AIDS clinical trials group study 094: A phase I/II trial of ABV chemotherapy with zidovudine and recombinant human GM-CSF in AIDS-related Kaposi's sarcoma

Cancer Journal from Scientific American

Volumn 3, Issue 5, 1997, Pages 278-283

  Gill, Parkash S ^a   Mitsuyasu, Ronald T ^b   Montgomery, Terri ^a   Huang, Jenny ^c   Cabriales, Suzanne ^b   Testa, Marcia ^c   Espina, Byron M ^a   Levine, Alexandra M ^a   Miles, Steven A ^b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

AIDS; Chemotherapy; GM CSF; Kaposi's sarcoma

Indexed keywords

BLEOMYCIN; DOXORUBICIN; ETOPOSIDE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; VINCA ALKALOID; VINCRISTINE; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADVANCED CANCER; AIDS RELATED COMPLEX; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CLINICAL TRIAL; CYTOTOXICITY; DISEASE COURSE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; KAPOSI SARCOMA; NEUTROPENIA; OPPORTUNISTIC INFECTION; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SUBCUTANEOUS DRUG ADMINISTRATION;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BLEOMYCIN; DOXORUBICIN; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; LUNG; MALE; SARCOMA, KAPOSI; TREATMENT OUTCOME; VINCRISTINE; ZIDOVUDINE;

EID: 0030880590     PISSN: 10814442     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Centers for Disease Control and Prevention: HIV/AIDS Surveillance Report. February 1993:1-23.
2. Laubenstein LJ, Kriegel RL, Odajnk CM et al. Treatment of epidemic Kaposi's sarcoma with etoposide or a combination of doxorubicin, bleomycin, and vinblastine. J Clin Oncol 1984;2:1115-1120.
3. Volberding PA, Abrams DI, Conant M et al. Vinblastine therapy for Kaposi's sarcoma in the acquired immunodeficiency syndrome. Ann Intern Med 1985;103:335-338.
4. Mintzer DM, Real FX, Jovino L et al. Treatment of Kaposi's sarcoma and thrombocytopenia with vincristine in patients with the acquired immunodeficiency syndrome. Ann Intern Med 1985; 102:200-202.
5. Gelmann E, Longo D, Lane H et al. Combination chemotherapy of disseminated Kaposi's sarcoma in patients with the acquired immune deficiency syndrome. Am J Med 1987;82:456-462.
6. Gill PS, Rarick MU, Espina BM et al. Advanced AIDS-related Kaposi's sarcoma: results of pilot studies using combination chemotherapy (low dose Adriamycin, bleomycin and vincristine). Cancer 1990;65:1074-1078.
7. Gill PS, Rarick MU, McCutchan JA et al. Systemic treatment of AIDS-related Kaposi's sarcoma: results of a randomized trial. Am J Med 1991;90:427-433.
8. Fischl MA, Krown SE, O'Boyle KP et al. Weekly doxorubicin in the treatment of patients with AIDS-related Kaposi's sarcoma. J Acquir Immune Defic Syndr 1993;6:259-264.
9. Fischl MA, Richman DD, Grieco MJ et al. The efficacy of Azidothymidine (zidovudine) with the treatment of patients with AIDS and AIDS-related complex. N Engl J Med 1987;317:185-191.
10. Groopman J, Mitsuyasu R, DeLeo M et al. Effect of recombinant human granulocyte-macrophage colony-stimulating factor on myelopoiesis in the acquired immunodeficiency syndrome. N Engl J Med 1987;317;593-598.
11. Gill PS, Miles SA, Mitsuyasu RT et al. Phase I AIDS Clinical Trials Group (075) study of Adriamycin, bleomycin, vincristine chemotherapy with zidovudine in the treatment of AIDS-related Kaposi's sarcoma.AIDS 1994;8:1695-1699.
12. Lieschke GJ, Maher D, Cebon J et al. Effects of batterially synthesized recombinant human granulocyte-macrophage colony-stimulating factor and comparison with subcutaneous administration. Ann Intern Med 1989;110:357-364.
13. Antman KS, Griffin JD, Elias A et al. Effect of recombinant granulocyte-macrophage colony-stimulating factor on chemotherapy-induced myelosuppression. N Engl J Med 1988;319:593-581.
14. Gill PS, Bernstein-Singer M, Espina BM et al. Adriamycin, bleomycin, and vincristine chemotherapy with recombinant granulocyte-macrophage colony-stimulating factor in the treatment of AIDS-related Kaposi's sarcoma. AIDS 1992;6:1477-1481.
15. Ireland-Gill A, Espina BM, Akil B et al. Treatment of acquired immunodeficiency syndrome-related Kaposi's sarcoma using bleomycin-containing combination chemotherapy regimens. Semin Oncol 1992;19:32-37.
16. Folks TM, Justement J, Kinter A et al. Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line. Science 1987;238:800-802.
17. Kaplan LD, Kahn JO, Crowe S et al. Clinical and virologie effects of recombinant human granulocyte-macrophage colony-stimulating factor in patients receiving chemotherapy for human immuno-deficiency virus-associated non-Hodgkin's lymphoma: results of a randomized trial. J Clin Oncol 1991;9:929-940.
18. Scadden DT, Bering HA, Levine JD et al. Granulocyte-macrophage colony-stimulating factor mitigates the neutropenia of combined interferon-alpha and zidovudine treatment of acquired immunodeficiency syndrome-associated Kaposi's sarcoma. J Clin Oncol 1991;9:802-808.