Improvement of glucose homeostasis and hepatic insulin resistance in ob/ob mice given oral molybdate

Journal of Endocrinology

Volumn 155, Issue 1, 1997, Pages 55-64

  Reul, B A ^a   Becker, D J ^a   Ongemba, L N ^a   Bailey, C J ^b   Henquin, J C ^a   Brichard, S M ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b ASTON UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOKINASE; GLUCOSE; INSULIN; MOLYBDATE SODIUM; MOLYBDIC ACID; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROTEIN TYROSINE KINASE; PYRUVATE KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE OVEREXPRESSION; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HYPERGLYCEMIA; HYPERINSULINEMIA; INSULIN BINDING; INSULIN RESISTANCE; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; OBESITY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; TRANSLATION REGULATION; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE; ADMINISTRATION, ORAL; ANIMALS; BLOOD GLUCOSE; FEMALE; GENE EXPRESSION; GLUCOKINASE; HOMEOSTASIS; INSULIN; INSULIN RESISTANCE; LEPTIN; LIVER; MALE; MICE; MICE, MUTANT STRAINS; MOLYBDENUM; OBESITY; PROTEINS; PYRUVATE KINASE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030882551     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1550055     Document Type: Article

References (44)

1. Bailey CJ, Flatt PR & Atkins TW 1982 Influence of genetic background and age on the expression of the obese hyperglycaemic syndrome in Aston ob/ob mice. International Journal of Obesity 6 11-21.
2. Becker DJ, Ongemba LN, Brichard V, Henquin JC & Brichard SM 1995 Diet- and diabetes-induced changes of ob gene expression in rat adipose tissue. FEBS Letters 371 324-328.
3. Braithwaite SS, Palazuk B, Colca JR, Edwards CW III & Hofman C 1995 Reduced expression of hexokinase II in insulin-resistant diabetes. Diabetes 44 43-48.
4. Brichard SM & Henquin JC 1995 The role of vanadium in the management of diabetes. Trends in Pharmacological Sciences 16 265-270.
5. Brichard SM, Bailey CJ & Henquin JC 1990 Marked improvement of glucose homeostasis in ob/ob diabetic mice given oral vanadate. Diabetes 39 1326-1332.
6. Brichard SM, Henquin JC & Girard J 1993 Phlorizin treatment of diabetic rats partially reverses the abnormal expression of genes involved in hepatic glucose metabolism. Diabetologia 36 292-298.
7. Chan YL, Gutell R, Noller HF & Wool IG 1984 The nucleotide sequence of a rat 185 ribosomal ribonucleic acid gene and a proposal for the secondary structure of 18S ribosomal ribonucleic acid. Journal of Biological Chemistry 259 224-230.
8. Cohen N, Halbertham M, Shlimovich P, Chang CJ, Shamson H & Rossetti L 1995 Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin dependent diabetes mellitus. Journal of Clinical Investigation 95 2501-2509.
9. Ferber S, Meyerovitch J, Kriauciunas KM & Kahn CR 1994 Vanadate normalizes hyperglycemia and phosphoenolpyruvate carboxykinase mRNA levels in ob/ob mice. Metabolism 43 1346-1354.
10. Fillat C, Rodriguez-Gil JE & Guinovart JJ 1992 Molybdate and tungstate act like vanadate on glucose metabolism in isolated hepatocytes. Biochemical Journal 282 659-663.
11. Fransen L, Muller R, Marmenout A, Tavernier J, Van der Heyden J, Kawashima E, Chollet A, Tizard J, Van Heuverswyn H, Van Vliet A et al. 1985 Molecular cloning of mouse tumour necrosis factor cDNA and its eukaryotic expression. Nucleic Acids Research 13 4417-4429.
12. Goldfine AB, Simonson DC, Folli F, Patti ME & Kahn CR 1995 Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies. Journal of Clinical Endocrinology and Metabolism 80 3311-3320.
13. 2 on glucose transport by isolated rat adipocytes. Biochemical Pharmacology 44 174-177.
14. Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK & Friedman JM 1995 Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269 543-546.
15. Heydrick SJ, Jullien D, Gautier N, Tanti JF, Giorgetti S, Van Obberghen E & Le Marchand-Brustel Y 1993 Defect in skeletal muscle phosphatidylinositol-3-kinase in obese insulin-resistant mice. Journal of Clinical Investigation 91 1358-1366.
16. Hofmann C, Lorenz K, Braithwaite SS, Colca JR, Palazuk BJ, Hotamisligil GS & Spiegelman BM 1994 Altered gene expression for tumor necrosis factor-α and its receptors during drug and dietary modulation of insulin resistance. Endocrinology 134 264-270.
17. Hotamisligil GS & Spiegelman BM 1994 Perspectives in diabetes: tumor necrosis factor α: a key component of the obesity-diabetes link. Diabetes 43 1271-1278.
18. Hue L & van de Werve G 1982 Increased concentration of fructose 2,6-bisphosphate in livers of genetically obese mice. FEBS Letters 145 263-266.
19. Iynedjian PB, Ucla C & Mach B 1987 Molecular cloning of glucokinase cDNA. Developmental and dietary regulation of glucokinase mRNA in rat liver. Journal of Biological Chemistry 262 6032-6038.
