Specific modulation of estrogen receptor mRNA isoforms in rat pituitary throughout the estrous cycle and in response to steroid hormones

Molecular and Cellular Endocrinology

Volumn 131, Issue 2, 1997, Pages 147-155

  Friend, Keith E ^a,b   Resnick, Eileen M ^a   Ang, Le W ^a,b   Shupnik, Margaret A ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Estrogen receptor; Estrous cycle; mRNA isoforms; RNase protection assays

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; MESSENGER RNA; PROGESTERONE; SEX HORMONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ESTRUS CYCLE; EXON; FEMALE; GENE DELETION; HEART; HORMONAL REGULATION; HYPOPHYSIS; HYPOTHALAMUS; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROESTRUS; RAT; TESTIS; UTERUS;

ANIMALS; ESTROGENS; ESTRUS; FEMALE; HYPOTHALAMUS; LIVER; MALE; MYOCARDIUM; PEPTIDE FRAGMENTS; PITUITARY GLAND; PROGESTERONE; RATS; RECEPTORS, ESTROGEN; RNA SPLICING; RNA, MESSENGER; TESTIS; UTERUS; VARIATION (GENETICS);

EID: 0030883831     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(97)00098-1     Document Type: Article

References (31)

1. Demay, F., Tiffoche, C., Thieulant, M.-L., 1996. Sex-and cell-specific expression of an estrogen receptor isoform in the pituitary gland. Neuroendocrinology 63, 522-529.
2. Evans, R.M., 1988. The steroid and thyroid hormone receptor superfamily. Science 240, 889-895.
3. Feinberg, A.P., Vogelstein, B., 1983. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132, 6-13.
4. Fox, S.R., Harlan, R.E., Shivers, B.D., Plaff, D.W., 1990. Chemical characterization of neuroendocrine targets for progesterone in the female rat brain and pituitary. Neuroendocrinology 51, 276-283.
5. Friend, K.E., Chiou, Y.K., Lopes, M.B.S., Laws, E.R. Jr., Hughes, K.M., Shupnik, M.A., 1994. Estrogen receptor expression in human pituitary: correlation with immunohistochemistry in normal tissue, and immunohistochemistry and morphology in macroadenomas. J. Clin. Endocrinol. Metab. 78, 1497-1504.
6. Friend, K.E., Ang, L.W., Shupnik, M.A., 1995. Estrogen regulates the expression of several different estrogen receptor mRNA isoforms in rat pituitary. Proc. Natl. Acad. Sci. USA 92, 4367-4371.
7. Fuller, P.J., 1991. The steroid receptor superfamily: Mechanisms of diversity. FASEB J. 5, 3092-3097.
8. Fuqua, S.A.W., Fitzgerald, S.D., Chamness, G.C., Tandon, A.K., McDonnell, D.P., Nawaz, Z., O'Malley, B.W., McGuire, W.L., 1991. Variant human breast tumor estrogen receptor with constitutive transcriptional activity. Cancer Res. 51, 105-109.
9. Furlow, J.D., Ahrens, H., Mueller, G., Gorski, J., 1990. Antisera to a synthetic peptide recognize native and denatured rat estrogen receptors. Endocrinology 127, 1028-1032.
10. Garcia, T., Lehrer, S., Bloommer, W.D., Schachter, B., 1988. A variant estrogen receptor mRNA is associated with reduced levels of estrogen-binding in human mammary tumors. Mol. Endocrinol. 3, 687-693.
11. Geffroy-Roisne, S., Duval, J., Thieulant, M.-L., 1992. Multiple forms of affinity-labeled estrogen receptors in rat distinct pituitary cells. Endocrinology 131, 1503-1510.
12. Geffroy-Roisne, S., Madigou, T., Pelletier, J., Thieulant, M.-L., 1993. Size heterogeneity of affinity-labelled estrogen receptor in the rat hypothalamo-pituitary axis. Neuroendocrinology 57, 648-653.
13. Horwitz, K.B., Jackson, T.A., Bain, D.L., Richer, J.K., Takimoto, G.S., Tung, L., 1996. Nuclear receptor coactivators and corepressors. Mol. Endocrinol. 10, 1167-1177.
