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Volumn 26, Issue 3, 1997, Pages 523-537

Metformin

Author keywords

[No Author keywords available]

Indexed keywords

BIGUANIDE; BUFORMIN; CHLORHEXIDINE; CHLORPROPAMIDE; CHOLESTEROL; FATTY ACID; GLUCOSE; GLYCOGEN; GUANIDINE DERIVATIVE; INSULIN; KETONE; LACTIC ACID; LIPID; METFORMIN; ORAL ANTIDIABETIC AGENT; PHENFORMIN; PLASMA PROTEIN; PLASMIN; PLASMINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PYRUVIC ACID; SULFONYLUREA DERIVATIVE; SYNTHALIN B; TOLBUTAMIDE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 0030879891     PISSN: 08898529     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0889-8529(05)70265-6     Document Type: Article
Times cited : (56)

References (98)
  • 1
    • 0014060182 scopus 로고
    • Treatment of the obese diabetic: A comparative study of placebo, sulphonylurea and phenformin
    • E. Abramson R.A. Arky Treatment of the obese diabetic: A comparative study of placebo, sulphonylurea and phenformin Metabolism 16 1967 204
    • (1967) Metabolism , vol.16 , pp. 204
    • Abramson, E.1    Arky, R.A.2
  • 3
    • 0017078655 scopus 로고
    • Fibrinolysis and diabetic retinopathy
    • L.O. Almer M. Pandolfi Fibrinolysis and diabetic retinopathy Diabetes 25 suppl2 1976 807
    • (1976) Diabetes , vol.25 , Issue.suppl2 , pp. 807
    • Almer, L.O.1    Pandolfi, M.2
  • 4
    • 0027287972 scopus 로고
    • Plasminogen activator inhibitor-1 synthesis in the human hepatoma cell line Hep G2: Metformin inhibits the stimulating effect of insulin
    • F. Anfosso N. Chomiki M.C. Alessi Plasminogen activator inhibitor-1 synthesis in the human hepatoma cell line Hep G2: Metformin inhibits the stimulating effect of insulin J Clin Invest 91 1993 2185
    • (1993) J Clin Invest , vol.91 , pp. 2185
    • Anfosso, F.1    Chomiki, N.2    Alessi, M.C.3
  • 5
    • 0023879966 scopus 로고
    • Metformin revisited: Its actions and indications for use
    • C.J. Bailey Metformin revisited: Its actions and indications for use Diabet Med 5 1988 315
    • (1988) Diabet Med , vol.5 , pp. 315
    • Bailey, C.J.1
  • 6
    • 0029168034 scopus 로고
    • Metformin and intestinal glucose handling
    • C.J. Bailey Metformin and intestinal glucose handling Diabetes Metab Rev 11 1995 523
    • (1995) Diabetes Metab Rev , vol.11 , pp. 523
    • Bailey, C.J.1
  • 7
    • 0022531205 scopus 로고
    • Anorectic effect of metformin in lean and genetically obese hyperglycaemic (ob/ob) mice
    • C.J. Bailey P.R. Flatt C. Ewan Anorectic effect of metformin in lean and genetically obese hyperglycaemic (ob/ob) mice Arch Int Pharmacodyn Ther 282 1986 233
    • (1986) Arch Int Pharmacodyn Ther , vol.282 , pp. 233
    • Bailey, C.J.1    Flatt, P.R.2    Ewan, C.3
  • 8
    • 0029894271 scopus 로고    scopus 로고
    • Clinical significance of insulin resistance
    • P.M. Bell Clinical significance of insulin resistance Diabet Med 13 1996 504
    • (1996) Diabet Med , vol.13 , pp. 504
    • Bell, P.M.1
  • 9
    • 0021691098 scopus 로고
    • Relationships between insulin secretion, insulin action and fasting plasma glucose concentration in nondiabetic and noninsulin dependent diabetic subjects
    • C. Bogardus S. Lillioja B.V. Howard Relationships between insulin secretion, insulin action and fasting plasma glucose concentration in nondiabetic and noninsulin dependent diabetic subjects J Clin Invest 74 1984 1238
    • (1984) J Clin Invest , vol.74 , pp. 1238
    • Bogardus, C.1    Lillioja, S.2    Howard, B.V.3
  • 10
    • 0026817052 scopus 로고
    • Insulin, glibenclamide or metformin treatment for non–insulin-dependent diabetes: Heterogenous responses of standard measures of insulin action and insulin secretion before and after differing hypoglycaemic therapy
    • K. Boyd C. Rogers C. Boreham Insulin, glibenclamide or metformin treatment for non–insulin-dependent diabetes: Heterogenous responses of standard measures of insulin action and insulin secretion before and after differing hypoglycaemic therapy Diabetes Res 19 1992 69
    • (1992) Diabetes Res , vol.19 , pp. 69
    • Boyd, K.1    Rogers, C.2    Boreham, C.3
  • 11
    • 0024216182 scopus 로고
    • Physiological importance of deficiency in early prandial insulin secretion in noninsulin dependent diabetes
    • D.G. Bruce D.J. Chisholm L.H. Storlein Physiological importance of deficiency in early prandial insulin secretion in noninsulin dependent diabetes Diabetes 37 1988 736
