Topographical analysis of the EEG effects of a subconvulsive dose of lidocaine in healthy volunteers

Acta Anaesthesiologica Scandinavica

Volumn 41, Issue 8, 1997, Pages 1039-1046

  Detsch, O ^a,b,c   Erkens, U ^a   Jacofsky, U ^a   Thiel, A ^a   Kochs, E ^b   Hempelmann, G ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Anesthetics; Anti arrhythmia agents; Brain electrical activity mapping; Electroencephalography; Intravenous supply; Lidocaine; Local; Monitoring

Indexed keywords

LIDOCAINE;

ADULT; ANTICONVULSANT THERAPY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CONVULSION; CROSSOVER PROCEDURE; DOSE RESPONSE; DRUG BLOOD LEVEL; ELECTROENCEPHALOGRAM; HEMISPHERIC DOMINANCE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PSYCHOMOTOR ACTIVITY; SCORING SYSTEM; SINGLE BLIND PROCEDURE;

EID: 0030881219     PISSN: 00015172     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-6576.1997.tb04833.x     Document Type: Article

References (28)

1. Collinsworth KA, Kalman SM, Harrison DC. The clinical pharmacology of lidocaine as an antiarrhythmic drug. Circulation 1974: 50: 1217-1230.
2. Davis RF. Etiology and treatment of perioperative cardiac arrhythmias. In: Kaplan JA, ed. Cardiac anesthesia. Philadelphia: W B Saunders, 1993: 170-205.
3. Himes RS, DiFazio CA, Burney RG. Effects of lidocaine on the anesthetic requirements for nitrous oxide and halothane. Anesthesiology 1977: 47: 437-440.
4. Tanelian DL, Brose WG. Neuropathic pain can be relieved by drugs that are use-dependent sodium channel blockers: lidocaine, carbamazepine, and mexiletine. Anesthesiology 1991: 74: 949-951.
5. Marchettini P, Lacerenza M, Marangoni C, Pellegata G, Sotgiu ML, Smirne S. Lidocaine test in neuralgia. Pain 1992: 48: 377-382.
6. Strichartz GR, Berde CB. Local anesthetics. In: Miller RD, ed. Anesthesia. New York: Churchill Livingstone, 1994: 489-521.
7. Garfield JM, Gugino L. Central effects of local anesthetic agents. In: Strichartz GR, ed. Local anesthetics. Berlin: Springer, 1987: 253-284.
8. Scott DB. Evaluation of the toxicity of local anaesthetic agents in man. Br J Anaesth 1975: 47: 56-61.
9. Scott DB. Toxic effects of local anaesthetic agents on the central nervous system. Br J Anaesth 1986: 58: 732-735.
10. Steen PA, Michenfelder JD. Neurotoxicity of anesthetics. Anesthesiology 1979: 50: 437-453.
11. Tucker GT. Pharmacokinetics of local anaesthetics. Br J Anaesth 1986: 58: 717-731.
12. Munson ES, Martucci RW, Wagman IH. Bupivacaine and lignocaine induced seizures in rhesus monkeys. Br J Anaesth 1972: 44: 1025-1029.
13. Sakabe T, Maekawa T, Ishikawa T, Takeshita H. The effects of lidocaine on canine cerebral metabolism and circulation related to the electroencephalogram. Anesthesiology 1974: 40: 433-441.
14. Englesson S, Matousek M. Central nervous system effects of local anaesthetic agents. Br J Anaesth 1975: 47: 241-246.
15. Seo N, Oshima E, Stevens J, Mori K. The tetraphasic action of lidocaine on CNS electrical activity and behavior in cats. Anesthesiology 1982: 57: 451-457.
16. Usubiaga JE, Wikinski J, Ferrero R, Usubiaga LE, Wikinski R. Local anesthetic-induced convulsions in man - An electroencephalographic study. Anesth Analg 1966: 45: 611-620.
17. Adams HA, Biscoping J, Ludolf K, Börgmann A, Bachmann-M B, Hempelmann G. The detection of local anesthetic substances by HPLC/UV. Regional Anaesthesie 1989: 12: 53-57.
18. Roetman KJ, Eisenach JC. Evaluation of lidocaine as an intravenous test dose for epidural anesthesia. Anesthesiology 1988: 69: A669.
19. Strebel S, Frei F, Rosow CE, Drewe J. Central nervous system symptoms after intravenous lignocaine: dose-response during pregnancy. Eur J Anaesthesiol 1993: 10: 101-104.
20. Lehmann D. Principles of spatial analysis. In: Gevins A, Rémond A, eds. Handbook of electroencephalography and clinical neurophysiology. Volume 1: Methods of analysis of brain electrical and magnetic signals. Amsterdam: Elsevier, 1987: 309-354.
21. Schober F, Schellenberg R, Dimpfel W. Reflection of mental exercise in the dynamic quantitative topographical EEG. Neuropsychobiology 1995: 31: 98-112.
22. Bachmann-M B, Biscoping J, Adams HA, Menges T, Krumholz W, Hempelmann G. The importance of the site of blood sampling in determination of plasma concentrations of local anesthetics. Regional Anaesthesie 1990: 13: 16-20.
23. Smith ER, Duce BR. The acute antiarrhythmic and toxic effects in mice and dogs of 2-ethylamino-2′, 6′-acetoxylidine (L-86), a metabolite of lidocaine. J Pharmacol Exp Ther 1971: 179: 580-585.
24. Blumer J, Strong JM, Atkinson AJ. The convulsant potency of lidocaine and its N-dealkylated metabolites. J Pharmacol Exp Ther 1973: 186: 31-36.
25. Wagman IH, De Jong RH, Prince DA. Effects of lidocaine on the central nervous system. Anesthesiology 1967: 28: 155-169.
26. Foldes FF, Molloy R, McNall PG, Koukal LR. Comparison of toxicity of intravenously given local anesthetic agents in man. JAMA 1960: 172: 1493-1498.
27. Eriksson E. Effects of local anaesthetics on the EEG. Acta Anaesthesiol Scand 1966: 10 (Suppl 25): 37-41.
28. Shibata M, Shingu K, Murakawa M, Adachi T, Osawa M, Nakao S, et al. Tetraphasic actions of local anesthetics on central nervous system electrical activities in cats. Reg Anesth 1994: 19: 255-263.