in acromegaly. Clin Endocrinol (Oxf). 30:121-130.
10. Strauch G, Lego A, Bricaire H. 1977 Reversible plasma and red cell volumes increases in acromegaly. Acta Endocrinol (Copenh). 85:465-478.
11. Cuneo RC, Salomon F, Wiles CM, Hesp R, Sönksen PH. 1991 Growth hormone treatment in growth hormone deficient adults. II. Effects on exercise performance. J Appl Physiol. 70:688-694.
12. Golde DW, Bersch N, Li CH. 1977 Growth hormone: species-specific stimulation of erythropoiesis in vitro. Science. 196:1112-1113.
13. Claustres M, Chatelain P, Sultan C. 1987 insulin-like growth factor I stimulates human erythroid colony formation in vitro. J Clin Endocrinol Metab. 65:78-82.
14. Kurtz A, Zapf J, Eckhard K, Clemons G, Froesch R, Bauer C. 1988 Insulin-like growth factor 1 stimulates erythropoiesis in hypophysectomiezed rats. Proc Natl Acad Sci USA. 85:7825-7829.
15. Vihervuori E, Virtanen M, Koistinen H, Koistinen R, Sepällä M, Siimes MA. 1996 Hemoglobin level is linked to growth hormone-dependent proteins in short children. Blood. 87:2075-2081.
16. International Committee for Standardization in Hematology. 1973 Standard techniques for the measurement of red-cell and plasma volume. A report by the international committee for standardization in haematology (ICSH): panel of diagnostic applications of radioisotopes in haematology. Br J Haematol. 25:801-814.
17. Pearson TC, Guthrie DL, Simpson J, et al. 1995 Interpretation of measured red cell mass an plasma volume in adults: expert panel of radionuclides of the international council for standardization in haematology. Br J Haematol. 89:748-756.
18. Lappin TR, Elder GE, Taylor T, McMullin MF, Bridges JM. 1988 Comparison of the mouse spleen cell assay and a radioimmunoassay for the measurement of serum erythropoietin. Br J Haematol. 70:117-120.
19. Teale JD, Marks V. 1990 Inappropriately elevated plasma insulin-like growth factor II in relation to suppressed insulin-like growth factor I in the diagnosis of non-islet cell tumor hypoglycaemia. Clin Endocrinol (Oxf). 33:87-98.
20. Merchav S, Tatarsky I, Hochberg Z. 1988 Enhancement of erythropoiesis in vitro by human growth hormone is mediated by insulin-like growth factor. Br J Haematol. 70:267-271.
21. Amato G, Carella C, Fazio S, et al. 1993 Body composition bone metabolism and heart structure and function in growth hormone (GH)-deficient adults before and after GH replacement therapy at low doses. J Clin Endocrinol Metab. 77:1671-1676.
22. Cuneo RC, Salomon F, Wilmshurst P, et al. 1991 Cardiovascular effects of growth hormone treatment in growth-hormone-deficient adults: stimulation of the renin-aldosteron system. Clin Sci. 81:587-592.
23. Cuneo RC, Wallace JD. 1994 Growth hormone, insulin-like growth factors and sport. Endocrinol Metab. 1:3-13.
24. Vihervuori E, Sipilä I, Siimes MA. 1994 Increases in hemoglobin concentration and iron needs in response to growth hormone treatment. J Pediatr. 125:242-245.
25. Anttila R, Siimes MA. 1996 Development of iron status and response to iron medication in pubertal boys. J Pediatr Gastroenterol Nutr. 22:312-317.
26. Fried W. 1995 Erythropoietin. Annu Rev Nutr. 15:353-377.
27. Eckardt KU, Hartmann W, Vetter U, Pohlandt F, Burghardt R, Kurtz A. 1990 Serum immunoreactive erythropoietin of children in health and disease. Eur J Pediatr. 149:459-464.
28. Pressac M, Morgant G, Farmer MA, Aymard P. 1991 Enzyme immunoassay of serum erythropoietin in healthy children: reference values. Ann Clin Biochem. 28:345-350.
29. Philipps AF, Persson B, Hall K, et al. 1988 The effects of biosynthetic insulin-like growth factor supplementation on somatic growth, maturation and erythropoiesis on the neonatal rat. Pediatr Res. 23:298-305.
30. Muta K, Krantz SB, Bondurant MC, Wickrema A. 1994 Distinct roles of erythropoietin, insulin-like growth factor I, and stem cell factor in the development of erythroid progenitor cells. J Clin Invest. 94:34-43.
31. Moller J, Frandsen E, Fisker S, Jorgensen JOL, Christiansen JS. 1996 Decreased plasma and extracellular volume in growth hormone deficient adults and the acute and prolonged effects of GH administration: a controlled experimental study. Clin Endocrinol (Oxf). 44:533-539.
32. Rosen T, Johannsson G, Hallgren P, Caidahl K, Bosaeus I, Bengtsson BA. 1994 Beneficial effects of 12 months replacement therapy with recombinant human growth hormone to growth hormone deficients adults. Endocrinol Metab. 1:55-66.
33. Johannsson G, Rosen T, Lindstedt G, Bosaeus I, Bengtsson BA. 1996 Effect of 2 years of growth hormone treatment on body composition and cardivascular risk factors in adults with growth hormone deficiency. Endocrinol Metab. 3(Suppl A):3-12.
34. Ganong WF. Auerswald W. 1979 Lehrbuch der medizinischen Physiologie. Heidelberg: Springer-Verlag; 9-12.
35. Lammerant J, Haxhe JJ. 1964 Relationsships between cardiac ouptput, blood volume and body composition in chloralose anesthetized normal dogs. Arch Int Physiol Biochem. 72:585-598.