    • (1988) Diabetes , vol.37 , pp. 736
    • Bruce, D.G.1    Chisholm, D.J.2    Storlein, L.H.3
  • 12
    • 33751045955 scopus 로고
    • The hypoglycaemic action of phenformin: Effect of phenformin on glucose metabolism in peripheral tissues
    • W.J.H. Butterfield M.J. Whichelow The hypoglycaemic action of phenformin: Effect of phenformin on glucose metabolism in peripheral tissues Diabetes 11 1962 281
    • (1962) Diabetes , vol.11 , pp. 281
    • Butterfield, W.J.H.1    Whichelow, M.J.2
  • 13
    • 0019212842 scopus 로고
    • Megaloblastic anaemia due to vitamin B12 malabsorption associated with long-term metformin treatment
    • 12 malabsorption associated with long-term metformin treatment BMJ 280 1988 1214
    • (1988) BMJ , vol.280 , pp. 1214
    • Callaghan, T.S.1    Tomkin, G.S.2    Hadden, D.R.3
  • 15
    • 0001172619 scopus 로고
    • Fibrinolytic effect of metformin in coronary-artery disease
    • R. Chatrvabarti E.D. Hocking G.R. Fearnley Fibrinolytic effect of metformin in coronary-artery disease Lancet 2 1965 256
    • (1965) Lancet , vol.2 , pp. 256
    • Chatrvabarti, R.1    Hocking, E.D.2    Fearnley, G.R.3
  • 16
    • 0023153344 scopus 로고
    • Resistance to insulin suppression of plasma free fatty acid concentrations and stimulation of glucose uptake in noninsulin–dependent diabetes mellitus
    • Y.D.I. Chen A. Golay A.L.M. Swislocki Resistance to insulin suppression of plasma free fatty acid concentrations and stimulation of glucose uptake in noninsulin–dependent diabetes mellitus J Clin Endocrinol Metab 64 1987 17
    • (1987) J Clin Endocrinol Metab , vol.64 , pp. 17
    • Chen, Y.D.I.1    Golay, A.2    Swislocki, A.L.M.3
  • 17
    • 0014423575 scopus 로고
    • Comparison of chlorpropamide and metformin treatment on weight and blood glucose response of uncontrolled obese diabetics
    • B.F. Clarke L.J.P. Duncan Comparison of chlorpropamide and metformin treatment on weight and blood glucose response of uncontrolled obese diabetics Lancet 1 1968 123
    • (1968) Lancet , vol.1 , pp. 123
    • Clarke, B.F.1    Duncan, L.J.P.2
  • 18
    • 0024511329 scopus 로고
    • Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM
    • A. Consoli N. Nurijhan F. Capani Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM Diabetes 38 1989 550
    • (1989) Diabetes , vol.38 , pp. 550
    • Consoli, A.1    Nurijhan, N.2    Capani, F.3
  • 19
    • 0017838931 scopus 로고
    • The effect of short-term administration of antidiabetic biguanide derivatives on the blood lactate levels in healthy subjects
    • A. Czyzyk B. Lao W. Bartosiewicz The effect of short-term administration of antidiabetic biguanide derivatives on the blood lactate levels in healthy subjects Diabetologia 14 1978 89
    • (1978) Diabetologia , vol.14 , pp. 89
    • Czyzyk, A.1    Lao, B.2    Bartosiewicz, W.3
  • 20
    • 0025837055 scopus 로고
    • Mechanism of metformin action in obese and lean non–insulin-dependent diabetic subjects
    • R.A. De Fronzo N.I.R. Barzilai D.C. Simonson Mechanism of metformin action in obese and lean non–insulin-dependent diabetic subjects J Clin Endocrinol Metab 73 1991 1294
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 1294
    • De Fronzo, R.A.1    Barzilai, N.I.R.2    Simonson, D.C.3
  • 23
    • 9244227632 scopus 로고    scopus 로고
    • Improvement of insulin sensitivity by metformin treatment does not lower blood pressure of nonobese insulin resistant hypertensive patients with normal glucose tolerance
    • M. Dorella M. Giusto V. Da Tos Improvement of insulin sensitivity by metformin treatment does not lower blood pressure of nonobese insulin resistant hypertensive patients with normal glucose tolerance J Clin Endocrinol Metab 81 1996 1568
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1568
    • Dorella, M.1    Giusto, M.2    Da Tos, V.3
  • 24
    • 85114541721 scopus 로고
    • Chemistry of the biguanides in diabetes mellitus and obesity: Phenformin hydrochloride as a research tool
    • B. Elpern Chemistry of the biguanides in diabetes mellitus and obesity: Phenformin hydrochloride as a research tool Ann NY Acad Sci 148 1988 577
    • (1988) Ann NY Acad Sci , vol.148 , pp. 577
    • Elpern, B.1
  • 25
    • 72949143647 scopus 로고
    • Metabolic effects of phenylethylbiguanide in normal subjects and in diabetic patients
    • S.S. Fajans J.A. Moorhouse H. Doorenbos Metabolic effects of phenylethylbiguanide in normal subjects and in diabetic patients Diabetes 9 1960 194
