Analysis of agonist-agonist interactions: The crucial influence of curve shape

Journal of Pharmacological and Toxicological Methods

Volumn 37, Issue 3, 1997, Pages 167-178

  Scaramellini, Clare ^a   Bennett, Gillian ^a   Leff, Paul ^a  

^a Department of Pharmacology ^*  (United Kingdom)

Author keywords

Agonist interactions; Curve shape; Dose additivity; Independence; Synergy; Theoretical analysis; Two receptor:one transducer model

Indexed keywords

PARTIAL AGONIST; RECEPTOR;

AGONIST; ARTICLE; DOSE RESPONSE; DRUG INTERACTION; DRUG POTENTIATION; DRUG RECEPTOR BINDING; MODEL; PREDICTION; SIGNAL TRANSDUCTION; TECHNIQUE; THEORETICAL STUDY;

DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; MODELS, CHEMICAL; PREDICTIVE VALUE OF TESTS; RECEPTORS, DRUG; SIGNAL TRANSDUCTION;

EID: 0030879623     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8719(97)00015-4     Document Type: Article

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