Formulation of a charcoal suspension for intratumoral injection: Influence of the pluronic F68® concentration

International Journal of Pharmaceutics

Volumn 152, Issue 2, 1997, Pages 251-255

  Bonhomme Faivre, L ^a   Mathieu, M C ^b   Depraetere, P ^c   Grossiord, J L ^d   Seiller, M ^c  

^a HÔPITAL PAUL BROUSSE   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c Ecl Natl Sup Chim Clermont F   (France)

^d Lab Microbiologie Lab P   (France)

Author keywords

Charcoal; Intratumoral; Mammary tumor; Pluronic F68 ; Preoperative marking; Suspension

Indexed keywords

CHARCOAL; POLOXAMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SUSPENSION; CONTROLLED STUDY; DIFFUSION; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG STABILITY; DRUG TISSUE LEVEL; GRANULOMA; HISTOCHEMISTRY; IN VITRO STUDY; INJECTION SITE; INTRATUMORAL DRUG ADMINISTRATION; LUNG; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SUSPENSION; TUMOR;

EID: 0030878463     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(97)00074-4     Document Type: Article

References (8)

1. Bonhomme, L., Mathieu, M.C., Orbach-Arbouys, S., Seiller, M., 1996. Studies on toxicity of charcoal used in tattoing of tumors. Eur. J. Pharm. Sci. 4, 95-100.
2. Depraetere, P., 1988. Etude des dispersions industrielles par acoustophorèse. Spectra 2000 16 (132), 30-36.
3. Lane, AT., Lamkin, G.E., 1984. Paralysis of phagocyte migration due to an artificial blood substitute. Blood 64 (2), 400-405.
4. Magnusson, G., Olsson, T., Nyberg, J.A., 1986. Toxicity of pluronic F68. Toxicol. Lett. 30, 203-207.
5. Mathieu, M.C., Bonhomme, L., Travagli, J.P., Arriagada, R., Barreau-Pouhaer, L., Contesso, G., 1994. Tattoing of breast carcinoma treated by primary chemotherapy. 8th Int. Congr. Senology, Rio de Janeiro, Brasil.
6. Smith II, C.M., Hebbel, R.P., Tukey, D.P., Clawson, C.C., White, J.G., Vercellotti, G.M., 1987. Pluronic F68 reduces the endothelial adherence and improves the rheology of liganded stickle erythrocytes. Blood 69 (6), 1631-1636.
7. Vercellotti, G.M., Hammerschmidt, D.E., Craddock, P.R., Jacob, H., 1982. Activation of plasma complement by perfluorocarbon artificial blood: probable mechanism of adverse pulmonary reactions in treated patients and rationale for corticosteroid prophylaxis. Blood 59 (6), 1299-1304.
8. Virmani, R., Fink, L.M., Gunther, K., English, D., 1984. Effect of perfluorochemical substitutes on human neutrophil function. Transfusion 24 (4), 343-347.