    • (1960) Diabetes , vol.9 , pp. 194
    • Fajans, S.S.1    Moorhouse, J.A.2    Doorenbos, H.3
  • 26
    • 0027368014 scopus 로고
    • Demonstration of a critical role of free fatty acids in mediating counterregulatory stimulation of gluconeogenesis and suppression of glucose utilisation in humans
    • C. Fannelli S. Calderone L. Epifano Demonstration of a critical role of free fatty acids in mediating counterregulatory stimulation of gluconeogenesis and suppression of glucose utilisation in humans J Clin Invest 92 1993 1617
    • (1993) J Clin Invest , vol.92 , pp. 1617
    • Fannelli, C.1    Calderone, S.2    Epifano, L.3
  • 27
    • 0022467221 scopus 로고
    • Mechanism of action of metformin: Insulin receptor and post-receptor effects in vitro and in vivo
    • G.I. Fantus R. Brosseau Mechanism of action of metformin: Insulin receptor and post-receptor effects in vitro and in vivo J Clin Endocrinol Metab 63 1986 898
    • (1986) J Clin Endocrinol Metab , vol.63 , pp. 898
    • Fantus, G.I.1    Brosseau, R.2
  • 28
    • 0022467301 scopus 로고
    • Postprandial hyperglycaemia in patients with noninsulin dependent diabetes mellitus: Role of hepatic and extrahepatic tissues
    • R.G. Firth P.M. Bell H.M. Marsh Postprandial hyperglycaemia in patients with noninsulin dependent diabetes mellitus: Role of hepatic and extrahepatic tissues J Clin Invest 77 1986 1525
    • (1986) J Clin Invest , vol.77 , pp. 1525
    • Firth, R.G.1    Bell, P.M.2    Marsh, H.M.3
  • 29
    • 9544247850 scopus 로고    scopus 로고
    • The effect of metformin on the metabolic abnormalities associated with upper body fat distribution
    • A. Fontbonne J.M. Cohen M.A. Charles The effect of metformin on the metabolic abnormalities associated with upper body fat distribution Diabetes Care 19 1996 920
    • (1996) Diabetes Care , vol.19 , pp. 920
    • Fontbonne, A.1    Cohen, J.M.2    Charles, M.A.3
  • 30
    • 34250928531 scopus 로고
    • Ueber synthetisch dargestellte Kiaper mit insulinartiger Wirkung auf den Normalen und diabetischen Organismus
    • E. Frank M. Nothmann A. Wagner Ueber synthetisch dargestellte Kiaper mit insulinartiger Wirkung auf den Normalen und diabetischen Organismus Klin Wochenschr 5 1926 2100
    • (1926) Klin Wochenschr , vol.5 , pp. 2100
    • Frank, E.1    Nothmann, M.2    Wagner, A.3
  • 31
    • 0028129862 scopus 로고
    • Effect of metformin on insulin-stimulated glucose transport in isolated skeletal muscle obtained from patients with NIDDM
    • D. Galuska L.A. Nolte J.R. Zierath Effect of metformin on insulin-stimulated glucose transport in isolated skeletal muscle obtained from patients with NIDDM Diabetologia 37 1994 826
    • (1994) Diabetologia , vol.37 , pp. 826
    • Galuska, D.1    Nolte, L.A.2    Zierath, J.R.3
  • 32
    • 0025726560 scopus 로고
    • Metformin causes a reduction in basal and post-venous occlusion plasminogen activator inhibitor 1 in type 2 diabetic patients
    • P.J. Grant M.H. Strickland N.A. Booth Metformin causes a reduction in basal and post-venous occlusion plasminogen activator inhibitor 1 in type 2 diabetic patients Diabet Med 8 1991 361
    • (1991) Diabet Med , vol.8 , pp. 361
    • Grant, P.J.1    Strickland, M.H.2    Booth, N.A.3
  • 33
    • 0024392514 scopus 로고
    • Glucose and free fatty acid metabolism in non–insulin-dependent diabetes mellitus: Evidence for multiple sites of insulin resistance
    • L.C. Groop R.C. Bonadonna S. Del Prato Glucose and free fatty acid metabolism in non–insulin-dependent diabetes mellitus: Evidence for multiple sites of insulin resistance J Clin Invest 84 1989 205
    • (1989) J Clin Invest , vol.84 , pp. 205
    • Groop, L.C.1    Bonadonna, R.C.2    Del Prato, S.3
  • 34
    • 0027494134 scopus 로고
    • Metformin improves glucose, lipid metabolism and reduces blood pressure in hypertensive obese women
    • D. Guigliano N. De Rosa G. Di Maro Metformin improves glucose, lipid metabolism and reduces blood pressure in hypertensive obese women Diabetes Care 16 1993 1387
    • (1993) Diabetes Care , vol.16 , pp. 1387
    • Guigliano, D.1    De Rosa, N.2    Di Maro, G.3
  • 35
    • 0027411979 scopus 로고
    • Metformin for obese, insulin treated diabetic patients: Improvement in glycaemia control and reduction of metabolic risk factors