14. Hu, C., Hyder, S., Needleman, D.S., Baker, V.V., 1996. Expression of estrogen receptor variants in normal and neoplastic human uterus. Mol. Cell. Endocrinol. 118, 173-179.
15. Keaveney, M., Klug, J., Dawson, M.T., Nestor, P.V., Neilan, J.G., Forde, R.C., Gannon, F., 1991. Evidence for a previously unidentified upstream exon in the human oestrogen receptor gene. J. Mol. Endocrinol. 6, 111-115.
16. Keefer, D.A., Stumpf, W.E., Petrusz, P., 1976. Quantitative autoradiographic assessment of 3H-estradiol uptake in immunocytochemically characterized pituitary cells. Cell Tissue Res. 166, 25-35.
17. Koehorst, S.G.A., Cox, J.J., Donker, G.H., Lopes da Silva, S., Burbach, J.P.H., Thijssen, J.H.H., Blankenstein, M.A., 1994. Functional analysis of an alternatively spliced estrogen receptor lacking exon 4 isolated from MCF-7 breast cancer cells and meningioma tissue. Mol. Cell. Endocrinol. 101, 237-245.
18. Koike, S., Sakai, M., Muramatsu, M., 1987. Molecular cloning and characterization of the rat estrogen receptor cDNA. Nucleic Acids Res. 15, 2499-2513.
19. Kuiper, G.J.M., Enmark, E., Pelto-Huikko, M., Nilsson, S., Gustafsson, J.-A., 1996. Cloning of a novel estrogen receptor expressed in rat prostate and ovary. Proc. Natl. Acad. Sci. USA 93, 5925-5930.
20. McGuire, W.L., Chamness, G.C., Fuqua, S.A.W., 1991. Estrogen receptor variants in clinical breast cancer. Mol. Endocrinol. 5, 1571-1577.
21. Montano, M.M., Muller, V., Trobaugh, A., Katzenellenbogen, B.S., 1995. The carboxy-terminal F domain of the human estrogen receptor: role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists. Mol. Endocrinol. 9, 814-825.
22. Onate, S.A. Tsai, S.Y., Tsai, M-J., O'Malley, B.W., 1995. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270, 1354-1357.
23. Sanger, F., Nicklen, S., Coulson, A.R., 1997. DNA sequencing with chainterminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467.
24. Shupnik, M.A., Gordon, M.S., Chin, W.W., 1989. Tissue-specific regulation of rat estrogen receptor mRNAs. Mol. Endocrinol. 3, 660-665.
25. Skipper, J.K., Young, L.J., Bergeron, J.M., Tetzlaff, M.T., Osborn, C.T., Crews, D., 1993. Identification of an isoform of the estrogen receptor messenger RNA lacking exon four and present in the brain. Proc. Natl. Acad. Sci. USA 90, 7172-7175.
26. Sprangers, S.A., Fahrenbach, W.H., Bethea, C.L., 1991. Steroid action on estrogen and progestin receptors in monkey pituitary cell cultures. Endocrinology 128, 1907-1917.
27. Tora, L., White, J., Brou, C., Tasset, D., Webster, N., Scheer, E., Chambon, P., 1989. The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell 59, 477-487.
28. Wang, Y., Miksicek, R.J., 1991. Identification of a dominant negative form of the human estrogen receptor. Mol. Endocrinol. 5, 1707-1715.
29. Webb, P., Lopez, G.N., Uht, R.M., Kushner, P.J., 1995. Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell specific estrogen-like effects of antiestrogens. Mol. Endocrinol. 9, 443-456.
30. Wei, L.L., Hawkins, P., Baker, C., Norris, B., Sheridan, P.L., Quinn, P.G., 1996. An amino-terminal truncated progesterone receptor isoform, PRc, enhances progestin-induced transcriptional activity. Mol. Endocrinol. 10, 1379-1387.
31. Zafar, M., Ezzat, S., Ramyar, L., Pan, N., Smyth, H., Asa, S.L., 1995. Cell specific expression of estrogen receptor in the human pituitary and its adenomas. J. Clin. Endocrinol. Metab. 80, 3621-3627.