20. James DE, Strube M & Mueckler M 1989 Molecular cloning and characterization of an insulin-regulatable glucose transporter. Nature 338 83-87.
21. Kahn BB 1992 Facilitative glucose transporters: regulatory mechanisms and dysregulation in diabetes. Journal of Clinical Investigation 89 1367-1374.
22. Kahn CR, Neville DM & Roth J 1973 Insulin-receptor interaction in the obese-hyperglycemic mouse. Journal of Biological Chemistry 248 244-250.
23. Kreutner W, Springer SC & Sherwood JE 1975 Resistance of gluconeogenic and glycogenic pathways in obese-hyperglycemic mice. American Journal of Physiology 228 663-671.
24. Le Marchand-Brustel Y, Ballotti R & Van Obberghen E 1985 Insulin receptor kinase activity in states with altered insulin action. In Insulin Receptors, part A, ch 10, pp 163-179. New York: Liss.
25. Li J, Elberg G, Libman J, Shanzer A, Gefel D & Shechter Y 1995a Insulin-like effects of tungstate and molybdate: mediation through insulin receptor independent pathways. Endocrine 3 631-637.
26. Li J, Elberg G, Gefel D & Shechter Y 1995b Permolybdate and pertungstate -potent stimulators of insulin effects in rat adipocytes: mechanism of action. Biochemistry 34 6218-6225.
27. Lombardo YB, Hron WT, Sobocinski KA & Menehan LA 1983 A metabolic profile of fed and tasting genetically obese mice at 4-5 months of age. Hormone and Metabolic Research 16 (suppl) 37-42.
28. Lord JM, Atkins TW & Bailey CJ 1983 Effect of metformin on hepatocyte insulin receptor binding in normal, streptozotocin diabetic and genetically obese diabetic (ob/ob) mice. Diabetologia 25 108-113.
29. McNeill JH, Delgatty HLM & Battel LM 1991 Insulin-like effects of sodium selenate in STZ-induced diabetic rats. Diabetes 40 1675-1678.
30. Meyerovitch J, Rothenberg P, Shechter Y, Bonner-Weir S & Kahn CR 1991 Vanadate normalizes hyperglycemia in two mouse models of non-insulin-dependent diabetes mellitus. Journal of Clinical Investigation 87 1286-1294.
31. Mooney RA & Bordwell KL 1992 Differential dephosphorylation of the insulin receptor and its 160-kDa substrate (pp160) in rat adipocytes. Journal of Biological Chemistry 267 14054-14060.
32. Noguchi T, Matsuda T, Tomari Y, Yamada K, Imai E, Wang Z, Ikeda H & Tanaka T 1993 The regulation of gene expression by insulin is differentially impaired in the liver of the genetically obese-hyperglycemic Wistar fatty rat. FEBS Letters 328 145-148.
33. Ozcelikay AT, Becker DJ, Ongemba LN, Pettier AM, Henquin JC & Brichard SM 1996 Improvement of glucose and lipid metabolism in diabetic rats treated with molybdate. American Journal of Physiology 270 E344-E352.
34. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T & Collins F 1995 Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269 540-543.
35. Randle PJ, Garland PB, Hales CN & Newsholme EA 1963 The glucose-fatty acid cycle: its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet i 785-789.
36. Rossetti L, Giaccari A, Klein-Robbenhaar E & Vogel LR 1990 The insulin-like properties of trace elements and characterization of their in vivo mode of action. Diabetes 39 1243-1250.
37. Saltiel AR & Olefsky JM 1996 Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes 45 1661-1669.
38. Schwartz MW, Baskin DG, Bukowski TR, Kuijper JL, Foster D, Lasser G, Prunkard DE, Porte D, Woods SC, Seeley RJ & Weigle DS 1996 Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes 45 531-535.
39. Seidman I, Horland AA & Teebor GW 1967 Hepatic glycolytic and gluconeogenic enzymes of the obese-hyperglycemic mouse. Biochimica et Biophysica Acta 146 600-603.
40. Simon MP, Besmond C, Cottreau D, Weber A, Chaumet-Riffaud P, Dreyfus JC, Sala Trépat J, Marie J & Kahn A 1983 Molecular cloning for rat L-type pyruvate kinase and aldolase B. Journal of Biological Chemistry 258 14576-14584.
41. Slieker LJ, Sloop KW, Surface PL, Kriauciunas A, LaQuier F, Manetta J, Bue-Valleskey J & Stephens TW 1996 Regulation of ob mRNA and protein by glucocorticoids and cAMP. Journal of Biological Chemistry 271 5301-5304.
42. Thorens B, Sarkar HK, Kaback HR & Lodish HF 1988 Cloning and functional expression of a novel glucose transporter present in liver, intestine, kidney and β-pancreatic islet cells. Cell 55 281-290.
43. Yoo-Warren H, Monahan JE, Short J, Short H, Bruzel A, Wynshaw-Boris A, Meisner HM, Samols D & Hanson RW 1983 Isolation and characterization of the gene coding for cytosolic phosphoenolpyruvate carboxykinase (GTP) from the rat. Proceedings of the National Academy of Sciences of the USA 80 3656-3660.
44. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L & Friedman JM 1994 Positional cloning of the mouse obese gene and its human homologue. Nature 372 425-432.