    • D. Guigliano A. Quatraro G. Consoli Metformin for obese, insulin treated diabetic patients: Improvement in glycaemia control and reduction of metabolic risk factors Eur J Clin Pharmacol 44 1993 107
    • (1993) Eur J Clin Pharmacol , vol.44 , pp. 107
    • Guigliano, D.1    Quatraro, A.2    Consoli, G.3
  • 36
    • 33847436155 scopus 로고
    • Long-term effect of chlorpropamide therapy in maturity onset diabetes
    • D.R. Hadden D.A.D. Montgomery J.A. Weaver Long-term effect of chlorpropamide therapy in maturity onset diabetes Diabetes 11 1962 91
    • (1962) Diabetes , vol.11 , pp. 91
    • Hadden, D.R.1    Montgomery, D.A.D.2    Weaver, J.A.3
  • 37
    • 0028034406 scopus 로고
    • Antihyperglycaemic efficacy, response prediction and dose-response relations of treatment with metformin and sulphonylurea, alone and in primary combination
    • L.S. Hermann B. Schersten A. Melander Antihyperglycaemic efficacy, response prediction and dose-response relations of treatment with metformin and sulphonylurea, alone and in primary combination Diabet Med 11 1994 953
    • (1994) Diabet Med , vol.11 , pp. 953
    • Hermann, L.S.1    Schersten, B.2    Melander, A.3
  • 38
    • 0005915684 scopus 로고
    • Die Wirkung des Biguanide und seiner Derwate auf den Zuckerstoffwechsel
    • E. Hesse G. Taubmann Die Wirkung des Biguanide und seiner Derwate auf den Zuckerstoffwechsel Arch Exp Pathol Pharmak 142 1929 290
    • (1929) Arch Exp Pathol Pharmak , vol.142 , pp. 290
    • Hesse, E.1    Taubmann, G.2
  • 39
    • 0019784417 scopus 로고
    • Biguanide treatment increases the number of insulin receptor sites on human erythrocytes
    • A. Holle W. Managels M. Dreyer Biguanide treatment increases the number of insulin receptor sites on human erythrocytes N Engl J Med 305 1981 563
    • (1981) N Engl J Med , vol.305 , pp. 563
    • Holle, A.1    Managels, W.2    Dreyer, M.3
  • 40
    • 0026040202 scopus 로고
    • Effects of metformin on glucose, insulin and lipid metabolism in patients with mild hypertriglyceridaemia and non–insulin-dependent diabetes by glucose tolerance test criteria
    • C.B. Hollenbeck P. Johnston B.B. Varasteh Effects of metformin on glucose, insulin and lipid metabolism in patients with mild hypertriglyceridaemia and non–insulin-dependent diabetes by glucose tolerance test criteria Diabetes Metab 17 1991 483
    • (1991) Diabetes Metab , vol.17 , pp. 483
    • Hollenbeck, C.B.1    Johnston, P.2    Varasteh, B.B.3
  • 41
    • 0023551820 scopus 로고
    • Mechanisms of metformin action in non–insulin-dependent diabetes
    • R.A. Jackson M.I. Haura J.B. Jaspan Mechanisms of metformin action in non–insulin-dependent diabetes Diabetes 36 1987 632
    • (1987) Diabetes , vol.36 , pp. 632
    • Jackson, R.A.1    Haura, M.I.2    Jaspan, J.B.3
  • 42
    • 0026738794 scopus 로고
    • In defence of insulin: A critique of syndrome X
    • R.J. Jarrett In defence of insulin: A critique of syndrome X Lancet 340 1992 469
    • (1992) Lancet , vol.340 , pp. 469
    • Jarrett, R.J.1
  • 43
    • 0027495982 scopus 로고
    • The impact of metformin on hepatic glucose production and skeletal muscle glycogen synthase activity in overweight type II diabetic patients
    • A.B. Johnson J.M. Webster C.F. Sum The impact of metformin on hepatic glucose production and skeletal muscle glycogen synthase activity in overweight type II diabetic patients Metabolism 42 1993 1217
    • (1993) Metabolism , vol.42 , pp. 1217
    • Johnson, A.B.1    Webster, J.M.2    Sum, C.F.3
  • 44
    • 0025734531 scopus 로고
    • Increased plasma plasminogen activator inhibitor 1 levels: A possible link between insulin resistance and atherothrombosis
    • I. Juhan-Vague I. Alessi P. Vague Increased plasma plasminogen activator inhibitor 1 levels: A possible link between insulin resistance and atherothrombosis Diabetologia 34 1991 457
    • (1991) Diabetologia , vol.34 , pp. 457
    • Juhan-Vague, I.1    Alessi, I.2    Vague, P.3
  • 45
    • 0026029277 scopus 로고
    • Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors
    • K. Landin L. Tengborn V. Smith Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors J Intern Med 229 1991 181
    • (1991) J Intern Med , vol.229 , pp. 181
    • Landin, K.1    Tengborn, L.2    Smith, V.3
  • 46
    • 0023174782 scopus 로고
    • Energy expenditure in non–insulin-dependent diabetic subjects on metformin, a sulphonylurea therapy
    • P. Leslie R.T. Jung T.E. Isles Energy expenditure in non–insulin-dependent diabetic subjects on metformin, a sulphonylurea therapy Clin Sci 73 1987 41
