Lipoic acid reduces the activities of biotin-dependent carboxylases in rat liver

Journal of Nutrition

Volumn 127, Issue 9, 1997, Pages 1776-1781

  Zempleni, Janos ^a   Trusty, Timothy A ^a   Mock, Donald M ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Biotin; Carboxylases; Lipoic acid; Rats

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; BIOTIN; CARBOXYLASE; METHYLCROTONOYL COENZYME A CARBOXYLASE; PROPIONYL COENZYME A CARBOXYLASE; PYRUVATE CARBOXYLASE; THIOCTIC ACID;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEUROPATHY; DRUG MECHANISM; ENZYME ACTIVITY; INTOXICATION; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER INJURY; NONHUMAN; RAT;

ANIMALIA;

EID: 0030883352     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/127.9.1776     Document Type: Article

References (55)

1. Abacus Concepts (1989) SuperANOVA. Abacus Concepts, Inc., Berkely, CA.
2. Abacus Concepts (1996) StatView Reference. Abacus Concepts Inc., Berkely, CA.
3. Altenkirch, H. & Stoltenburg-Didinger, G. (1990) Effects of lipoic acid in hexacarbon-induced neuropathy. Neurotoxicol. Teratol. 12: 619-622.
4. Bowers-Komro, D. M. & McCormick, D. B. (1985) Biotin uptake by isolated rat liver hepatocytes. In: Biotin (Dakshinamurti, K. & Bhagavan, H. N., eds.), vol. 447, pp. 350-358. New York Academy of Sciences, New York, NY.
5. Bowman, B. B., Selhub, J. & Rosenberg, I. H. (1986) Intestinal absorption of biotin in the rat. J. Nutr. 116: 1266-1271.
6. Chang, H.-C., Seidman, I., Teebor, G. & Lane, M. (1967) Liver acetyl CoA carboxylase and fatty acid synthetase: relative activities in the normal state and hereditary obesity. Biochem. Biophys. Res. Commun. 28: 682-686.
7. Chang, H.-H., Rozo, M. L. & McCormick, D. B. (1975) Lipoate metabolism in Pseudomonas putida LP. Arch. Biochem. Biophys. 169: 244-251.
8. Freytag, S. O. & Utter, M. F. (1983) Regulation of the synthesis and degradation of pyruvate carboxylase in 3T3-L1 cells. J. Biol. Chem. 258: 6307-6312.
9. Furr, H. C., Chang, H.-H. & McCormick, D. B. (1978) Lipoate metabolism in Pseudomonas putida LP: thiolsulfinates of lipoate and bisnorlipoate. Arch. Biochem. Biophys. 185: 576-583.
10. Garrett, R. H. & Grisham, C. M. (1995) Biochemistry. Saunders College Publishing, Fort Worth, TX.
11. Green, N. M. (1963) Avidin 3. The nature of the biotin-binding site. Biochem. J. 89: 599-609.
12. Green, N. M. (1975) Avidin. Adv. Protein Chem. 29: 85-133.
13. Grunert, R. (1960) The effect of DL-α-lipoic acid on heavy-metal intoxication in mice and dogs. Arch. Biochem. Biophys. 86: 190-194.
14. Hale, G., Wallis, N. G. & Perham, R. N. (1992) Interaction of avidin with the lipoyl domains in the pyruvate dehydrogenase multienzyme complex: three-dimensional location and similarity to biotinyl domains in carboxylases. Proc. R. Soc. Lond. B. 249: 247-253.
15. Haramaki, N., Packer, L., Assadnazari, H. & Zimmer, G. (1993) Cardiac recovery during post-ischemic reperfusion is improved by combination of vitamin E with dihydrolipoic acid. Biochem. Biophys. Res. Commun. 196:1637-1649.
16. Jacob, S., Henriksen, E., Schiemann, A., Simon, I., Clancy, D., Tritschler, H., June, W., Augustin, H. & Dietze, G. (1995) Enhancement of glucose disposal in patients with type 2 diabetes by alpha-lipoic acid. Drug Res. 45: 872-874.
