Genetic analyses of sweet taste transduction

Food Chemistry

Volumn 60, Issue 3, 1997, Pages 311-321

  Kennedy, Linda M ^a   Eylam, Shachar ^a   Poskanzer, Jason E ^a   Saikku, Anna Riika ^a  

^a CLARK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; FRUCTOSE; GLUCOSE; MONOSACCHARIDE; SUCROSE;

ADULT; AGED; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DROSOPHILA; ELECTROPHYSIOLOGY; FEMALE; GENETIC ANALYSIS; HUMAN; HUMAN EXPERIMENT; MALE; NATURAL POPULATION; NONHUMAN; NORMAL HUMAN; SWEETNESS; TASTE; TASTE BUD;

ANIMALIA;

EID: 0030879193     PISSN: 03088146     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0308-8146(96)00337-8     Document Type: Article

References (41)

1. Avenet, P., Hofmann, F. & Lindemann, B. (1988). Transduction in taste receptor cells requires cAMP-dependent protein kinase. Nature, 333, 351-354.
2. Barnard, E. A. (1989). Molecular neurobiology - an introduction. In Molecular Neurobiology, ed. D. M. Glover & B. D. Hames Oxford University Press, Oxford, pp. 1-7.
3. Bhavsar, P. N., Rodrigues, V. & Siddiqi, O. (1983). J. Biosci., 5, 279-285.
4. Breslin, P. A. S., Kemp, S. & Beauchamp, G. K. (1994). Single sweetness signal. Nature, 369, 447-448.
5. Carson, H. L. & Stalker, H. D. (1968). Polytene chromosome relationships in Hawaiian species of Drosophila. III The D. adiastola and D. punalua subgroups. Studies in Genet., 4, 367-380.
6. Cummings, T. A., Powell, J. & Kinnamon, S. C. (1993). Sweet taste transduction in hamster taste cells: evidence for the role of cyclic nucleotides. J. Neurophysiol., 70, 2326-2336.
7. Daley, D. L. & Vande Berg, J. S. (1976). Apparent opposing effects of cyclic AMP and dibutyryl-cyclic GMP on the neuronal firing of the blowfly chemo-receptor. Biochem. Biophys. Acta, 437, 211-220.
8. Eylam, S., Kennedy, L. M. & Stevens, D. A. (1995). Potential human variants for glucose taste suggest separate fructose and glucose mechanisms. Chem. Senses, 20, 690-691 (abstract).
9. Faurion, A. (1987). Physiology of the sweet taste. Prog. Sensory Physiol., 8, 130-201.
10. Foster, K. D. & Kennedy, L. M. (1994a). IBMX and hodulcin-induced suppression of receptor cell responses to sucrose in Phormia regina. Chem. Senses, 19, 470 (abstract).
11. Foster, K. D. & Kennedy, L. M. (1994b). Sweet taste transduction mechanisms: additive effects of hodulcin and IBMX. Chem. Senses, 20, 176 (abstract).
12. Fujishiro, N., Kijima, H. & Monta, H. (1984). Impulse frequency and action potential amplitude in labellar chemosensory neurones of Drosophila melanogaster. J. Insect Physiol., 30, 317-325.
13. Gilman, A. G. (1987). G proteins: transducers of receptor-generated signals. Ann. Rev. Biochem., 56, 615-649.
14. Hagstrom, E. C. & Pfaffmann, C. (1959). The relative taste effectiveness of different sugars for the rat. J. Comp. Physiol. Psychol., 52, 259-262.
15. Hartl, D. L. (1992). Genome map of Drosophila melanogaster based on yeast artificial chromosomes. In Genome Analysis, Vol. 4: Strategies for Physical Mapping, ed. K. E. Davies & S. M. Tilghman, Cold Spring Harbor Laboratory Press, U.S., pp. 39-69.
16. Hattis, D. & Silver, K. (1994). Human interindividual variability - a major source of uncertainty in assessing risks for noncancer health effects. Risk Analysis, 14, 421-431.
17. Her, C. & Kennedy, L. M. (1991). Behavioral and neurophysiological responses to taste stimuli in Hawaiian fruitflies. Chem. Senses, 16, 533(abstract).
18. Kennedy, L. M. & Halpern, B. P. (1980). Extraction, purification and characterization of a sweetness-modifying component from Ziziphus jujuba. Chem. Senses, 5, 123-147.
19. Kennedy, L. M. (1991). Suppression of responses to sweet stimuli by the gymnemic acids, ziziphins and hodulcin. Chem. Senses, 16, 388.