    • (1987) Clin Sci , vol.73 , pp. 41
    • Leslie, P.1    Jung, R.T.2    Isles, T.E.3
  • 47
    • 0017843124 scopus 로고
    • Lactic acidosis in biguanide-treated diabetics: A review of 330 cases
    • D. Luft R.M. Schmulling M. Eggstein Lactic acidosis in biguanide-treated diabetics: A review of 330 cases Diabetologia 14 1978 75
    • (1978) Diabetologia , vol.14 , pp. 75
    • Luft, D.1    Schmulling, R.M.2    Eggstein, M.3
  • 48
    • 72849163588 scopus 로고
    • Effect of phenformin on peripheral glucose utilization in human diabetic and nondiabetic subjects
    • L.L. Madison R.L. Unger Effect of phenformin on peripheral glucose utilization in human diabetic and nondiabetic subjects Diabetes 9 1960 202
    • (1960) Diabetes , vol.9 , pp. 202
    • Madison, L.L.1    Unger, R.L.2
  • 49
    • 0014202058 scopus 로고
    • Specific inhibition of gluconeogenesis by biguanides
    • F. Meyer M. Ipaktchi H. Clauser Specific inhibition of gluconeogenesis by biguanides Nature 213 1967 203
    • (1967) Nature , vol.213 , pp. 203
    • Meyer, F.1    Ipaktchi, M.2    Clauser, H.3
  • 50
    • 0001856714 scopus 로고
    • Efficacy of the long-term administration of metformin in hyperlipidaemic patients
    • V. Montaguti D. Celin C. Ceredi Efficacy of the long-term administration of metformin in hyperlipidaemic patients Res Clin Forums 1 1979 95
    • (1979) Res Clin Forums , vol.1 , pp. 95
    • Montaguti, V.1    Celin, D.2    Ceredi, C.3
  • 51
    • 0027399661 scopus 로고
    • Effects of metformin on insulin resistance, risk factors for cardiovascular disease and plasminogen activator inhibitor in NIDDM subjects
    • D.K. Nagi J.S. Yudkin Effects of metformin on insulin resistance, risk factors for cardiovascular disease and plasminogen activator inhibitor in NIDDM subjects Diabetes Care 16 1993 621
    • (1993) Diabetes Care , vol.16 , pp. 621
    • Nagi, D.K.1    Yudkin, J.S.2
  • 53
    • 0017619802 scopus 로고
    • Comparative effects of phenformin, metformin and glibenclamide on metabolic rhythms in maturity onset diabetics
    • M. Natrass P.G. Todd L. Hinks Comparative effects of phenformin, metformin and glibenclamide on metabolic rhythms in maturity onset diabetics Diabetologia 13 1977 145
    • (1977) Diabetologia , vol.13 , pp. 145
    • Natrass, M.1    Todd, P.G.2    Hinks, L.3
  • 54
    • 0023136556 scopus 로고
    • Mortality and survival in type 2 (non–insulin-dependent) diabetes mellitus
    • G. Panzram Mortality and survival in type 2 (non–insulin-dependent) diabetes mellitus Diabetologia 30 1987 123
    • (1987) Diabetologia , vol.30 , pp. 123
    • Panzram, G.1
  • 55
    • 2142692516 scopus 로고
    • Phenformin in weight reduction of obese diabetics
    • D.P. Patel J.M. Stowers Phenformin in weight reduction of obese diabetics Lancet 2 1964 282
    • (1964) Lancet , vol.2 , pp. 282
    • Patel, D.P.1    Stowers, J.M.2
  • 56
    • 2442445349 scopus 로고
    • The parathyroids—tetania parathyreopriva: Parts I–VIII
    • D.N. Paton L. Findlay The parathyroids—tetania parathyreopriva: Parts I–VIII Q J Exp Physiol 10 1917 203
    • (1917) Q J Exp Physiol , vol.10 , pp. 203
    • Paton, D.N.1    Findlay, L.2
  • 57
    • 0024574110 scopus 로고
    • The effects of metformin on adipocyte insulin action and metabolic control in obese subjects with type 2 diabetes
    • O. Pedersen O. Hother-Nielsen J. Bak The effects of metformin on adipocyte insulin action and metabolic control in obese subjects with type 2 diabetes Diabet Med 6 1989 249
    • (1989) Diabet Med , vol.6 , pp. 249
    • Pedersen, O.1    Hother-Nielsen, O.2    Bak, J.3
  • 58
    • 0028342565 scopus 로고
    • Acute antihyperglycaemic mechanisms of metformin in NIDDM: Evidence for suppression of lipid oxidation and hepatic glucose production
    • G. Perriello P. Misericordia E. Volpi Acute antihyperglycaemic mechanisms of metformin in NIDDM: Evidence for suppression of lipid oxidation and hepatic glucose production Diabetes 43 1994 920
    • (1994) Diabetes , vol.43 , pp. 920
    • Perriello, G.1    Misericordia, P.2    Volpi, E.3
  • 60
    • 0021028821 scopus 로고
    • Insulin receptor binding to monocytes, insulin secretion and glucose tolerance following metformin treatment: Results of a double blind cross-over study in type II diabetics
    • R. Prager G. Schernthaner Insulin receptor binding to monocytes, insulin secretion and glucose tolerance following metformin treatment: Results of a double blind cross-over study in type II diabetics Diabetes 32 1983 1083
