Pre-clinical evaluation of a novel, pneumatic, ventricular assist device (Medos® HIA-VAD®) under pathophysiological conditions

International Journal of Artificial Organs

Volumn 20, Issue 7, 1997, Pages 389-396

  Waldenberger, F R ^a,d   Meyns, B ^b   Reul, H ^c   Eilers, R ^c   Flameng, W ^b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Cardiac assist device; Global cardiac dysfunction; Mechanical circulatory support; Mechanical unloading; Medos HIA VAD ; Regional cardiac dysfunction

Indexed keywords

FIBER OPTIC SENSORS; HEART; LEFT VENTRICULAR ASSIST DEVICES; RECOVERY;

ASSIST DEVICE; CARDIAC ASSIST; CARDIAC ASSIST DEVICE; GLOBAL CARDIAC DYSFUNCTION; MECHANICAL; MECHANICAL CIRCULATORY SUPPORT; MECHANICAL UNLOADING; MEDOS® HIA- VAD®; REGIONAL CARDIAC DYSFUNCTION; WALL THICKENING;

UNLOADING;

LACTIC ACID;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSISTED CIRCULATION; CONTROLLED STUDY; DEFIBRILLATION; DOG; HEART HEMODYNAMICS; HEART INFARCTION; HEART MUSCLE CONTRACTILE FORCE; NONHUMAN; PATHOPHYSIOLOGY; SHEEP; TECHNICAL AID;

EID: 0030881568     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: 10.1177/039139889702000707     Document Type: Article

References (14)

1. Sukehiro S, Flameng W. Effects of left ventricular assist for cardiogenic shock on cardiac function and organ blood flow distribution. Ann Thorac Surg 1990; 50: 374-83.
2. Rakhorst G, Hensens AG, Verkerke Gj, et all. In-vivo evaluation of the "HIA-VAD": a new German ventricular assist device. Thorac Cardiovasc Surgeon 1994; 42: 136-40.
3. Eilers R, Harbott P, Reul H, Rakhorst G, Rau G. Design improvements of the HIA-VAD based on animal experiments. Artif Organs 1994; 18: 473-8.
4. Knierbein B, Rosarius N, Unger A, Reul H, Rau G. CAD-design, stress analysis and in vitro evaluation of three leaflet blood pump valve. J Biomed Eng 1992; 14: 275-85.
5. Waldenberger FR, Meyns B, Wouters P, De Ruyter E, Pongo E, Flameng W. Mechanical unloading properties of axial flow pumps and their effect on myocardial stunning Int J Artif Organs 1995; 18: 766-71.
6. Heikkilä J, Tabakin BS, Hugenholtz PG. Quantification of function in normal and infarcted regions of the left ventricle. Cardiovasc Res 1972; 6: 516-31.
7. Cooper G IV. Load and length regulation of cardiac energetics. Annu Rev Physiol 1990; 52: 505-22.
8. Laschinger JC, Grossi EA, Cunningham JN, et all. Adjunctive left ventricular unloading during myocardial reperfusion plays a major role in minimizing myocardial infarct size. J Thorac Cardiovasc Surg 1985; 90: 80-5.
9. Okamoto F, Allen BS, Buckberg GD, et all. Studies of controlled reperfusion after ischemia. VIII: Regional blood cardioplegic reperfusion during total vented bypass without thoracotomy: a new concept. J Thorac Cardiovasc Surg 1986; 92. 553-63.
10. Allen BS, Okamoto F Buckberg GD, Leaf J, Bugyi H. Studies of controlled reperfusion after ischemia. XII: Effects of "duration" of reperfusate administration versus reperfusate "dose" on regional functional, biochemical, and histochemical recovery. J Thorac Cardiovasc Surg 1986; 92: 594-604.
11. Allen BS, Okamoto F, Buckberg GD, et all. Studies of controlled reperfusion after ischemia. XV: Immediate functional recovery after six hours of regional ischemia by careful control of conditions of reperfusion and composition of reperfusate. J Thorac Cardiovasc Surg 1986; 92: 621-35.
12. Waldenberger FR, Andres T, Flameng WJ. Effects of unloaded reperfusion on mitochondrial function in the postischemic myocardium. Artificial Organs 1994; 18: 206-13.
13. Gustovitz AL, Sobel BE, Roberts R. Progressive nature of myocardial injury in selected patients with cardiogenic shock Am J Cardiol 1978; 41: 469-75.
14. Taenaka Y, Takano H, Noda H, Kinoshita M. A pediatric ventriculat assist device: Its development and experimental evaluation of hemodynamic effects on postoperative heart failure of congenital heart diseases. Artif Organs 1990; 14: 49-56.