Protein kinase C as a target for cancer therapy

Antisense and Nucleic Acid Drug Development

Volumn 7, Issue 3, 1997, Pages 235-238

  Glazer, Robert I ^a  

^a GEORGETOWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; PROTEIN KINASE C;

ANTINEOPLASTIC ACTIVITY; CANCER INHIBITION; CANCER THERAPY; CONFERENCE PAPER; DRUG TARGETING; ENZYME INHIBITION; ENZYME SUBUNIT; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030879594     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1997.7.235     Document Type: Conference Paper

References (5)

1. AHMAD, S., MINETA, T., MARTUZA, R.L., and GLAZER, R.I. (1994). Antisense expression of protein kinase Cα inhibits the growth and tumorigenicity of human glioblastoma cells. Neurosurgery 35, 904-909.
2. BEHRENS, M., MARTINEZ, J.L., MORTATILLA, C., and RENART, J. (1995). Apoptosis induced by protein kinase C inhibition in a neuroblastoma cell line. Cell Growth Diff. 6, 1375-1380.
3. COLLARD, J. (1996). Signaling pathways regulated by Rho-like proteins: A possible role in tumor formation and metastasis (Review). Int. J. Oncol. 8, 3-38.
4. COULDWELL, W.T., ANTEL, J.P., and YONG, V.W. (1992). Protein kinase C activity correlates with the growth rate of malignant gliomas: Part II. Effects of glioma mitogens and modulators of protein kinase. C. Neurosurgery 31, 717-724.
5. YAZAKI, T., AHMAD, S., CHAHLAVI, A., ZYLBER.-KATZ, E., DEAN, N.M., MARTUZA, R.L., and GLAZER, R.I. (1996). Treatment of glioblastoma U-87 by systemic administration of an anti-sense protein kinase C α phosphorothioate oligodeoxynucleotide. Mol. Pharmacol. 50, 236-242.