    • (1983) Diabetes , vol.32 , pp. 1083
    • Prager, R.1    Schernthaner, G.2
  • 61
    • 50549202600 scopus 로고
    • The glucose fatty-acid cycle: Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • P.J. Randle P.B. Garland C.N. Hales The glucose fatty-acid cycle: Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus Lancet 1 1963 785
    • (1963) Lancet , vol.1 , pp. 785
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3
  • 62
    • 84861866767 scopus 로고
    • Ueber Biguanid
    • B. Rathke Ueber Biguanid Chem Ber 12 1879 776
    • (1879) Chem Ber , vol.12 , pp. 776
    • Rathke, B.1
  • 63
    • 0024160877 scopus 로고
    • Role of insulin resistance in human disease
    • G.M. Reaven Role of insulin resistance in human disease Diabetes 37 1988 1595
    • (1988) Diabetes , vol.37 , pp. 1595
    • Reaven, G.M.1
  • 64
    • 0025907205 scopus 로고
    • Glucose and lipid metabolism in non–insulin-dependent diabetes, effect of metformin
    • A. Riccio S. Del Prato V. De Krewtzenberg Glucose and lipid metabolism in non–insulin-dependent diabetes, effect of metformin Diabetes Metab Rev 17 1991 180
    • (1991) Diabetes Metab Rev , vol.17 , pp. 180
    • Riccio, A.1    Del Prato, S.2    De Krewtzenberg, V.3
  • 65
    • 0014404009 scopus 로고
    • Circadian variation of glucose, insulin and free fatty acids during long-term use of oral hypoglycaemic agents in diabetes mellitus
    • A.N. Rigas A.H. Bittles D.R. Hadden Circadian variation of glucose, insulin and free fatty acids during long-term use of oral hypoglycaemic agents in diabetes mellitus BMJ 4 1968 25
    • (1968) BMJ , vol.4 , pp. 25
    • Rigas, A.N.1    Bittles, A.H.2    Hadden, D.R.3
  • 66
    • 0027391243 scopus 로고
    • Contribution of glucose/glucose-6-phosphate cycle activity to insulin resistance in type 2 (non–insulin-dependent) diabetes mellitus
    • D.P. Rooney R.D.G. Neely O. Beatty Contribution of glucose/glucose-6-phosphate cycle activity to insulin resistance in type 2 (non–insulin-dependent) diabetes mellitus Diabetologia 36 1993 106
    • (1993) Diabetologia , vol.36 , pp. 106
    • Rooney, D.P.1    Neely, R.D.G.2    Beatty, O.3
  • 67
    • 0028856712 scopus 로고
    • Kidney function and age are both predictors of pharmacokinetics of metformin
    • N.C. Sambol J. Chiang E.T. Lin Kidney function and age are both predictors of pharmacokinetics of metformin J Clin Pharmacol 35 1994 1094
    • (1994) J Clin Pharmacol , vol.35 , pp. 1094
    • Sambol, N.C.1    Chiang, J.2    Lin, E.T.3
  • 68
    • 0026489975 scopus 로고
    • Glucose transport in human skeletal muscle cells in culture: Stimulation by insulin and metformin
    • V. Sarabia L. Lam E. Burdett Glucose transport in human skeletal muscle cells in culture: Stimulation by insulin and metformin J Clin Invest 90 1992 1386
    • (1992) J Clin Invest , vol.90 , pp. 1386
    • Sarabia, V.1    Lam, L.2    Burdett, E.3
  • 69
    • 0018819017 scopus 로고
    • Guanidines and biguanides
    • G. Schafer Guanidines and biguanides Pharmacol Ther 8 1980 275
    • (1980) Pharmacol Ther , vol.8 , pp. 275
    • Schafer, G.1
  • 70
    • 0020953401 scopus 로고
    • Biguanides: A review of history, pharmacodynamics and therapy
    • G. Schafer Biguanides: A review of history, pharmacodynamics and therapy Diabetes Metab 9 1983 148
    • (1983) Diabetes Metab , vol.9 , pp. 148
    • Schafer, G.1
  • 71
    • 0028139101 scopus 로고
    • Reevaluation of a biguanide, metformin: Mechanism of action and tolerability
    • C.R. Sirtori C. Pasik Reevaluation of a biguanide, metformin: Mechanism of action and tolerability Pharmacol Res 30 1994 187
    • (1994) Pharmacol Res , vol.30 , pp. 187
    • Sirtori, C.R.1    Pasik, C.2
  • 72
    • 0025098765 scopus 로고
    • Quantitation of muscle glycogen synthesis in normal subjects and subjects with non–insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy
    • 13C nuclear magnetic resonance spectroscopy N Engl J Med 322 1990 223
    • (1990) N Engl J Med , vol.322 , pp. 223
    • Shulman, G.I.1    Rothman, D.L.2    Jue, T.3
  • 73
    • 0027948157 scopus 로고
    • The dyslipoproteinaemias of diabetes
    • G. Skiner The dyslipoproteinaemias of diabetes Atherosclerosis 110 suppl 1994 S27
    • (1994) Atherosclerosis , vol.110 , Issue.suppl , pp. S27
    • Skiner, G.1
  • 74
    • 0005954710 scopus 로고