17. Jörg, J., Metz, F. & Scharafinski, H. (1988) Zur medikamentösen Behandlung der diabetischen Polyneuropathie mit der Alpha-Liponsäure oder Vitamin B-Präparaten. Nervenarzt 59: 36-44.
18. Kagan, V. E., Shvedova, A., Serbinova, E., Khan, S., Swanson, C., Powell, R. & Packer, L. (1992) Dihydrolipoic acid - a universal antioxidant both in the membrane and in the aqueous phase. Biochem. Pharmacol. 44: 1637-1649.
19. 14C-biotin in the rat. J. Nutr. 102: 1453-1464.
20. Majerus, P. & Kilburn, E. (1969) Acetyl coenzyme A carboxylase. The roles of synthesis and degradation in regulation of enzyme levels in rat liver. J. Biol. Chem. 244: 6254-6262.
21. McCormick, D. B. (1975) Biotin. Nutr. Rev. 33: 97-102.
22. McCormick, D. B. & Wright, L. D. (1971) The metabolism of biotin and analogues. In: Metabolism of Vitamins and Trace Elements (Florkin, M. & Stotz, E. H., eds.), pp. 81-110. Elsevier Publishing Company, Amsterdam, The Netherlands.
23. Mitchel, D. H. (1980) Amanita mushroom poisoning. Annu. Rev. Med. 31: 51-57
24. Muller, L. (1989) Protective effects of DL-α-lipoic acid on cadmium-induced deterioration of rat hepatocytes. Toxicology 58: 175-185.
25. Nakanishi, S. & Numa, S. (1970) Purification of rat liver acetyl coenzyme A carboxylase and immunochemical studies on its synthesis and degradation. Eur. J. Biochem. 16: 161-173.
26. Nilsson, L. & Ronge, E. (1992) Lipoamidase and biotinidase deficiency: evidence that lipoamidase and biotinidase are the same enzyme in human serum. Eur. J. Clin. Chem. Clin. Biochem. 30: 119-126.
27. Packer, L. (1994) Antioxidant properties of lipoic acid and its therapeutic effects in prevention of diabetes complications and cataracts. Ann. N.Y. Acad. Sci. 738: 257-264.
28. Packer, L. & Suzuki, Y. J. (1993) Vitamin E and alpha-lipoate: role in antioxidant recycling and activation of the NF-κB transcription factor. Mol. Aspects Med. 14: 229-239.
29. Peter, G. & Borbe, H. O. (1995) Absorption of [7,8-14C]rac-α-lipoic acid from in situ ligated segments of the gastrointestinal tract of the rat. Drug Res. 45: 293-299.
30. Piering, W. F. & Bratanow, N. (1990) Role of the clinical laboratory in guiding treatment of amanita virosa mushroom poisoning: report of two cases. Clin. Chem. 36: 571-574.
31. Plotzker, R., Jensen, D. M. & Payne, J. A. (1982) Amanita virosa acute hepatic necrosis: treatment with thioctic acid. Am. J. Med. Sci. 283: 79-82.
32. Podda, M., Tritschler, H. J., Ulrich, H. & Packer, L. (1994) α-Lipoic acid supplementation prevents symptoms of vitamin E deficiency. Biochem. Biophys. Res. Commun. 204: 98-104.
33. Prehn, J.H.M., Karkoutly, C., Nuglisch, J., Peruche, B. & Krieglstein, J. (1992) Dihydrolipoate reduces neuronal injury after cerebral ischemia. J. Cereb. Blood Flow Metab. 12: 78-87.
34. Saccani, F. & Neri, C. (1970) Determinazione colorimetrica dell'acido tioctico. Boll. Chim. Farm. 109: 278-280.
35. Said, H. M., Ma, T. Y. & Kamanna, V. S. (1994) Uptake of biotin by human hepatoma cell line, Hep G(2): a carrier-mediated process similar to that of normal liver. J. Cell. Physiol. 161: 483-489.
36. Said, H. M. & Redha, R. (1987) A carrier-mediated system for transport of biotin in rat intestine in vitro. Am. J. Physiol. 252: G52-G55.
37. Shih, J.C.H., Rozo, M. L., Wright, L. D. & McCormick, D. B. (1975) Characterization of the growth of Pseudomonas putida LP on lipoate and its analogues: transport, oxidation, sulphur source, and enzyme induction. J. Gen. Microbiol. 86: 217-227.
