Upright posture and the microvasculature in human diabetic neuropathy: A hypothesis

Diabetes

Volumn 46, Issue SUPPL. 2, 1997, Pages

  Ward, John D ^a,b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BODY POSTURE; CONFERENCE PAPER; DIABETIC ANGIOPATHY; DIABETIC NEUROPATHY; HUMAN; MICROVASCULATURE; NERVE INJURY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RAT;

EID: 0030882891     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.46.2.s94     Document Type: Conference Paper

References (34)

1. Greene DA, De Jesus PV, Winegrad AI: Effects of insulin and dietary myo-inositol on impaired motor nerve conduction velocity in acute streptozotocin diabetes. J Clin Invest 55:1326-1336, 1975
2. Sima AAF, Bouchier M, Christensen H: Axonal atrophy in sensory nerves of the diabetic BB-Wistar rat, a possible early correlate of human diabetic neuropathy. Ann Neurol 13:264-272, 1983
3. +-ATPase in the pathogenesis of diabetic complications. N Engl J Med 316:599-607, 1987
4. Gillon KRW, Hawthorne JM, Tomlinson DR: Myonositol and sorbitol metabolism in relation to peripheral nerve function in experimental diabetes in the rat: the effect of aldose reductase inhibition. Diabetologia 25:365-372, 1983
5. Greene DA, Sima AAF, Stevens MJ, Feldman EL, Killen PD, Henry DN, Thomas T, Dananberg J, Lattimer SA: Aldose reductase inhibitors: an approach to the treatment of diabetic nerve damage. Diabetes Metab Rev 9:189-217, 1993
6. Lewin IG, O'Brien IAD, Morgan MH, Corrall RJM: Clinical and neurophysiological studies with the aldose reductase inhibitor Sorbinil in symptomatic diabetic neuropathy. Diabetologia 26:445-448, 1984
7. Santiago JV, Sonksen PA, Boulton AJM, McCloud A, Beg M, Bochenek W, Graepel GJ, Gonen B: Withdrawal of the aldose reductase inhibitor Tolrestat in patients with diabetic neuropathy: effect on nerve function. J Diabetes Complications 7:170-178, 1993
8. Cameron NE, Cotter MA, Dines K, Love A: Effects of aminoguanidine on peripheral nerve function and polyol pathway metabolites in streptozotocin diabetic rats. Diabetologia 35:946-950, 1992
9. Apfel SC, Arezzo JC, Brownlee M, Federoff H, Kessler JA: Nerve growth factor administration protects against experimental diabetic sensory neuropathy. Brain Res 634:7-12, 1994
10. Fagerberg SE: Diabetic neuropathy: a clinical and histological study on the significance of vascular affections. Acta Med Scand 164 (Suppl. 345):1-97, 1959
11. Timperley WR, Ward JD, Preston FE, Duckworth T, O'Malley BC: Clinical and histological studies in diabetic neuropathy: a reassessment of vascular factors in relation to vascular coagulation. Diabetologia 12:237-243, 1976
12. Newrick PG, Wilson AJ, Jakubowski JJ, Boulton AJM, Ward JD: Sural nerve oxygen tension in diabetes. Br Med J 293:1053-1054, 1986
13. Tesfaye S, Harris N, Jakubowski JJ, Boddy C, Wilson RM, Ward JD: Impaired blood flow and arterio-venous shunting in human diabetic neuropathy: a novel technique of nerve photography and fluorescein angiography. Diabetologia 36:1266-1274, 1993
14. Malik RA, Newrick PG, Sharma AK, Ward JD: Microangiography in human diabetic neuropathy: relationship between capillary abnormalities and the severity of neuropathy. Diabetologia 32:92-102, 1989
15. Malik RA, Tesfaye S, Thompson SD, Veves A, Sharma AK, Boulton AJM, Ward JD: Endoneurial localisation of microvascular damage in human diabetic neuropathy. Diabetologia 36:454-459, 1994