    • Uber Biguanide II: Die Ulutzuckersenkende Wirkung der Biguanide
    • K.H. Slotta R. Tschesche Uber Biguanide II: Die Ulutzuckersenkende Wirkung der Biguanide Chem Ber 62 1929 1398
    • (1929) Chem Ber , vol.62 , pp. 1398
    • Slotta, K.H.1    Tschesche, R.2
  • 75
    • 0001155775 scopus 로고
    • Pharmacology and mode of action of the hypoglycaemic guanidine derivatives
    • J. Sterne Pharmacology and mode of action of the hypoglycaemic guanidine derivatives Oral Hypoglycaemic Agents: Pharmacology and Therapeutics 1969 Academic Press London 193
    • (1969) , pp. 193
    • Sterne, J.1
  • 76
    • 8944221625 scopus 로고
    • Experimental atherosclerosis and diabetes mellitus
    • R.W. Stout Experimental atherosclerosis and diabetes mellitus Diabetes and Atherosclerosis 1992 Kluwer Dordrecht 267
    • (1992) , pp. 267
    • Stout, R.W.1
  • 77
    • 0029133235 scopus 로고
    • Metabolic effects of metformin in non–insulin-dependent diabetes mellitus
    • M. Stumvoll N. Nurjhan G. Perriello Metabolic effects of metformin in non–insulin-dependent diabetes mellitus N Engl J Med 333 1995 550
    • (1995) N Engl J Med , vol.333 , pp. 550
    • Stumvoll, M.1    Nurjhan, N.2    Perriello, G.3
  • 78
    • 0028558603 scopus 로고
    • Effects of metformin treatment on whole body and splanchnic amino acid turnover in mild type 2 diabetes
    • P. Tessari G. Biolo D. Bruttomesso Effects of metformin treatment on whole body and splanchnic amino acid turnover in mild type 2 diabetes J Clin Endocrinol Metab 79 1994 1553
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 1553
    • Tessari, P.1    Biolo, G.2    Bruttomesso, D.3
  • 79
    • 0023266084 scopus 로고
    • Statement on hypertension in diabetes mellitus: Final Report
    • The Working Group on Hypertension Statement on hypertension in diabetes mellitus: Final Report Arch Intern Med 147 1987 830
    • (1987) Arch Intern Med , vol.147 , pp. 830
    • The Working Group on Hypertension1
  • 80
    • 84970809851 scopus 로고
    • Vitamin B12 status of patients on long-term metformin therapy
    • 12 status of patients on long-term metformin therapy BMJ 2 1971 685
    • (1971) BMJ , vol.2 , pp. 685
    • Tomkin, G.H.1    Hadden, D.R.2    Weaver, J.A.3
  • 81
    • 0015939083 scopus 로고
    • Malabsorption of vitamin B12 in diabetic patients treated with phenformin: A comparison with metformin
    • 12 in diabetic patients treated with phenformin: A comparison with metformin BMJ 3 1973 633
    • (1973) BMJ , vol.3 , pp. 633
    • Tomkin, G.H.1
  • 82
    • 0030034518 scopus 로고    scopus 로고
    • UK Prospective Diabetes Study 17: A 9-year update of a randomized controlled trial on the effect of improved metabolic control on complications in non–insulin-dependent diabetes mellitus
    • R. Turner C. Cull R. Holman for the UK Prospective Diabetes Study Group UK Prospective Diabetes Study 17: A 9-year update of a randomized controlled trial on the effect of improved metabolic control on complications in non–insulin-dependent diabetes mellitus Ann Intern Med 124 1996 136
    • (1996) Ann Intern Med , vol.124 , pp. 136
    • Turner, R.1    Cull, C.2    Holman, R.3    for the UK Prospective Diabetes Study Group4
  • 83
    • 0028817815 scopus 로고
    • UK Prospective Diabetes Study 16: Overview of 6 years' therapy of type II diabetes. A progressive disease
    • UK Prospective Diabetes Study Group UK Prospective Diabetes Study 16: Overview of 6 years' therapy of type II diabetes. A progressive disease Diabetes 44 1995 1249
    • (1995) Diabetes , vol.44 , pp. 1249
    • UK Prospective Diabetes Study Group1
  • 84
    • 85114548281 scopus 로고
    • Hypoglycaemic following parathyroidectomy
    • F.D. Underhill N.R. Blatherwick Hypoglycaemic following parathyroidectomy J Biol Chem 18 1914 87
    • (1914) J Biol Chem , vol.18 , pp. 87
    • Underhill, F.D.1    Blatherwick, N.R.2
  • 85
    • 0025220816 scopus 로고
    • UK Prospective Diabetes Study VI: Complications in newly diagnosed type 2 patients and their association with different clinical and biochemical risk factors
    • United Kingdom Prospective Diabetes Study Group UK Prospective Diabetes Study VI: Complications in newly diagnosed type 2 patients and their association with different clinical and biochemical risk factors Diabetes Res 13 1990 1
    • (1990) Diabetes Res , vol.13 , pp. 1
    • United Kingdom Prospective Diabetes Study Group1
  • 86