38. Shih, J.C.H., Williams, P. B., Wright, L. D. & McCormick, D. B. (1974) Properties of lipoic acid analogs. J. Heterocycl. Chem. 11: 119-123.
39. Shih, J.C.H., Wright, L. D. & McCormick, D. B. (1972) Isolation, identification, and characterization of a lipoate-degrading pseudomonad and of a lipoate catabolite. J. Bacteriol. 112: 1043-1051.
40. Spence, J. T. & McCormick, D. B. (1976) Lipoic acid metabolism in the rat. Arch. Biochem. Biophys. 174: 13-19.
41. Stoyanovsky, D. A., Goldman, R., Darrow, R. M., Organisciak, D. T. & Kagan, V. E. (1995) Endogenous ascorbate regenerates vitamin E in the retina directly and in combination with exogenous dihydrolipoic acid. Curr. Eye Res. 14: 181-189.
42. Suormala, T., Wick, H., Bonjour, J. P. & Baumgartner, E. R. (1985) Rapid differential diagnosis of carboxylase deficiencies and evaluation of biotin-reponsiveness in a single blood sample. Clin. Chim. Acta 145: 151-162.
43. Tsuchiya, M., Thompson, D.-FT., Suzuki, Y. J., Cross, C. E. & Packer, L. (1992) Superoxide formed from cigarette smoke impairs polymorphonuclear leukocyte active oxygen generation activity. Arch. Biochem. Biophys. 299: 30-37.
44. Wang, K.-S., Patel, A. R. & Mock, D. M. (1995) Excretion rates and metabolic profile of radio-isotope labeled biotin in the rat. FASEB J. 9: A155 (abs.).
45. Warren, G. B. & Tipton, K. F. (1974) Pig liver pyruvate carboxylase. Purification, properties and cation specificity. Biochem. J. 139: 297-310.
46. Weinberg, M. D. & Utter, M. F. (1979) Effect of thyroid hormone on the turnover of rat liver pyruvate carboxylase and pyruvate dehydrogenase. J. Biol. Chem. 254: 9492-9499.
47. Weinberg, M. D. & Utter, M. F. (1980) Effect of streptozotocin-induced diabetes mellitus on the turnover of rat liver pyruvate carboxylase and pyruvate dehydrogenase. Biochem. J. 188: 601-608.
48. Weiner, D. & Wolf, B. (1991) Biotin uptake, utilization, and efflux in normal and biotin-deficient rat hepatocytes. Biochem. Med. Metabol. Biol. 46: 344-363.
49. Weyler, W., Sweetman, L., Maggio, D. C. & Nyhan, W. L. (1977) Deficiency of propionyl-CoA carboxylase and methylcrotonyl-CoA carboxylase in a patient with methylcrotonylglycinuria. Clin. Chim. Acta 76: 321-328.
50. Witters, L. A. & Kemp, B. E. (1992) Insulin activation of acetyl-CoA carboxylase accompanied by inhibition of the 5′-AMP-activated protein kinase. J. Biol. Chem. 267: 2864-2867.
51. Witters, L. A., Moriarity, D. & Martin, D. B. (1979) Regulation of hepatic acetyl coenzyme A carboxylase by insulin and glucagon. J. Biol. Chem. 254: 6644-6649.
52. Witters, L. A., Watts, T. D., Daniels, D. L. & Evans, J. L. (1988) Insulin stimulates the dephosphorylation and activation of acetyl-CoA carboxylase. Proc. Natl. Acad. Sci. U.S.A. 85: 5473-5477.
53. Wolf, B. (1995) Disorders of biotin metabolism. In: The Metabolic and Molecular Basis of Inherited Disease (Scriver, C. R., Beaudet, A. L., Sly, W. S. & Valle, D., eds.), vol. 2, pp. 3151-3177. McGraw-Hill, Inc., New York, NY.
54. Wolf, B. & Feldman, G. L. (1982) The biotin-dependent carboxylase deficiencies. Am. J. Hum. Genet. 34: 699-716.
55. Ziegler, D., Hanefeld, M., Ruhnau, K., Meibner, H., Lobisch, M., Schutte, K. & Gries, F. (1995) Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant α-lipoic acid. Diabetologia 38: 1425-1433.