16. Malik RA, Tesfaye S, Newrick PG, Boulton AJM, Ward JD: Sural nerve fibre and microvascular pathology in asymptomatic diabetic patients with early neuropathy. In press
17. Said G, Slama G, Selva J: Progressive centripetal degeneration of axon in small fibre type diabetic polyneuropathy: a clinical and pathological study. Brain 106:791-803, 1983
18. DCCT Research Group: Factors in development of diabetic neuropathy: baseline analysis of neuropathy in feasibility phase of Diabetes Control and Com plications Trial. Diabetologia 37:476-483, 1988
19. Cameron NE, Cotter MA: The relationship of vascular changes to metabolic factors in diabetes mellitus and the role in the development of peripheral nerve complications. Diabetes Metab Rev 10:189-224, 1994
20. Zochodne DW, Ho LT, Gross PM: Acute endoneurial ischaemia induced by epineurial endothelin in the rat sciatic nerve. Am J Physiol 263:H1806-H1810, 1992
21. Corbett JA, Tilton RC, Chang K, Hasan KS, Ido Y, Wang JL, Sweetland MA, Lancaster JR, Williamson JR, McDaniel ML: Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction. Diabetes 41:552-556, 1992
22. Cameron NE, Cotter MA, Dines KC, Maxfield EK, Carey F, Mirlees D: Aldose reductase inhibition, nerve perfusion, oxygenation and function in streptozotocin diabetic rats: dose response consideration and independence from a myonositol mechanism. Diabetologia 37:651-663, 1994
23. Cameron NE, Cotter MA, Maxfield EK: Antioxidant treatment prevents the development of peripheral nerve dysfunction in streptozotocin diabetic rats. Diabetologia 36:299-304, 1993
24. Tesfamariam B, Brown ML, Deykin D, Cohen RA: Elevated glucose promotes generation of endothelium derived vasoconstrictor prostanoids in rabbit aorta. J Clin Invest 85:929-932, 1990
25. Cameron NE, Cotter MA, Dines KC, Robertson X, Cox D: The effects of evening primrose oil on peripheral nerve function and capillerisation in streptozotocin diabetic rats: modulation by the cyclo-oxygenase inhibitor flurbiprofen. Br J Pharmacol 109:972-979, 1993
26. Ford I, Malik RA, Newrick PG, Preston FE, Ward JD, Greeaves M: Relationships between haemostatic factors and capillary morphology in human diabetic neuropathy. Thromb Haemost 68:628-633, 1992
27. Johnson PC, Beggs JL: Pathology of the autonomic nerve innervating the vasa nervorum in diabetic neuropathy Diabetic Med 10 (Suppl. 2):56S-61S, 1993
28. Cronenwett JL, Lindenaur SM: Direct measurement of arteriovenous blood flow after lumbar sympathectomy. Surgery 82:82-89, 1977
29. Fagius J: Microneurographic findings in diabetic polyneuropathy with special reference to sympathetic nerve activity. Diabetologia 23:415-422, 1982
30. Raymon G, Hassan AAK, Tooke J: Blood flow in the skin of the foot related to posture in diabetes mellitus. Br Med J 292:87-90, 1986
31. Stevens MJ, Edmunds ME, Foster AVM, Douglas SLE, Watkins PJ: Paradoxical blood flow responses in the diabetic neuropathy foot: an assessment of the contribution of vascular denervation and microangiopathy. Diabetic Med 9:49-54, 1992
32. Flynn MD, Tooke JE: Diabetic neuropathy and the microcirculation. Diabetic Med 12:298-301, 1995
33. Jap AJ, Shore AC, Gartside IB, Gamble J, Tooke JE: Increased microvascular fluid permeability in young type 1 (insulin dependent) diabetic patients. Diabetologia 36:648-652, 1993
34. Henriksen O: Effect of chronic sympathetic denervation upon local regulation of blood flow in human subcutaneous tissue. Acta Physiol Scan 97:377-384, 1976