    • 0025833955 scopus 로고
    • UK Prospective Diabetes Study (UKPDS) VIII: Study design, progress and performance
    • United Kingdom Prospective Diabetes Study Group UK Prospective Diabetes Study (UKPDS) VIII: Study design, progress and performance Diabetologia 34 1991 877
    • (1991) Diabetologia , vol.34 , pp. 877
    • United Kingdom Prospective Diabetes Study Group1
  • 87
    • 84970867997 scopus 로고
    • 13: Relative efficacy of randomly allocated diet, sulphonylurea, insulin or metformin in patients with newly diagnosed non–insulin-dependent diabetes followed for three years
    • United Kingdom Prospective Diabetes Study (UKPDS) 13: Relative efficacy of randomly allocated diet, sulphonylurea, insulin or metformin in patients with newly diagnosed non–insulin-dependent diabetes followed for three years BMJ 310 1995 83
    • (1995) BMJ , vol.310 , pp. 83
    • United Kingdom Prospective Diabetes Study (UKPDS)1
  • 88
    • 0003186064 scopus 로고
    • A study of the effects of hypoglycaemic agents on vascular complications in patients with adult onset diabetes, V
    • University Group Diabetes Program A study of the effects of hypoglycaemic agents on vascular complications in patients with adult onset diabetes, V Diabetes 24 suppl 1 1975 65
    • (1975) Diabetes , vol.24 , Issue.suppl 1 , pp. 65
    • University Group Diabetes Program1
  • 89
    • 0023595143 scopus 로고
    • Metformin decreases the high plasminogen activator inhibition capacity, plasma insulin and trigyceride levels in non–diabetic obese subjects
    • P.H. Vague I. Juhan-Vague M.C. Alessi Metformin decreases the high plasminogen activator inhibition capacity, plasma insulin and trigyceride levels in non–diabetic obese subjects Thromb Haemost 57 1987 326
    • (1987) Thromb Haemost , vol.57 , pp. 326
    • Vague, P.H.1    Juhan-Vague, I.2    Alessi, M.C.3
  • 90
    • 0000149388 scopus 로고
    • Studies in the metabolic changes induced by administration of guanidine bases. 1. Influence of injected guanidine hydrochloride upon blood sugar content
    • C.K. Watanabe Studies in the metabolic changes induced by administration of guanidine bases. 1. Influence of injected guanidine hydrochloride upon blood sugar content J Biol Chem 33 1918 253
    • (1918) J Biol Chem , vol.33 , pp. 253
    • Watanabe, C.K.1
  • 91
    • 0017853392 scopus 로고
    • Blood lactate and pyruvate levels in diabetic patients treated with biguanides with and without sulphonylureas
    • A.K. Waters D.B. Morgan J.K. Wales Blood lactate and pyruvate levels in diabetic patients treated with biguanides with and without sulphonylureas Diabetologia 14 1978 95
    • (1978) Diabetologia , vol.14 , pp. 95
    • Waters, A.K.1    Morgan, D.B.2    Wales, J.K.3
  • 92
    • 0014430733 scopus 로고
    • Antimicrobial activities of biguanides
    • E.D. Weinberg Antimicrobial activities of biguanides Ann NY Acad Sci 148 1968 587
    • (1968) Ann NY Acad Sci , vol.148 , pp. 587
    • Weinberg, E.D.1
  • 93
    • 0026585914 scopus 로고
    • Metformin normalises nonoxidative glucose metabolism in insulin-resistant normoglycaemic first-degree relatives of patients with NIDDM
    • E.I.M. Widen J.G. Eriksson L.C. Groop Metformin normalises nonoxidative glucose metabolism in insulin-resistant normoglycaemic first-degree relatives of patients with NIDDM Diabetes 41 1992 354
    • (1992) Diabetes , vol.41 , pp. 354
    • Widen, E.I.M.1    Eriksson, J.G.2    Groop, L.C.3
  • 94
    • 0029134122 scopus 로고
    • Metformin-insulin interactions: From organ to cell
    • N. Wiernsperger J.R. Rapin Metformin-insulin interactions: From organ to cell Diabetes Metab Rev 11 1995 S3
    • (1995) Diabetes Metab Rev , vol.11 , pp. S3
    • Wiernsperger, N.1    Rapin, J.R.2
  • 96
    • 0023794011 scopus 로고
    • Inhibition of hepatic gluconeogenesis by metformin
    • N. Wollen C.J. Bailey Inhibition of hepatic gluconeogenesis by metformin Biochem Pharmacol 37 1988 4353
    • (1988) Biochem Pharmacol , vol.37 , pp. 4353
    • Wollen, N.1    Bailey, C.J.2
  • 97
    • 0025057564 scopus 로고
    • Effect of metformin on carbohydrate and lipoprotein metabolism in NIDDM patients
    • M.S. Wu P. Johnston W.H.H. Shen Effect of metformin on carbohydrate and lipoprotein metabolism in NIDDM patients Diabetes Care 13 1990 1
    • (1990) Diabetes Care , vol.13 , pp. 1
    • Wu, M.S.1    Johnston, P.2    Shen, W.H.H.3


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