Middle ear fluid concentrations of amoxicillin after large dosages in childhen with acute otitis media

Pediatric Infectious Disease Journal

Volumn 16, Issue 7, 1997, Pages 710-711

  Seikel, Kathleen ^a   Shelton, Sharon ^a   McCracken Jr , George H ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; BETA LACTAM ANTIBIOTIC; CLAVULANATE POTASSIUM;

ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; DOSE RESPONSE; DRUG BLOOD LEVEL; HUMAN; INFANT; MINIMUM INHIBITORY CONCENTRATION; ORAL DRUG ADMINISTRATION; OTITIS MEDIA; PENICILLIN RESISTANCE; PRIORITY JOURNAL; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE;

ACUTE DISEASE; AMOXICILLIN; CHILD; CHILD, PRESCHOOL; EAR, MIDDLE; HUMANS; OTITIS MEDIA; PENICILLINS;

EID: 0030878209     PISSN: 08913668     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006454-199707000-00014     Document Type: Article

References (7)

1. National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility tests. Sixth informational Supplement M 100-S6. Villanova, PA: National Committee for Clinical Laboratory Standards, 1995.
2. Ginsburg CM, McCracken GH, Nelson JD. Pharmacology of oral antibiotics used for treatment of otitis media and tonsillopharyngitis in infants and children. Ann Otol Rhinol Laryngol 1981;5:37-43.
3. Simon HF, Yin EF. Microbioassay of antimicrobial agents. Appl Microbiol 1978;19:573-9.
4. Thomson KS, Chartrand SA, Sanders CC, Block SL. Trovafloxacin, a new fluoroquinolone with potent activity against Streptococcus pneumoniae. Antimicrob Agents Chemother 1997;41:478-80.
5. Spangler SK, Jacobs MR, Appelbaum PC. Activities of RPR 106972 (a new oral streptogramin), cefditoren (a new oral cephalosporin), two new oxazolidinones (V-100592 and V-100766), and other oral and parenteral agents against 203 penicillin-susceptible and -resistant pneumococci. Antimicrob Agents Chemother 1996;40:481-4.
6. Craig WA, Ebert SC. Killing and regrowth of bacteria in vitro: a review. J Infect Dis 1991;74:S63-70.
7. Craig WA, Andes D. Pharmacokinetics and pharmacodynamics of antibiotics in otitis media. Pediatr Infect Dis J 1996;15:255-9.