Internalization of fractionated 3H-heparin by the scavenger-like receptor in rat liver parenchymal cells in primary culture

Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents

Volumn 4, Issue 3, 1997, Pages 181-185

  Urano, Kimihiko ^a   Haba, Masami ^a   Yuasa, Hiroaki ^a   Watanabe, Jun ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

Endocytosis; Heparin; Internalization; Parenchymal cells; Scavenger receptor

Indexed keywords

HEPARIN; RECEPTOR; TRITIUM;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HUMAN; IN VITRO STUDY; INTERNALIZATION; ISOTOPE LABELING; LIVER PARENCHYMA; MALE; PRIORITY JOURNAL; RAT;

EID: 0030881351     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.3109/10717549709051890     Document Type: Article

References (16)

1. Bitter, T., and Muir, H. M. 1962. A modified uronic acid reaction. Anal. Biochem. 4:330-334.
2. Dautry-Varsat, A., Ciechanover, A., and Lodish, H. F. 1983. pH and the recycling of transferrin during receptor-mediated endocytosis. Proc. Natl. Acad. Sci. USA 80:2258-2262.
3. DeRijke, Y. B., Biessen, E. A., Vogelezang, C. J., and van Berkel, T. J. 1994. Binding characteristics of scavenger receptors on liver endothelial and Kupffer cells for modified low-density lipoproteins. Biochem. J. 304:69-73.
4. Gibson, A. E., Noel, R. J., Herlithy, J. T., and Ward, W. F. 1989. Phenylarsine oxide inhibition of endocytosis: Effects on asialofetuin internalization. Am. J. Physiol. 257:C182-C184.
5. Krieger, M., Acton, S., Ashkenas, J., Pearson, A., Penman, M., and Resnick, D. 1993. Molecular flypaper, host defense, and atherosclerosis: Structure, binding properties, and functions of macrophage scavenger receptors. J. Biol. Chem. 268:4569-4572.
6. Moscatelli, D. 1987. High and low affinity binding sites for basic fibroblast growth factor on cultured cells: Absence of a role for low affinity binding in the stimulation of plasminogen activator production by bovine capillary endothelial cells. J. Cell. Physiol. 131:123-130.
7. Nishikawa, M., Hirabayashi, H., Takakura, Y., and Hashida, M. 1995. Design for cell-specific targeting of proteins utilizing sugar-recognition mechanism: Effect of molecular weight of proteins on targeting efficiency. Pharm. Res. 12:209-214.
8. Rathinavelu, A., and Isom, G. E. 1991. Differential internalization and processing of atrial-natriuretic-factor B and C receptors in PC12 cells. Biochem. J. 276:493-497.
9. Tokuda, H., Masuda, S., Takakura, Y., Sezaki, H., and Hashida, M. 1993. Specific uptake of succunylated proteins via a scavenger receptor-mediated mechanism in cultured brain microvessel endothelial cells. Biochem. Biophys. Res. Commun. 196:18-24.
10. Verstraete, M. 1990. Pharmacotherapeutic aspects of unfractionated and low molecular weight heparins. Drugs 40:498-530.
11. 3H]heparin in rat parenchymal hepatocytes in primary culture: Effect of transport inhibitors on the uptake. Biol. Pharm. Bull. 16:497-500.
12. 3H]heparin by rat hepatocytes in the primary culture. Biol. Pharm. Bull. 18:443-446.
13. 3H]heparin in isolated rat Kupffer cells: Involvement of scavenger receptors. Biol. Pharm. Bull. 19:581-586.
14. Yamazaki, M., Suzuki, H., Sugiyama, Y., Iga, T., and Hanano, M. 1992. Uptake of organic anions by isolated rat hepatocytes. A classification in terms of ATP-dependency. J. Hepatol. 14:41-47.
15. +-independent multispecific anion transporter mediates active transport of pravastatin into rat liver. Am. J. Physiol. 264:G36-G44.
16. Yanai, S., Sugiyama, Y., Kim, D. C., Iga, T., Fuwa, T., and Hanano, M. 1991. Kinetic analysis of receptor-mediated endocytosis of epidermal growth factor by isolated rat hepatocytes. Am. J. Physiol. 260:C457-C467.