Structure and dynamic studies by NMR of the potent sweet protein monellin and a non-sweet analog. Evidence on the importance of residue Asp(B7) for sweet taste

FEBS Letters

Volumn 413, Issue 3, 1997, Pages 409-416

  Mizukoshi, Toshimi ^a   Kohmura, Masanori ^a   Suzuki, Ei Ichiro ^a   Ariyoshi, Yasuo ^a  

^a AJINOMOTO CO INC   (Japan)

Author keywords

Active residue Asp(B7); Model free analysis; Monellin; Selectively 15N labeled monellin; Solid phase synthesis

Indexed keywords

MONELLIN; NITROGEN 15; SWEET PROTEIN;

ARTICLE; CRYSTAL STRUCTURE; ISOTOPE LABELING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN VARIANT; STRUCTURE ACTIVITY RELATION; SWEETNESS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; AMINOBUTYRIC ACIDS; ASPARTIC ACID; MACROMOLECULAR SUBSTANCES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; PEPTIDES; PLANT PROTEINS; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP; SWEETENING AGENTS;

EID: 0030880669     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)00945-9     Document Type: Article

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