20. Kennedy, L. M., Bourassa, D. M. & Rogers, M. E. (1993). The cellular and molecular neurobiology of sweet taste: Studies with taste-altering compounds. In Sweet Taste Reception, eds. M. Mathlouthi, J. A. Kanters & G. G. Birch, Elsevier Applied Science, London, pp. 317-351.
21. Kennedy, L. M. & Poskanzer, J. E. (1994). Isolation of variants for fructose or glucose taste from a natural population of Hawaiian Drosophila adiastola. In Olfaction and Taste XI, eds. K. Kurihara, N. Suzuki & H. Ogawa, Springer-Verlag, Tokyo, p. 237 (abstract).
22. Kolodny, D. E. & Kennedy, L. M. (1988). A model system for receptor cell studies with the taste modifier, hodulcin. Chem. Senses, 13, 545-557.
23. McLaughlin, S. K., McKinnon, P. J. & Margolskee, R. F. (1992). Gustducin is a taste-cell-specific G protein closely related to the transducins. Nature, 357, 563-569.
24. McLaughlin, S. K., McKinnon, P. J., Robichon, A., Spickofsky, N. & Margolskee, R. F. (1993). Gustducin and transducin: a tale of two G proteins. In The Molecular Basis of Smell and Taste Transduction (Ciba Foundation Symposium 179), Wiley, Chichester, pp. 186-200.
25. Merriam, J., Ashburner, M., Hartl, D. L. & Kafatos, F. C. (1991). Toward cloning and mapping the genome of Drosophila. Science, 254, 221-225.
26. Neer, E. J., Chow, Y. K., Garen-Fazio, S., Michel, T., Schmidt, C. J. & Silbert, S. (1990). In Biology of Cellular Transducing Signals, ed. J. Y. Vanderhoek, Plenum Press, New York, pp. 83-92.
27. Pangborn, R. M. (1963). Relative taste intensities of selected sugars and organic acids. J. Food Sci., 28, 726-733.
28. Portmann, M. O., Serghat, S. & Mathlouthi, M. (1992). Study of some factors affecting intensity/time characteristics of sweetness. Food Chem., 44, 83-92.
29. Poskanzer, J. E., Rudnick, L., Her, C. & Kennedy, L. M. (1992). Isolation of Hawaiian Drosophila variants which prefer glucose to fructose at equipotent suprathreshold concentrations. Chem. Senses, 17, 684 (abstract).
30. Poskanzer, J. E. & Kennedy, L. M. (1993). Fructose and glucose non-tasters in the Hawaiian, Drosophila adiastola. Chem. Senses, 18, 615 (abstract).
31. Rodrigues, V. & Siddiqi, O. (1981). A gustatory mutant of Drosophila defective in pyranose receptors. Mol. Gen. Genet., 181, 406-408.
32. Saikku, A.-R. (1994). Studies for cytological localization of a gene known only by it's variant phenotype: a step in the variant-to-gene-to-protein analysis of sweet taste. Biology Honors Thesis, Clark University, Worcester, MA.
33. Schiffman, S. S. & Gatlin, C. A. (1993). Sweeteners: state of knowledge review. Neurosci. Biobehav. Rev., 17, 313-345.
34. Shallenberger, R. S. & Acre, T. E. (1967). Molecular theory of sweet taste. Nature, 216, 480-482.
35. Shimada, I., Shiraishi, A., Kijima, H. & Morita, H. (1974). Separation of two receptor sites in a single labellar sugar receptor of the flesh-fly by treatment with p-chloromercuri-benzoate. J. Insect Physiol., 20, 605-621.
36. Sorsa, V. (1988). Chromosome maps of Drosophila, Vol. I and II, CRC Press, Boca Raton.
37. Striem, B. J., Pace, U., Zehavi, U., Naim, M. & Lancet, D. (1989). Sweet tastants stimulate adenylate cyclase coupled to GTP-binding protein in rat tongue membranes. Biochem. J., 260, 121-126.
38. Tanimura, T., Isono, K., Takamura, T. & Shimada, I. (1982). Genetic dimorphism in the taste sensitivity to trehalose in Drosophila melanogaster. J. Comp. Physiol., 147, 433-437.
39. Tanimura, T., Isono, K. & Yamamoto, M.-T. (1988). Taste sensitivity to trehalose and its alteration by gene dosage in Drosophila melanogaster. Genetics, 119, 399-406.
40. Tanimura, T. (1991). Genetic alteration of the multiple taste receptor sites for sugars in Drosophila. In Chemical Senses III: Genetics of Perception and Communication, eds. C. J. Wysocki & M. R. Kare, Marcel Dekker, Inc., New York, pp. 125-135.
41. Tonosaki, K. & Funakoshi, M. (1988). Cyclic nucleotides may mediate taste transduction. Nature, 331, 354-356.