Excitatory mechanisms in retinal ganglion cell death in primary open angle glaucoma (POAG)

Clinical Neuroscience

Volumn 4, Issue 5, 1997, Pages 270-273

  Dreyer, Evan B ^a,b   Grosskreutz, Cynthia L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Excitotoxicity; Glaucoma; Glutamate; Retinal ganglion cells

Indexed keywords

EXCITOTOXIN; GLUTAMIC ACID; MEMANTINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BLINDNESS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; HUMAN; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; INTRAPERITONEAL DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MULTICENTER STUDY; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; OPEN ANGLE GLAUCOMA; OPTIC NERVE DISEASE; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; REVIEW; VITREOUS BODY;

ANIMALS; CELL DEATH; EXCITATORY AMINO ACID ANTAGONISTS; GLAUCOMA, OPEN-ANGLE; GLUTAMIC ACID; HUMANS; MEMANTINE; RETINAL GANGLION CELLS; VITREOUS BODY;

EID: 0030881923     PISSN: 10656766     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (24)

1. Anderson DR (1989): Glaucoma: The damage caused by pressure. XLVI Edward Jackson memorial lecture. Am J Ophthalmol 108:485-495.
2. Azuma N, Kawamura M, Kohsaka S (1989): Morphological and immunohistochemical studies on degenerative changes of the retina and the optic nerve in neonatal rats injected with monosodium-L-glutamate. Nippon Ganka Gakkai Zasshi 93:72-79.
3. Bito LZ, Merritt SQ, DeRousseau CJ (1979): Intraocular pressure of rhesus monkey (Macaca mulatta). I. An initial survey of two free-breeding colonies. Invest Ophthalmol Vis Sci 18:785-793.
4. Caprioli J (1989): Correlation of visual function with optic nerve and nerve fiber layer structure in glaucoma. Surv Ophthalmol 33:319-330.
5. Chen HSV, et al. (1992): Open channel block of N-methyl-D-aspartate (NMDA) responses by memantine: Therapeutic advantage against NMDA receptor-mediated neurotoxicity. J Neurosci 12: 4427-4436.
6. Cockburn DM (1983): Does reduction of intraocular pressure (IOP) prevent visual field loss in glaucoma? Am J Optom Physiol Opt 60:705-711.
7. Dreyer EB, Vorwerk C (1995): The glaucomas. In Smith B, Adelman G (ed): Encyl Neurosci New York: Elsevier.
8. Epstein DL (1986): Glaucoma. Philadelphia: Lea and Febiger.
9. Fechtner RD, Weinreb RN (1994): Mechanisms of optic nerve damage in primary open angle glaucoma. Surv Ophthalmol 39:23-42.
10. Grant WM, Burke JF (1982): Why do some people go blind from glaucoma. Ophthalmology 89:991-998.
11. Hart WJ, et al. (1979): Multivariate analysis of the risk of glaucomatous visual field loss. Arch Ophthalmol 97:1455-1458.
12. Lee PY, et al. (1985): Pharmacological testing in the laser-induced monkey glaucoma model. Curr Eye Res 4:775-781.
13. Lee PY, et al. (1987): Intraocular pressure effects of multiple doses of drugs applied to glaucomatous monkey eyes. Arch Ophthalmol 105:249-252.
14. Lucas DR, Newhouse JP (1957): The toxic effect of sodium L-glutamate on the inner layers of the retina. Am Med Assoc Arch Ophthalmol 58:193-201.
15. O'Brien C, et al. (1991): Intraocular pressure and the rate of visual field loss in chronic open angle glaucoma. Am Jour Ophthal 111:491-500.
16. Quigley HA, Addicks EM (1980a): Chronic experimental glaucoma in primates. I. Production of elevated intraocular pressure by anterior chamber injection of autologous ghost red blood cells. Invest Ophthalmol Vis Sci 19:126-136.
17. Quigley HA, Addicks EM (1980): Chronic experimental glaucoma in primates. II. Effect of extended intraocular pressure elevation on optic nerve head and axonal transport. Invest Ophthalmol Vis Sci 19:137-152.
18. Quigley HA, et al. (1980): The mechanism of optic nerve damage in experimental acute intraocular pressure elevation. Invest Ophthalmol Vis Sci 19:505-517.
19. Sautter J, Sabel BA (1993): Recovery of brightness discrimination in adult rats despite progressive loss of retrogradely labelled retinal ganglion cells after controlled optic nerve crush. Eur J Neurosci 5:680-690.
20. Schneider E, et al. (1984): Effects of oral memantine administration on Parkinson symptoms. Results of a placebo-controlled multicenter study. Dtsch Med Wochenschr 109:987.
21. Sterio D (1984): The unbiased estimation of number and sizes of arbitrary particles using the disector method. J Microsc 134:127-136.
22. Wesemann W, Sturm G, Funfgeld EW (1980): Distribution of metabolism of the potential anti-parkinson drug memantine in the human. J Neural Transm Suppl 16:143-148.
23. West M (1993): New stereological methods for counting neurons. Neurobiol aging 14:275-285.
24. Wilson R, et al. (1982): Risk factors for rate of progression of glaucomatous visual field loss: A computer-based analysis. Arch Ophthalmol 100:737-741.